过量摄入栀子色素需警惕蓄积风险

Ting-ting HE; Xiao-he XIAO; Jia-bo WANG

doi:10.1007/s11655-021-3528-x

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过量摄入栀子色素需警惕蓄积风险

Case Report | Updated：2022-06-27

- 过量摄入栀子色素需警惕蓄积风险
- Excessive Intake of Gardenia Pigments Requires Vigilance against Accumulation Risk
- Chinese Journal of Integrative Medicine 2022年28卷第6期页码：545-546
- Affiliations：
  
  1.Senior Department of Hepatology, the Fifth Medical Center of Chinese PLA General Hospital, Beijing (100039), China
  2.School of Traditional Chinese Medicine, Capital Medical University, Beijing (100069), China
- Author bio：
  
  Prof. WANG Jia-bo, E-mail: jiabo_wang@ccmu.edu.cn
- Funds：
  
  National Natural Science Foundation of China(81721002;81630100;and 81573676);the National Science and Technology Major Project(2018ZX10725506-002;2018ZX10303502-002-019);Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-C-202005)
- DOI：10.1007/s11655-021-3528-x
  中图分类号：
- 纸质出版日期：2022-06-01，
  
  网络出版日期：2021-12-07，
  
  录用日期：2021-04-30
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Ting-ting HE, Xiao-he XIAO, Jia-bo WANG. 过量摄入栀子色素需警惕蓄积风险[J]. Chinese Journal of Integrative Medicine, 2022,28(6):545-546.

Ting-ting HE, Xiao-he XIAO, Jia-bo WANG. Excessive Intake of Gardenia Pigments Requires Vigilance against Accumulation Risk[J]. Chinese Journal of Integrative Medicine, 2022,28(6):545-546.
Ting-ting HE, Xiao-he XIAO, Jia-bo WANG. 过量摄入栀子色素需警惕蓄积风险[J]. Chinese Journal of Integrative Medicine, 2022,28(6):545-546. DOI： 10.1007/s11655-021-3528-x.

Ting-ting HE, Xiao-he XIAO, Jia-bo WANG. Excessive Intake of Gardenia Pigments Requires Vigilance against Accumulation Risk[J]. Chinese Journal of Integrative Medicine, 2022,28(6):545-546. DOI： 10.1007/s11655-021-3528-x.

摘要

报道1例服用含栀子中药后出现栀子蓝色素沉积现象的临床病例. 通过观察患者服用含栀子中药前后及停药后的色素沉积变化情况

收集患者一般临床资料、基础疾病情况、肝肾功能等实验室指标以及不同节点相片. 应用ImageJ软件测定眼周色素沉积的平均光密度值进行比对分析. 结果发现

患者服用含栀子中药2个月后眼周皮肤出现明显的栀子蓝色素沉积

即 "栀子蓝面容"

停药3个月后色素沉积现象逐渐消失. 虽然尚无栀子色素导致严重毒副作用的病例报道

但不建议长期服用栀子或栀子色素. 当观察到 "栀子蓝面容" 时建议停止继续用药

警惕体内栀子色素过量带来蓄积风险.

Abstract

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references

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