Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine

ZHANG Qiao-li; LEI Ya-ling; DENG Yan; MA Rui-lin; DING Xue-song; XUE Wei; SUN Ai-jun

doi:10.1007/s11655-021-3353-2

Your Location：

Home >

Browse articles >

Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine

Review | Updated：2023-04-05

- Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine
- Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine
- 中国结合医学杂志（英文版） 2023年29卷第4期页码：361-367
- Affiliations：
  
  1.Department of Human Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing(100026), China
  2.Department of Encephalopathy, Shaanxi Provincial Hospital of Chinese Medicine, Xi'an (710000), China
  3.Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing (100730), China
- Author bio：
  
  Prof. SUN Ai-jun, E-mail: saj_pumch@sina.com
- Funds：
  
  the Fund for Beijing Science & Technology Development of Traditional Chinese Medicine(JJ-2018-73)
- DOI：10.1007/s11655-021-3353-2
  中图分类号：
- 纸质出版日期：2023-04，
  
  网络出版日期：2022-01-11，
  
  录用日期：2021-11-10
Scan for full text
Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine[J]. 中国结合医学杂志（英文版）, 2023,29(4):361-367.

ZHANG Qiao-li, LEI Ya-ling, DENG Yan, et al. Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine[J]. Chinese Journal of Integrative Medicine, 2023,29(4):361-367.
Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine[J]. 中国结合医学杂志（英文版）, 2023,29(4):361-367. DOI： 10.1007/s11655-021-3353-2.

ZHANG Qiao-li, LEI Ya-ling, DENG Yan, et al. Treatment Progress in Diminished Ovarian Reserve: Western and Chinese Medicine[J]. Chinese Journal of Integrative Medicine, 2023,29(4):361-367. DOI： 10.1007/s11655-021-3353-2.

摘要

Abstract

Diminished ovarian reserve (DOR)

generally defined as a decreased number or quality of oocytes

has a significant impact on quality of life and fertility in women. In recent years

the incidence of DOR has been increasing and the ages of patients are younger. The search for an effective DOR treatment has emerged as one of the preeminent research topics in reproductive health. An effective DOR therapy would improve ovarian function

fertility

and quality of life in patients. In this review we evaluated DOR treatment progress both in Western medicine and Chinese medicine

and elucidated the characteristics of each treatment.

关键词

Keywords

diminished ovarian reservetreatmentChinese medicineWestern medicine

references

Boucret L, Chao de la Barca JM, Morinière C, et al. Relationship between diminished ovarian reserve and mitochondrial biogenesis in cumulus cells. Hum Reprod 2015;30:1653-1664.

Greene AD, Patounakis G, Segars JH. Genetic associations with diminished ovarian reserve: a systematic review of the literature. J Assist Reprod Genet 2014;31:935-946.

Ata B, Seyhan A, Seli E. Diminished ovarian reserve versus ovarian aging: overlaps and differences. Curr Opin Obstet Gynecol 2019;31:139-147.

Chen SL. Evaluation on ovarian reserve. J Int Reprod Health Fam Plan 2009;28:281-286.

Devine K, Mumford S, Hill MJ, et al. Diminished ovarian reserve (DOR) in the US ART population: diagnostic trends among 181, 536 cycles from the society for assisted reproductive technology clinic outcomes reporting system(SART CORS). Fertil Steril 2015;104:612-619.

Cohen J, Chabbert-Buffet N, Darai E. Diminished ovarian reserve, premature ovarian failure, poor ovarian responder—a plea for universal definitions. J Assist Reprod Genet 2015;32:1709-1712.

Place TL, McGinnis LK. Klotho: spinning up some new hype for decreased ovarian reserve research? Fertil Steril 2020;114:1174.

Committee on Gynecologic Practice. Committee opinion No. 698: hormone therapy in primary ovarian insufficiency. Obstet Gynecol 2017;129:e134.

Wang Y, Han YF, Zhang CJ, et al. Clinical studies of predicting the decreasing ovarian reserve functions and improving pregnancy rate. Natl Med Front China (Chin) 2012;7:3-12.

Tamura H, Takasaki A, Taketani T, et al. The role of melatonin as an antioxidant in the follicle. J Ovarian Res 2012;5: 5.

Ozkaya MO, Naziroglu M. Multivitamin and mineral supplementation modulates oxidative stress and antioxidant vitamin levels in serum and follicular fluid of women undergoing in vitro fertilization. Fertil Steril 2010;94:2465-2466.

Xu Y, Nisenblat V, Lu C, et al. Pretreatment with CoQ10 improves ovarian response to stimulation and embryological parameters in young women with poor ovarian reserve in IVF-ICSI cycles. Reprod Biol Endocrinol 2018;16:29.

Özcan P, Fıçıcıoǧlu C, Kizilkale O, et al. Can Coenzyme Q10 supplementation protect the ovarian reserve against oxidative damage? J Assist Reprod Genet 2016;33:1223-1230.

Jiang HF, Sun XX. Progression of DHEA supplementation in women with diminished ovarian reserve. Reprod Contracep (Chin) 2014;33:306-310.

