Supported by the National Key Research and Development Program of the Ministry of Science and Technology (No. 2018YFC1705204), the Major Science and Technology Project of Anhui Province (No. 17030801009), the Key Research and Development Projects of Foreign Scientific and Technological Cooperation planned in Anhui Province (No. 201904b11020011), the Anhui Provincial Laboratory of Internal Medicine Application and Development of Modern Chinese Medicine (No. 2016080503B041), the Construction Project of LIU Jian Studio of Traditional Chinese Medicine in Anhui Province (Secretary of Development of Traditional Chinese Medicine [2018] No. 11), and the 12th Batch of the “115” Innovation Team in Anhui Province (No. 1 [2019] of the Anhui Talent Office),Conflict of Interest,The authors declare that there are no conflicts of interest associated with this work.,Author Contributions,Liu J conceived of and designed the study; Huang D wrote the manuscript; Xin L provided technical support for the data mining; Huang D and Xin L extracted and analysed the data; Xie JG provided guidance on the analysis and writing; and Zhu Q, Chen PS, Shen ZB, Meng QH, and Wang HY identified subjects and the collected clinical data.