Supported by 2019 Hannam University Research Fund,Conflict of Interest,The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.,Authors Contributions,Park YS, Nam GH, Jo KJ, and Kawk HW carried out HPLC, MTT assay, determination of apoptosis by annexin V dead cell staining, cell cycle arrest assay, Western blotting, xenograft model, immunohistochemistry and TUNEL assay. Park YS wrote the paper. All authors read, designed and approved the final manuscript.