Yeung TW, Chai J, Li RH, et al. A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders. Fertil Steril 2014;102:108-115.

Li J, Yuan H, Chen Y, et al. A meta-analysis of dehydroepiandrosterone supplementation among women with diminished ovarian reserve undergoing in vitro fertilization or intracytoplasmic sperm injection. Int J Gynaecol Obstet 2015;131:240-245.

Narkwichean A, Maalouf W, Campbell B, et al. Efficacy of dehydroepiandrosterone to improve ovarian response in women with diminished ovarian reserve: a meta-analysis. Reprod Biol Endocrinol 2013;11:44.

Eftekhar M, Aflatoonian A, Mohammadian F, et al. Adjuvant growth hormone therapy in antagonist protocol in poor responders undergoing assisted reproductive technology. Arch Gynecol Obstet 2013;287:1017-1021.

Dogan S, Cicek OSY, Demir M, et al. The effect of growth hormone adjuvant therapy on assisted reproductive technologies outcomes in patients with diminished ovarian reserve or poor ovarian response. J Gynecol Obstet Hum Reprod 2021;50:101982.

Chen Y, Tao L, Lin Y, et al. Outcomes of in vitro fertilization-embryo transfer in women with diminished ovarian reserve after growth hormone pretreatment. Gynecol Endocrinol 2020;36:955-958.

Silva CA, Yamakami LY, Aikawa NE, et al. Autoimmune primary ovarian insufficiency. Autoimmun Rev 2014;13:427-430.

Panda SR, Sachan S, Hota S. A systematic review evaluating the efficacy of intra-ovarian infusion of autologous platelet-rich plasma in patients with poor ovarian reserve or ovarian insufficiency. Cureus 2020;12:e12037.

Melo P, Navarro C, Jones C, et al. The use of autologous platelet-rich plasma (PRP) versus no intervention in women with low ovarian reserve undergoing fertility treatment: a non-randomized interventional study. J Assist Reprod Genet 2020;37:855-863.

Fraison E, Crawford G, Casper G, et al. Pregnancy following diagnosis of premature ovarian insufficiency: a systematic review. Reprod Biomed Online 2019;39:467-476.

Schwarze JE, Borda P, Vásquez P, et al. Is the risk of preeclampsia higher in donor oocyte pregnancies? A systematic review and meta-analysis. JBRA Assist Reprod 2018;22:15-19.

Agarwal S, Alzahrani FA, Ahmed A. Hormone replacement therapy: would it be possible to replicate a functional ovary? Int J Mol Sci 2018;19:3160.

Perkins MS, Louw-du Toit R, Africander D. Hormone therapy and breast cancer: emerging steroid receptor mechanisms. J Mol Endocrinol 2018;61:R133-R160.

Wolberg AS, Rosendaal FR, Weitz JI, et al. Venous thrombosis. Nat Rev Dis Primers 2015;1:15006.

Chen S, He JL. Clinical experience of He Jialin in the treatment of diminished ovarian reserve. Zhejiang J Tradit Chin Med (Chin) 2014;49:22-23.

Sun AJ, Tang XD, Zhang QL, et al. Theory and clinical trial of combination of traditional Chinese medicine and Western medicine for infertile women with diminished ovarian reserve. Chin J Exp Tradit Med Form (Chin) 2019;25:1-11.

Peng YL. Clinical study on treatment of diminished ovarian reserve by nourishing Kidney and essence treatment. Guid J Tradit Chin Med Pharmacol (Chin) 2015;21:70-72.

Zhou J, Pan XY, Lin J, et al. Effects of Bushen Yiqi Huoxue Decoction in treatment of patients with diminished ovarian reserve: a randomized controlled trial. Chin J Integr Med 2022;28:195-201.

Zhang HX, Ma K, Tong YJ. Systematic review on Bushen Huoxue Recipe in treating patients suffering from diminished ovarian reserve. China J Chin Mater Med (Chin)2017;42:4464-4473.

Xu XF, Tan Y, Chen XY, et al. Effect of Bushen Huoxue Recipe on ovarian granulose cell apoptosis of DOR rats induced by GTW. J Med Res (Chin) 2009;38:123-125.

Huang C, Song K, Ma W, et al. Immunomodulatory mechanism of Bushen Huoxue Recipe alleviates cyclophosphamide-induced diminished ovarian reserve in mouse model. J Ethnopharmacol 2017;208:44-56.

Ma K, Wu JX, Zhang HX, et al. Clinical efficacy of Bushen Huoxue Culuan Formula in treatment of infertility caused by diminished ovarian reserve due to Kidney deficiency and blood stasis. China J Chin Mater Med (Chin)2021;46:2644-2649.

Liu L, Liu Y, Yang M, et al. Effectiveness of tonifying-Kidney and regulating-Liver therapy on diminished ovarian reserve: a systematic review and meta-analysis of randomized controlled trials. J Tradit Chin Med 2020;40:343-354.

