Ling GAO, Jin XIE, Xiao LI, 等. 透灸治疗无先兆偏头痛临床随机对照研究[J]. Chinese Journal of Integrative Medicine, 2021,27(12):927-932.
Ling GAO, Jin XIE, Xiao LI, et al. Effect and Safety of Penetrating Moxibustion in Treatment of Migraine without Aura: A Randomized Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2021,27(12):927-932.
Ling GAO, Jin XIE, Xiao LI, 等. 透灸治疗无先兆偏头痛临床随机对照研究[J]. Chinese Journal of Integrative Medicine, 2021,27(12):927-932. DOI: 10.1007/s11655-021-3327-4.
Ling GAO, Jin XIE, Xiao LI, et al. Effect and Safety of Penetrating Moxibustion in Treatment of Migraine without Aura: A Randomized Controlled Trial[J]. Chinese Journal of Integrative Medicine, 2021,27(12):927-932. DOI: 10.1007/s11655-021-3327-4.
To observe the clinical effect of penetrating moxibustion on migraine without aura (MO) patients.
Methods:
2
Totally 60 MO patients from the Acupuncture Clinic of the Third Affiliated Hospital of Henan University of Chinese Medicine were collected from November 2015 to February 2017. All patients were assigned to a treatment group and a control group using a random number table
30 cases in each group. The treatment group was treated with penetrating moxibustion
and the control group was treated with mild moxibustion
thrice a week for 4 consecutive weeks. The total effective rate
Visual Analogue Scale (VAS) scores
headache intensity
and Migraine Specific Quality of Life Questionnaire (MSQ) scores of patients after treatment were compared between the two groups. The moxibustion sensation and reaction after moxibustion were observed
and the adverse reactions were evaluated. All patients were followed up at 4 and 16 weeks after treatment.
Results:
2
The total effective rate of the treatment group was significantly higher than that of the control group (93.33% vs. 80.00%
P
<
0.05). The improvement of VAS scores
headache intensity
and the role restrictive and role preventive scores in MSQ in the treatment group was better than those in the control group (
P
<
0.05). The person-time of moxibustion sensations of itching
numbness and cold
as well as flushing and sweating after moxibustion in the treatment group were all significantly higher than that in the control group (
P
<
0.01). There was no significant difference in safety evaluation between the two groups (
P
>
0.05).
Conclusions:
2
Penetrating moxibustion can significantly relieve pain and improve quality of life of MO patients. After penetrating moxibustion
flushing and sweating of patients were obvious
and the curative effect was superior to the mild moxibustion.
关键词
Keywords
penetrating moxibustionrandomized controlled trialmigraine without auraChinese medicine
references
Bigal ME, Lipton RB. The epidemiology, burden, and comorbidities of migraine. Neurol Clin 2009;27:321-334.
Gasparini CF, Smith RA, Griffiths LR. Genetic and biochemical changes of the serotonergic system in migraine pathobiology. J Headache Pain 2017;18:20.
Chen J, Zhao L, Zheng H, Li Y, Yang MX, Chang XR, et al.Evaluating the prophylaxis and long-term effectiveness of acupuncture for migraine without aura: study protocol for a randomized controlled trial. Trials 2013;14:361.
Zhao WS, Jang ZN, Shi H, Xu LL. Low-frequency electroacupuncture alleviates chronic constrictive injury-induced mechanical allodynia by inhibiting NR2B upregulation in ipsilateral spinal dorsal horn in rats. Chin J Integr Med 2019;25:454-461.
Gao XY. Penetrating moxibustion and its clinical application.Henan Tradit Chin Med (Chin) 2007;9:33-34.
Gao XY, Chen Y, Wang X, Chen XW, Gao Y, Yang XG,et al. Study of temperature changes during abdominal transmoxibustion. Chin Acupunct Moxibust (Chin)2015;35:45-49.
Headache Classification Committee. The international classification of headache disorders. 2nd ed. Cephalalgia 2004;24:1-160.
Shi XM, ed. Acupuncture therapeutics. 6th ed. Shanghai:Shanghai Science and Technology Press;1998:91.
Zhao L, Ren YL, Liang FR. Analysis of characteristics of meridians and acupoints selected for treating migraine in past dynasties based on data excavation. Chin Acupunct Moxibust (Chin) 2009;29:467-472.
Zheng XY, ed. Guidelines for clinical research of new Chinese medicines (trial implementation). Beijing: China Medical Science and Technology Press; 2002:105.
Martin BC, Dba DSP, Sharfman MI, Adelman JU, Jhingran P. Validity and reliability of the migraine-specific quality of life questionnaire (MSQ version 2.1). Headache 2010;40:204-216.
Zhang Y, Liu YX, Sun GJ. Effect of different moxibustion treatment time on immune function of yang deficiency mice.Hubei J Tradit Chin Med (Chin) 1998;20:53-55.
Gu YH, Jin HZ, Wu YC, Li SD, Ren JN. Effect of different moxibustion dosage on serum creatine kinase after exercise.J Nanjing Univ Tradit Chin Med (Chin) 2006;22:373-375.
Yao S. Study on the correlation between moxibustion promoting toning effect and TRPV1 [Dissertation]. Nanjing:Nanjing University of Traditional Chinese Medicine; 2014.
Hou ZM. Experimental study on anti-inflammatory and immune effect of moxibustion therapy. Chin Acupunct Moxibust (Chin) 1997;4:233-235.
Jiang JF, Wang LL, Xu B, Hu L, Song XG, Wu HJ. Anti-inflammatory: effect mechanism of warming-dredging in moxibustion. Chin Acupunct Moxibust (Chin) 2013;33:860-864.
Qi L, Liu HR, Yi T, Wu LY, Liu XR, Zhao C, et al. Warming moxibustion relieves chronic visceral hyperalgesia in rats:relations to spinal dynorphin and orphanin-FQ System. Evid Based Complement Alternat Med 2013;2013:920675.
Takayama S, Seki T, Watanabe M, Takashima S, Nitta SI.Changes of blood flow volume in the superior mesenteric artery and brachial artery with abdominal thermal stimulation.Evid Based Complement Alternat Med 2009;234-235.
Feng YM. Clinical study on the treatment of migraine with moxibustion by transcranial Doppler. Pract Clin J Integr Chin West Med (Chin) 2007;10:21-22.
Takayama Y, Itoi M, Hamahashi T, Tsukamoto N, Mori K, Morishita D, et al. Moxibustion activates host defense against herpes simplex virus type Ⅰ through augmentation of cytokine production. Microbiol Immunol 2010;54:551-557.
Effect and Safety of Herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy: A Multicenter Double-Blind Randomized Controlled Trial
Reyanning Mixture on Asymptomatic or Mild SARS-CoV-2 Infection in Children and Adolescents:A Randomized Controlled Trial
Efficacy of Biejiajian Pill on Intestinal Microbiota in Patients with Hepatitis B Cirrhosis/Liver Fibrosis:A Randomized Double-Blind Controlled Trial
Efficacy of Wen-Luo-Tong on Peripheral Neuropathy Induced by Chemotherapy or Target Therapy: A Randomized,Double-Blinded, Placebo-Controlled Trial
相关作者
暂无数据
相关机构
Department of Endocrinology, Guangdong Provincial Hospital of Chinese Medicine
The Second Clinical College of Guangzhou University of Chinese Medicine
Department of Endocrinology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Guangdong Provincial Academy of Chinese Medical Sciences
Department of Endocrinology, The First Affiliated Hospital of Henan University of Chinese Medicine