Low-Frequency Magnetic Stimulation of Shenmen Acupoint Reduces Blood Oxygen Levels in Prefrontal Cortex of Healthy Subjects: A Near-Infrared Brain Functional Imaging Study

Jie YUAN; Zhong ZHENG; Yue CAO; Jie CHEN; Yuan-yuan LI; Ya-ling LEI

doi:10.1007/s11655-021-3291-z

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Low-Frequency Magnetic Stimulation of Shenmen Acupoint Reduces Blood Oxygen Levels in Prefrontal Cortex of Healthy Subjects: A Near-Infrared Brain Functional Imaging Study

Acupuncture Research | Updated：2021-09-01

- Low-Frequency Magnetic Stimulation of Shenmen Acupoint Reduces Blood Oxygen Levels in Prefrontal Cortex of Healthy Subjects: A Near-Infrared Brain Functional Imaging Study
- Low-Frequency Magnetic Stimulation of Shenmen Acupoint Reduces Blood Oxygen Levels in Prefrontal Cortex of Healthy Subjects: A Near-Infrared Brain Functional Imaging Study
- Chinese Journal of Integrative Medicine 2021年27卷第8期页码：585-588
- Affiliations：
  
  1.School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu(611130), China
  2.Department of Encephalopathy, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an (710003), China
  3.Neurobiologic Testing Center, Sichuan University West China Hospital, Chengdu(610044), China
  4.College of Acupuncture and Massage, Chengdu University of Traditional Chinese Medicine, Chengdu(611130), China
  5.Department of Ophthalmology, Xi'an Hospital of Traditional Chinese Medicine, Xi'an (710003), China
- Author bio：
  
  Dr. LEI Ya-ling, E-mail: 624552101@qq.com
- Funds：
  
  the National Natural Science Foundation of China(81873354);Ministry of Science and Technology of Shaanxi Province(2018ZDXM-SF-013;2020SF-342)
- DOI：10.1007/s11655-021-3291-z
  中图分类号：
- 纸质出版日期：2021-08-01，
  
  网络出版日期：2021-04-21，
  
  录用日期：2020-05-29
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Jie YUAN, Zhong ZHENG, Yue CAO, 等. Low-Frequency Magnetic Stimulation of Shenmen Acupoint Reduces Blood Oxygen Levels in Prefrontal Cortex of Healthy Subjects: A Near-Infrared Brain Functional Imaging Study[J]. Chinese Journal of Integrative Medicine, 2021,27(8):585-588.

Jie YUAN, Zhong ZHENG, Yue CAO, et al. Low-Frequency Magnetic Stimulation of Shenmen Acupoint Reduces Blood Oxygen Levels in Prefrontal Cortex of Healthy Subjects: A Near-Infrared Brain Functional Imaging Study[J]. Chinese Journal of Integrative Medicine, 2021,27(8):585-588.
Jie YUAN, Zhong ZHENG, Yue CAO, 等. Low-Frequency Magnetic Stimulation of Shenmen Acupoint Reduces Blood Oxygen Levels in Prefrontal Cortex of Healthy Subjects: A Near-Infrared Brain Functional Imaging Study[J]. Chinese Journal of Integrative Medicine, 2021,27(8):585-588. DOI： 10.1007/s11655-021-3291-z.

Jie YUAN, Zhong ZHENG, Yue CAO, et al. Low-Frequency Magnetic Stimulation of Shenmen Acupoint Reduces Blood Oxygen Levels in Prefrontal Cortex of Healthy Subjects: A Near-Infrared Brain Functional Imaging Study[J]. Chinese Journal of Integrative Medicine, 2021,27(8):585-588. DOI： 10.1007/s11655-021-3291-z.

摘要

Abstract

Objective:

To explore the effect of low-frequency magnetic stimulation at Shenmen (HT 7) acupoint on blood oxygen levels in the prefrontal cortex of healthy subjects.

Methods:

Functional near-infrared spectroscopy (fNIRS) technology was used to collect real-time data of oxygenated hemoglobin (oxy-Hb) in the prefrontal cortex of 16 healthy subjects at resting state and low-frequency magnetic stimulation of Shenmen. The mean and integral values of blood oxygen concentration were analyzed.

Results:

Compared with the resting state

the mean and integral values of blood oxygen concentration decreased during the task period

recovery period

and the whole process in the magnetic stimulation of Shenmen acupoint (

0.05). In particular

the difference was statistically significant in the recovery period (

0.01).

Conclusions:

The prefrontal cortex was widely activated and produced an immediate effect by reducing the local blood oxygen concentration at lowfrequency magnetic stimulation of Shenmen acupoint

which verifies the sedative effect of Shenmen acupoint.

关键词

Keywords

Shenmen acupointtranscranial magnetic stimulationfunctional near-infrared spectroscopyprefrontal lobehealthy subjects

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