New Paradigm for Rheumatoid Arthritis Treatment: A Review of 'Crosstalk' Mechanism of Multi-Targeted Intervention on Cytokine/Chemokine Networks by Chinese Medicine

YAN Da-wei; WAN Lei; ZHANG Xiao-jun; Fang Hao-xiang; WANG Si-yu; ZHANG Meng-yu; LI Feng

doi:10.1007/s11655-025-4232-z

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New Paradigm for Rheumatoid Arthritis Treatment: A Review of 'Crosstalk' Mechanism of Multi-Targeted Intervention on Cytokine/Chemokine Networks by Chinese Medicine

Review | Updated：2026-08-04

- New Paradigm for Rheumatoid Arthritis Treatment: A Review of 'Crosstalk' Mechanism of Multi-Targeted Intervention on Cytokine/Chemokine Networks by Chinese Medicine
- New Paradigm for Rheumatoid Arthritis Treatment: A Review of 'Crosstalk' Mechanism of Multi-Targeted Intervention on Cytokine/Chemokine Networks by Chinese Medicine
- 中国结合医学杂志（英文版） 2026年32卷第5期页码：459-469
- Affiliations：
  
  1.Department of Rheumalogy, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei ( 230031), China
  2.The First Clinical Medical College, Anhui University of Chinese Medicine, Hefei ( 230038), China
  3.Xin'an Institute of Medicine and Modernization of Traditional Chinese Medicine, Hefei ( 230012), China
  4.Key Laboratory of Xin'an Medical Education Ministry, Hefei ( 230012), China
- Author bio：
  
  Prof. WAN Lei, E-mail: yxwanlei@163.com
- Funds：
  
  National Natural Science Foundation of China(82274501;82474482);Anhui Provincial Natural Science Foundation(2308085MH291);2023 Annual Natural Science Research Project of Anhui Provincial Universities(2023AH050814)
- DOI：10.1007/s11655-025-4232-z
  中图分类号：
- 录用：2025-10-03，
  
  网络首发：2026-01-16，
  
  纸质出版：2026-05
- Accepted：
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YAN Da-wei, WAN Lei, ZHANG Xiao-jun, 等. New Paradigm for Rheumatoid Arthritis Treatment: A Review of 'Crosstalk' Mechanism of Multi-Targeted Intervention on Cytokine/Chemokine Networks by Chinese Medicine[J]. 中国结合医学杂志（英文版）, 2026,32(5):459-469.

YAN Da-wei, WAN Lei, ZHANG Xiao-jun, et al. New Paradigm for Rheumatoid Arthritis Treatment: A Review of 'Crosstalk' Mechanism of Multi-Targeted Intervention on Cytokine/Chemokine Networks by Chinese Medicine[J]. Chinese Journal of Integrative Medicine, 2026, 32(5): 459-469.
YAN Da-wei, WAN Lei, ZHANG Xiao-jun, 等. New Paradigm for Rheumatoid Arthritis Treatment: A Review of 'Crosstalk' Mechanism of Multi-Targeted Intervention on Cytokine/Chemokine Networks by Chinese Medicine[J]. 中国结合医学杂志（英文版）, 2026,32(5):459-469. DOI： 10.1007/s11655-025-4232-z.

YAN Da-wei, WAN Lei, ZHANG Xiao-jun, et al. New Paradigm for Rheumatoid Arthritis Treatment: A Review of 'Crosstalk' Mechanism of Multi-Targeted Intervention on Cytokine/Chemokine Networks by Chinese Medicine[J]. Chinese Journal of Integrative Medicine, 2026, 32(5): 459-469. DOI： 10.1007/s11655-025-4232-z.

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