Latest Issue
2011 Year 17 Vol. 1 Issue
EditorialNotes
- Keywords：Traditional Chinese Medicine;Western Medicine;Residency Training;Academic Medicine;Conventional Medicine
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- 11
Published：2021-08-27 - Abstract：The basic concept of integrative medicine (IM) is that by combining mainstream (biomedicine) with complementary and alternative medicine (CAM), synergistic therapeutic effects can be attained. When the methods of mind/body medicine (MBM) are added to this combination, as in Western countries, a new concept emerges that drastically changes the approach toward illness. It is interesting to note that the joining of traditional Chinese medicine and Western medicine in the early days of the Peoples’ Republic of China preceded the Western model of IM by almost 50 years. Several elements that make up the key components of IM as practiced today in the West were already present in the Chinese version of IM, and Chinese medicine has played and continues to play an important role in advancing IM. However, one of the major differences between the Chinese and the Western models of IM today, besides MBM and some other treatment options, is that Western integrative medicine (WIM) strictly requires its CAM methods to be supported by scientific evidence. The therapeutic methods of IM and their applications are many and varied. However, they are most frequently employed to treat chronic medical conditions, e.g., bronchial asthma, rheumatic disease, chronic inflammatory bowel disorder and chronic pain. Other fields in which IM may be applied are internal medicine (inflammatory bowel diseases and cardiovascular diseases), musculoskeletal disorders, oncology (chemotherapy-induced side effects), obstetrics and gynecology (dysmenorrhea, endometriosis, infertility and menopausal complaints), pediatrics, geriatrics, neurology (migraine and chronic headache), and psychiatry (anxiety and depression). The concept of WIM is discussed here in detail by reviewing its scope and implications for the practice of medicine and focusing on the role of Chinese medicine in WIM.Keywords：Integrative Medicine;complementary and alternative medicine;Traditional Chinese Medicine;integrative oncology;evidence-based medicine;Chinese Herbal Medicine;acupuncture
- 2602
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- 63
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- 59
Published：2021-08-27 - Abstract：The paper explores the concept of integrative medicine (IM) in relation to complementary and alternative medicine (CAM). It contrasts IM available in China to its availability in the West. The second part of the paper highlights tools which could facilitate opportunities for IM. The paper concludes with a plea to ensure and maintain the integrity of traditional Chinese medical practice, and to continue to increase developing the evidence base through a funded European Coordination Action between EU member states and China.Keywords：Integrative Medicine;Traditional Chinese Medicine;evidence based medicine
- 1928
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- 55
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- 32
Published：2021-08-27 - Abstract：To observe the effect of Aike Mixture (艾可合剂, AKM) on prostatic inflammatory: infiltration in patients with chronic prostatitis type III A (III A-CP/CPPS) and evaluate its anti-inflammatory action. A total of 60 patients with III A-CP/CPPS suitable to operation and differentiated as Chinese medicine: Gan (肝)-qi stagnancy syndrome type were selected. They were assigned with the random number table to two groups equally. Before operation, the patients in the treated group were administered with Proscar combined with AKM, but those in the control group treated with Proscar only. Suprapubic transvesical prostatectomy was performed two weeks later, and prostatic pathological examination was conducted. Grading of: inflammatory cell infiltration showed that the mean grade in the treated group was 0.78±0.90 grades, which was sihnificantly lower than that in the control group 1.68±0.87 grades (P<0.05). However, the two groups were not different in the grades of fibroblast proliferation (1.50±0.70 grades vs 1.62±0.87 grades, P>0.05). AKM could suppress the inflammatory cell infiltration, be an effective and safe remedy for the treatment of IIIA-CP/CPPS of Gan-qi stagnancy syndrome type, and worthy for spreading in clinical use.Keywords：Aike Mixture;Chinese Medicine;Chronic Prostatitis;pathology;inflammatory infiltration
- 1410
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- 55
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- 6
