中医药防治新冠肺炎诊疗方案的用药规律分析

Xin-yu JI; Yan MA; Shuai SHI; Si-hong LIU; Lin TONG; Cheng LYU; Hua-min ZHANG; Yan-ping WANG

doi:10.1007/s11655-021-2880-1

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中医药防治新冠肺炎诊疗方案的用药规律分析

Original Article | Updated：2022-09-08

- 中医药防治新冠肺炎诊疗方案的用药规律分析
- Medication Rule Analysis of the Diagnosis and Treatment Programs of Chinese Medicine for the Prevention and Treatment of COVID-19 in China
- Chinese Journal of Integrative Medicine 2022年28卷第9期页码：779-784
- Affiliations：
  
  1.Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing (100700), China
  2.Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing (100053), China
  3.Institute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing (100700), China
  4.Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing (100700), China
- Author bio：
  
  Prof. WANG Yan-ping, E-mail:wangyanping4816@163.com
- Funds：
  
  National Science and Technology Major Project(2018ZX10101001-005-003;2018ZX10101001-005-004);the National Key Research and Development Project(Nos.2018YFC1704401;2019YFC1709802)
- DOI：10.1007/s11655-021-2880-1
  中图分类号：
- 纸质出版日期：2022-09，
  
  网络出版日期：2022-01-13，
  
  录用日期：2020-08-28
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Xin-yu JI, Yan MA, Shuai SHI, 等. 中医药防治新冠肺炎诊疗方案的用药规律分析[J]. Chinese Journal of Integrative Medicine, 2022,28(9):779-784.

Xin-yu JI, Yan MA, Shuai SHI, et al. Medication Rule Analysis of the Diagnosis and Treatment Programs of Chinese Medicine for the Prevention and Treatment of COVID-19 in China[J]. Chinese Journal of Integrative Medicine, 2022,28(9):779-784.
Xin-yu JI, Yan MA, Shuai SHI, 等. 中医药防治新冠肺炎诊疗方案的用药规律分析[J]. Chinese Journal of Integrative Medicine, 2022,28(9):779-784. DOI： 10.1007/s11655-021-2880-1.

Xin-yu JI, Yan MA, Shuai SHI, et al. Medication Rule Analysis of the Diagnosis and Treatment Programs of Chinese Medicine for the Prevention and Treatment of COVID-19 in China[J]. Chinese Journal of Integrative Medicine, 2022,28(9):779-784. DOI： 10.1007/s11655-021-2880-1.

摘要

目的:

总结中医药防治新型冠状病毒肺炎 (以下简称“新冠肺炎”) 诊疗方案的用药规律

为临床诊治提供参考.

方法:

搜索从2019年12月8日到2020年3月10日的各省市政府网站和官方媒体网站上的中医药防治新冠肺炎诊疗方案. 分防治阶段和地区对诊疗方案的中药组方进行用药频次、中药配伍、聚类以及复杂网络分析等.

结果:

在27个中医诊治方案中

治疗处方共有203个

用药频次较高的前4位中药分别为: 甘草、杏仁、麻黄、藿香

核心组合是麻黄和杏仁. 在48个预防处方中

使用频率最高的中药分别为: 黄芪、甘草、防风、金银花等. 核心配伍处方为黄芪、甘草、防风

是玉平风散的主要成分. 中国华东地区的诊疗方案中

防治处方共45个

使用频率最多的中药是甘草、藿香、陈皮和石膏等. 中国华北地区的诊疗方案中

防治处方共50个

使用频率最多的中药是藿香、杏仁、麻黄和茯苓等.

结论:

在预防新冠肺炎方面

中医药主要侧重于提高人体免疫力; 治疗上

则重在清肺利湿. 中药处方的应用因地制宜

可能是由于气候和环境的差异

这些结果有助于临床医生快速制定中医药诊疗计划.

Abstract

Objectives:

To summarize the measures and rules of Chinese medicine (CM) and provide reference for clinical application in the prevention and treatment of coronavirus disease (COVID-19).

Methods:

The data source was from CM COVID-19 prevention and treatment programs on government websites and official media websites of the different provinces and cities. The search lasted from December 8

2019 to March 10

2020. Main variables were medication frequency and combinations of medicines. Cluster analysis and complex network analysis were used by prevention and treatment stage and by area.

Results:

Among 27 CM diagnosis and treatment plans

203 therapeutic prescriptions were enrolled

of which the top 4 herbs were:

Radix glycyrrhizae

Semen armeniacae amarum

Herba ephedrae

and

Herba agastachis

respectively. The core combinations were

Herba ephedrae

and

Semen armeniacae amarum

. Forty-eight preventive formulae were identified. Ten herbs

including

Radix Astragali seu hedysari

Radix glycyrrhizae

Radix saposhnikoviae

Flos lonicerae

etc. were most frequently used. The core prescription of CM compatibility was

Radix astragali seu hedysari

Radix glycyrrhizae

and

Radix saposhnikoviae

which is the main component of Yu Ping Feng San. There were 45 prevention and treatment prescriptions in East China; the most used CM was

Radix glycyrrhizae

Herba agastachis

Pericarpium citri reticulatae

and

Gypsum fibrosum

. Fifty prescriptions were identified in North China. According to CM analyses

Herba agastachis

Semen armeniacae amarum

Herba ephedrae

and

Poria

were most frequently used.

Conclusions:

CM for COVID-19 prevention mainly focuses on improving human immunity; for treatment

prescription focuses on clearing the lungs and removing dampness. Prescriptions vary with regions

perhaps due to climatic and environmental differences

which help clinicians to quickly make CM plans and treat patients according to clinical status

further minimizing resource wastage.

关键词

COVID-19中药用药规律

Keywords

COVID-19Chinese medicineregularity of medication

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