Supported by the National Natural Science Foundation of China (No. 81960751, 81660705) and Guangxi Young and Middle-aged Teachers’ Research Ability Improvement Project (No. 2020KY59009), Guangxi Zhuangyao Pharmaceutical Key Laboratory (No. GXZYZZ2019-1, GXZYZZ2020-07), Guangxi Natural Science Foundation Youth Project (No. 2020GXNSFBA297094), Guangxi University of Traditional Chinese Medicine School-level Project Youth Fund (No. 2020QN006),Conflict of Interest,The authors declare that there are no financial conflicts of interest.,Author Contributions,Zheng Y and Zhao TJ designed this experiment. Zheng Y and Wang L performed the molecular biology detection and wrote this article; Liu LL and Wang JH were responsible for the pathology detection; Zheng Y and Zhao TJ revised this article. And all authors agreed the final version for publication.