Hu YL. To observe the curative effect of Chinese medicine for invigorating the Kidney to adjust menstrual cycle method combined with acupuncture on decreased ovarian reserve function of Kidney deficiency type, and to explore its effect on hormone level. J Pract Tradit Chin Med (Chin)2020;36:693-694.

Duan W, Cheng Y. Sequential therapy for Kidney-tonifying via traditional Chinese medicine effectively improves the reproductive potential and quality of life of women with decreased ovarian reserve: a randomized controlled study. Am J Transl Res 2021;13:3165-3173.

Tan ZY, You H, You ZL. Clinical observation of Dingkundan on Kidney-deficency syndrome of delayed menorrhea due to decreasing ovarian reservation. Chin J Reprod Contracep (Chin) 2018;38:406-409.

Ma K, Chen Y, Fan X, et al. Dingkun Pill replenishes diminished ovarian reserve through the PI3K/AKT/mTOR signaling pathway in TWP-induced mice. J Ethnopharmacol 2020;262:112993.

Liu Y, Gao H, Xia T, et al. An effect analysis on clinical system of infertility which caused by Kuntai Capsule on reducing the ovarian reserve. J Tianjin Univ Tradit Chin Med (Chin) 2017;36:263-266.

Gao H, Xia T, Ma R, et al. Heyan Kuntai Capsule versus dehydroepiandrosterone in treating Chinese patients with infertility caused by diminished ovarian reserve: a multicenter, randomized controlled trial. J Tradit Chin Med 2017, 37:530-537.

Maharajan K, Xia Q, Duan X, et al. Therapeutic importance of Zishen Yutai Pill on the female reproductive health: a review. J Ethnopharmacol 2021;281:114523.

Pang ZM, Liang J, Zhong XC, et al. The clinical research on Zishen Yutai Pill in the treatment of diminished ovarian reserve for 300 cases. Chin Med Modern Distance Educat China (Chin) 2017;15:43-45.

Feng Y, Chai X, Chen Y, et al. Network pharmacology approach for predicting targets of Zishen Yutai Pills on premature ovarian insufficiency. Evid Based Complement Alternat Med 2021;2021:8215454.

Liao HY, Gao J, Qiu P, et al. Qilin Pills in the treatment of 60 cases of ovarian reserv decline-induced irregular menstruation: a multicenter, single-blinded, randomize-controlled clinical trial. J Tradit Chin Med (Chin) 2019;60:2017-2112.

Li D, Jia Y, Hou Y, et al. Qilin Pill exerts therapeutic effect on resection-induced premature ovarian insufficiency rats by inhibiting the MAPK and PI3K-AKT signaling pathways. Drug Des Devel Ther 2021;15:3331-3345.

Ma R, Song J, Si J, et al. Acupuncture for diminished ovarian reserve: protocol for a systematic review and meta-analysis. Medicine (Baltimore) 2019;98:e16852.

Li X, Xu H, Fang Y, et al. Acupuncture with regulating menstruation to promote pregnancy for diminished ovarian reverse: a prospective case series study. Chin Acupunct Moxibust (Chin) 2017;37:1061-1065.

Yang FX, Yang ZX. "Thirteen acupoints for regulating menstruation and promoting pregnancy" for diminished ovarian reserve: a prospective cohort study. Chin Acupunct Moxibust (Chin) 2020;40:619-622.

Tang WL, Hu YH, He XH. Acupuncture stimulation of acupoints of multiple meridians for patients with diminished ovarian reserve of both yin and yang deficiency. Acupunct Res (Chin) 2015;40:479-483, 488.

Feng XL, Jia ZQ, Li N, et al. Effect of electroacupuncture combined with Yuyin Pill on sex hormone and Th2 cytokines in patients of decreased ovarian reserve function with Liver-Kidney yin deficiency. Chin Acupunct Moxibust(Chin) 2020;40:959-963.

Li J, Wang Y, Wu KJ, et al. Clinical research of integrated traditional Chinese Bushen Tiaogan Decoction and estrogen on infertility and repeated spontaneous abortion caused by diminished ovarian reserve. J Liaoning Univ Tradit Chin Med (Chin) 2020;22:113-116.

Huang XT, Liang SR, Wang L. Treatment of declining in ovarian reserve by shen-reinforcing and menstrual cycle-regulating therapy combined with Western medicine: a clinical observation. Chin J Integr Tradit West Med (Chin) 2014;34:688-690.

Sun Y, Tan Y, Chen S. Effectiveness of nourishing yin and tonifying yang sequential therapy in combination with Climen on diminished ovarian reserve: a retrospective study. J Tradit Chin Med 2020;40:150-156.

More>

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Research on Mechanisms of Chinese Medicines in Prevention and Treatment of Postoperative Adhesion

Effects of Bushen Yiqi Huoxue Decoction in Treatment of Patients with Diminished Ovarian Reserve:A Randomized Controlled Trial

Which Is Safer, Chinese Medicine or Western Medicine?Comparative Analysis Based on Chinese Spontaneous Reporting Database

Severe Type of COVID-19: Pathogenesis,Warning Indicators and Treatment