Published：2021-08-27 - Abstract：To explore the effect of Chinese drugs for supporting essence and strengthening Pi (脾, SESP) combining with chemotherapy on the quality of life (QOL) in the children with solid tumor. Using a digital table, 146 children with solid tumor were randomized into two groups, 77 in the control group and 69 in the treated group. They received conventional chemotherapy, but to the patients in the treated group, SESP were administered additionally. The patients’ scores of QOL and adverse reaction occurred were compared. The states in the treated group were superior to those in the control group. Statistical analysis showed that in the fifirst year, the two groups were different in terms of somatic function, systemic symptoms, and general status (P<0.05) and also in the occurrence of adverse reaction (P<0.01). In the second year, the difference was shown in aspects of somatic function and adverse reaction occurrence (P<0.05). Chinese drugs for SESP combining with chemotherapy could raise tumor patients’ QOL by improving their somatic function and clinical symptoms.Keywords：children solid tumor;Chinese Drug;quality of life
- 1670
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- 57
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- 2
Published：2021-08-27 - Abstract：To investigate the effects of Xiezhuo Chubi Decoction (泄浊除痹方, XZCBD) on the microRNA expression patterns of kidney in mice with hyperuricemia. Sixty Kunming male mice were randomly divided into the high-, medium-, and low-dose XZCBD groups, benzbromarone group, model group, and control group. Except the control group, all mice were established with yeast method combined with uricase inhibition method to build hyperuricemia model, and the corresponding drugs (37.5 g/kg, 18.75 g/kg, 9.375 g/kg, and 0.02 g/kg per day) were administrated on the 7th day. On the 22nd day, the blood uric acid concentration was detected, and microRNA with obvious changes in kidney was screened with qRT-PCR. The uric acid in the model group was higher than that in the control group, and the levels of the uric acid were reduced after being treated with XZCBD; the differences among groups were signifificant (P<0.05). Compared with the control group, 32 kinds of microRNA expression changes were detected on the 15th day after being treated with high-dose XZCBD by microRNA expression profifile screening. Among them, miR-34a could inhibit the expression of human urate anion exthanger 1, and miR-146a might have inhibited the inflflammatory reaction. XZCBD could significantly reduce the serum uric acid level; its effect on hyperuricemia might be through affecting microRNA expressions.Keywords：hyperuricemia;kidney;microRNAs;human urate anion exthanger 1
- 1660
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- 63
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- 11
Published：2021-08-27 - Abstract：To explore the effect of Bushen Huoxue Decoction (补肾活血饮, BHD) on the orphan receptor (Nurr1) and tyrosine hydroxylase (TH) in the brain of rats with Parkinson’s disease (PD). One hundred and twenty SD rats were divided into 100 in the model group and 20 in the normal control group, fififtyeight SD rats from the model group, established into PD model successfully by injuring their substantia nigra (SSN) with 6-hydroxydopamine, were divided equally into the model group and the test group, and they were treated with saline and BHD, respectively, for eight successive weeks. The change in the rats’ behavior before and after treatment was observed by counting the cycles of rotation induced by apomorphine injection; the pathology of neurons, level of Nurr1 mRNA expression, and amount of TH positive cells in SSN were observed after treatment. The rats’ behavior was improved in the tested group signifificantly, the rotation cycle after treatment being 84.0±20.0 cycles/40 min, which was signifificantly lower than that in the model group (377.0 ±62.3 cycles/40 min, P<0.01). Besides, the Nurr1 mRNA expression and TH positive cell in the test group were 0.97±0.15 and 49.40±14.72, respectively, which were signifificantly higher than those in the model group, 0.22±0.03 and 5.45±2.58, respectively (all P<0.01). BHD could treat PD by enhancing the Nurr1 mRNA expression, increasing the TH content in brain, and promoting the repairing of injured neuron in cerebral SSN.Keywords：Parkinson’s disease;Bushen Huoxue Decoction;Chinese Medicine;Orphan receptor;Tyrosine Hydroxylase
- 1422
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- 57
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- 7
Published：2021-08-27 - Abstract：To summarize and critically evaluate the evidence for and against the effectiveness of Eastern-Western integrative medicine (EWIM) for health care compared to Eastern medicine (EM) or Western medicine (WM) alone. Systematic searches were conducted on fifi ve Korean medical databases. Manual searches were also conducted through nine major Korean medical journals. Prospective randomized clinical trials (RCTs) were included if EWIM was tested for any type of conditions compared to EM or WM. There were one hundred forty-one possibly relevant studies were identififi ed, and seven RCTs were included. The risk of bias was high in most studies. The EWIM methods were compared with EM or WM in patients with pain conditions in four studies. These studies showed favorable effects of