中医药在糖尿病视网膜病变中的优势及机制：聚焦于炎症与氧化应激

DONG Li-shuo; XUE Chong-xiang; GAO Jia-qi; HU Yue; KANG Ze-zheng; SUN A-ru; LI Jia-rui; TONG Xiao-lin; WANG Xiu-ge; LI Xiu-yang

doi:10.1007/s11655-025-3938-2

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中医药在糖尿病视网膜病变中的优势及机制：聚焦于炎症与氧化应激

Review | Updated：2025-10-23

- 中医药在糖尿病视网膜病变中的优势及机制：聚焦于炎症与氧化应激
- Advantages of Chinese Medicines for Diabetic Retinopathy and Mechanisms: Focused on Inflammation and Oxidative Stress^*
- 中国结合医学杂志（英文版） 2025年31卷第11期页码：1046-1055
- Affiliations：
  
  1.College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun (130117), China
  2.Beijing Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing (100029), China
  3.Institute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing (100053), China
  4.Department of Endocrinology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou (310009), China
  5.Department of Endocrinology, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun (130021), China
- Author bio：
  
  Dr. LI Xiu-yang, E-mail: Leexiuyang@126.com
- Funds：
  
  the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(CI2021A01602);Clinical Research Center Construction Project of Guang'anmen Hospital, China Academy of Chinese Medical Sciences(2022LYJSZX08);Postdoctoral Innovation Project in Jilin Province(14090703)
- DOI：10.1007/s11655-025-3938-2
  中图分类号：
- 录用：2025-05-30，
  
  网络出版：2025-08-15，
  
  纸质出版：2025-11
- Accepted：
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中医药在糖尿病视网膜病变中的优势及机制：聚焦于炎症与氧化应激[J]. 中国结合医学杂志（英文版）, 2025,31(11):1046-1055.

DONG Li-shuo, XUE Chong-xiang, GAO Jia-qi, et al. Advantages of Chinese Medicines for Diabetic Retinopathy and Mechanisms: Focused on Inflammation and Oxidative Stress^*[J]. Chinese journal of integrative medicine, 2025, 31(11): 1046-1055.
中医药在糖尿病视网膜病变中的优势及机制：聚焦于炎症与氧化应激[J]. 中国结合医学杂志（英文版）, 2025,31(11):1046-1055. DOI： 10.1007/s11655-025-3938-2.

DONG Li-shuo, XUE Chong-xiang, GAO Jia-qi, et al. Advantages of Chinese Medicines for Diabetic Retinopathy and Mechanisms: Focused on Inflammation and Oxidative Stress^*[J]. Chinese journal of integrative medicine, 2025, 31(11): 1046-1055. DOI： 10.1007/s11655-025-3938-2.

摘要

糖尿病性视网膜病变（DR）作为全球视力障碍的主要诱因，其患病率呈持续上升趋势。尽管现有的眼部治疗和血糖控制等治疗手段已广泛应用，仍难以有效应对这一多维度疾病。慢性炎症反应与氧化应激互为因果，触发病理级联反应，是DR发生发展的关键病理环节。中药凭借多靶点和整体调节的独特优势，其抗炎和抗氧化的双重活性已得到初步验证，然而，二者协同效应及在DR中的整合机制尚未得到系统阐明。为此，本文综述中药复方、中成药、草药及其活性成分通过抗炎和抗氧化途径干预DR的研究进展，旨在阐明其作用机制，为深入理解中药综合调控DR的分子基础及临床防治提供新思路。

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中医药在糖尿病视网膜病变中的优势及机制：聚焦于炎症与氧化应激

Advantages of Chinese Medicines for Diabetic Retinopathy and Mechanisms: Focused on Inflammation and Oxidative Stress*

DOI：10.1007/s11655-025-3938-2

摘要

Abstract

关键词

Keywords

references

Advantages of Chinese Medicines for Diabetic Retinopathy and Mechanisms: Focused on Inflammation and Oxidative Stress^*