Supported by a grant of National Research Foundation of Korea (No. 2018R1D1A1A09083797),Conflict of Interest,Authors declare no conflict of interest.,Author contributions,Rhee MH and Jeon BR designed and conceptualized the study. Jeon BR and Irfan M performed experiments, and wrote the manuscript. Irfan M critically revised the manuscript. Lee SE, Lee JH, and Rhee MH technically assisted in the experiments and preparation of the manuscript. Rhee MH supervised the whole research work. All authors read and approved the final manuscript.