EWIM on pain reduction in patients with shoulder pain and chronic headache compared with EM, while the other RCTs failed to do so in traffic injury patients. Two studies tested EWIM in patients with Bell’s palsy compared with EM and found acute functional improvement. An RCT comparing EWIM with WM in patients with acne showed a signififi cant difference. The results of our systematic review suggest that there is limited evidence for the superiority of EWIM over EM or WM in the treatment of pain and acute symptom improvement in patients with Bell’s palsy. The evidence from our analysis was limited from the low number of RCTs included and the high risk of bias. Future RCTs appear to be warranted.Keywords：Eastern-Western integrative medicine;systematic review;randomized clinical trial;Korean literature
- 1523
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- 52
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- 7
Published：2021-08-27 - Keywords：Bone Mineral Density;Osteoporosis;postmenopausal osteoporosis;Primary Osteoporosis;Promote Blood Circulation
- 1796
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- 62
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- 19
Published：2021-08-27 - Abstract：To study the relationship between 500 kinds of commonly used Chinese herbal medicine and the classification of their efficacies in Chinese Materia Medica in relation to the common diseases listed in Internal Medicine. Database retrieval frequency of the quantitative statistical method was adopted. First, the 8 980 kinds of Chinese herbal medicine recorded in Chinese Materia Medica were used as the original search objects, and 4 493 kinds which were cited in more than five articles were picked out and then rechecked for further title citations. Second, as judged based on the Criterion, the numbers of articles which included the medicines in the line of standards were examined. As a result, 500 species of Chinese herbal medicine were singled out based on their retrieval frequency and were then used for compilation of the classification statistics according to their efficacy and the common diseases in Internal Medicine. From the classification of Chinese medicines, herbs with wide efficiency and a meek nature had higher frequencies, but those which were not appropriate as decoctions had relatively lower frequencies. However, according to the average frequency, the Chinese herbal medicine for nourishing qi and tonifying blood, at 36 346 times and 34 544 times, respectively, were the most commonly used. Analyzed from the frequency of application of the Chinese medicine in the treatment of common diseases, most of the top 10 kinds of Chinese herbal medicine with the highest frequencies generally coincided with the 500 selected medicines. In addition, the Chinese medicines with clear pharmacological efficiency were easily isolated and purified to be made into injections, although other forms are more commonly used. The results of the research objectively reflected the current applications of Chinese herbal medicine, and could be used as references in teaching, research, clinical applications, and in compiling and increasing the drugs in textbooks and Pharmacopoeia.Keywords：Chinese Herbal Medicine;Chinese Materia Medica;application;information research
- 1482
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- 50
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- 10
Published：2021-08-27
OriginalPaper
- Abstract：Colorectal cancer (CRC) remains one of the major causes of cancer death worldwide. In recent years, the development of new and effective management options, such as fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET), total mesorectal excision (TME) and monoclonal antibody novel “targeted” therapies has led to a considerable improvement in the outcome of this disease. In China, studies on CRC using integrative medicine (IM) have made remarkable progress. We therefore review the recent developments in CRC treatment through IM and Western medicine, including research studies such as the exploitation of Chinese herbs for the disruption of the tumor cell cycle or inhibition of tumor cell proliferation, induction of tumor cell apoptosis, improvement of the immune system, and the curative effect of chemotherapy. We also examine clinical studies such as those on special prescriptions and medicines and IM in anti-cancer therapy. Particularly, we analyze the advantages and disadvantages of management with IM, and propose a suggestion for the management of colorectal cancer with IM, such as screening for effective prescriptions. We also analyze Chinese medicine, studying the pharmacologic mechanism of its anti-cancer effect, further strengthening the study of IM on CRC.Keywords：colorectal cancer;Integrative Medicine;Chinese herbs;pharmacologic mechanism
- 1597
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- 50
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- 6
Published：2021-08-27
ReviewPaper
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