Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization

Yong-qiang Li; Mei Jin; Sheng-lei Qiu; Pei-li Wang; Tian-gang Zhu; Cheng-long Wang; Tian-chang Li; Hong-xu Liu; Hong Bian; Li-fang Yao; Da-zhuo Shi

doi:10.1007/s11655-009-0019-7

Your Location：

Home >

Browse articles >

Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization

Updated：2021-08-27

- Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization
- Chinese Journal of Integrative Medicine Vol. 15, Issue 1, Pages: 19-25(2009)
- Affiliations：
  
  1. Cardiovascular Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Department of Internal Cardiac Medicine, Beijing Hospital of Traditional Chinese Medicine Affiliated to the Capital Medical University,Beijing,China
  3. Department of Internal Cardiac Medicine, the People’s Hospital of Peking University,Beijing,China
  4. Department of Internal Cardiac Medicine, Tongren Hospital Affiliated to the Capital Medical University,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Key Technologies Research and Development Program of China during the 10th Five-Year Plan Period (No. 2003BA712A11)
- DOI：10.1007/s11655-009-0019-7
  CLC：
- Published：2009，
  
  Published Online：7 March 2009，
Scan for full text
Li, Yq., Jin, M., Qiu, Sl. et al. Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization., Chin. J. Integr. Med. 15, 19–25 (2009). https://doi.org/10.1007/s11655-009-0019-7

Yong-qiang Li, Mei Jin, Sheng-lei Qiu, et al. Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization. [J]. Chinese Journal of Integrative Medicine 15(1):19-25(2009)
Li, Yq., Jin, M., Qiu, Sl. et al. Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization., Chin. J. Integr. Med. 15, 19–25 (2009). https://doi.org/10.1007/s11655-009-0019-7 DOI：

Yong-qiang Li, Mei Jin, Sheng-lei Qiu, et al. Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization. [J]. Chinese Journal of Integrative Medicine 15(1):19-25(2009) DOI： 10.1007/s11655-009-0019-7.

摘要

To observe the effects of Chinese drugs for supplementing qi

nourishing yin and activating blood circulation on the myocardial perfusion in acute myocardial infarction (AMI) patients after revascularization. Eighty patients with anterior or inferior ventricular wall AMI

who had received revascularization by intravenous thrombolysis or coronary bypass

were randomized into the treated group and the control group equally

both treated with conventional Western medical treatment

but combined

respectively

with Xinyue Capsule (心悦胶囊

XYC) plus Composite Salvia Tablet (CST) and placebo for 3 months. Dobutamine stress echocardiography (DSE) was performed 14 days and 3 months after revascularization

respectively on every patient to observe blood perfusion extent (b value)

myocardial perfusion velocity (k value) and local blood fl ow volume (k × b) in left ventricular infarction-related vascular segments under stressed state. With 5 cases dropping out in the observation period (3 in the treated group and 2 in the control group)

the trial was completed in 75 patients in total. The 14-day DSE shows that the b value and k × b value of left anterior ventricular wall mid segment and apex segment

and the k value of apex segment in patients with anterior wall AMI

as well as the b value and k × b of basal segment in patients with inferior wall AMI in the treated group were significantly higher than those in the control group (P<0.05 or P<0.01). The 3-month DSE shows that the b value of apex segment

k × b value of basal segment

mid segment and apex segment of left anterior ventricular wall in patients with anterior wall AMI as well as the b value and k × b value of basal segment of left inferior ventricular wall in patients with inferior wall AMI were all higher in the treated group than those in the control group

respectively (P<0.05). The comparison between 14-day DSE and 3-month DSE in the treated group showed that the b value of apex segment of left anterior ventricular wall in patients with anterior wall AMI and the k × b value of apex segment and mid segment of left inferior ventricular wall in patients with inferior wall AMI significantly increased along with the on-going treatment (P<0.05). Therapy with Chinese drugs for supplementing qi

nourishing yin and activating blood circulation in combination with conventional Western medical treatment could obviously improve the blood perfusion at the myocardial tissue level in infarction-related vascular segments.

Abstract

To observe the effects of Chinese drugs for supplementing qi

who had received revascularization by intravenous thrombolysis or coronary bypass

were randomized into the treated group and the control group equally

both treated with conventional Western medical treatment

but combined

respectively

with Xinyue Capsule (心悦胶囊

XYC) plus Composite Salvia Tablet (CST) and placebo for 3 months. Dobutamine stress echocardiography (DSE) was performed 14 days and 3 months after revascularization

respectively on every patient to observe blood perfusion extent (b value)

the trial was completed in 75 patients in total. The 14-day DSE shows that the b value and k × b value of left anterior ventricular wall mid segment and apex segment

and the k value of apex segment in patients with anterior wall AMI

k × b value of basal segment

关键词

Chinese drugs for supplementing qinourishing yin and activating blood circulationacute myocardial infarctionblood circulation rebuildingmyocardial perfusionDoppler’s ultrasonic acoustic photography

Keywords

Chinese drugs for supplementing qinourishing yin and activating blood circulationacute myocardial infarctionblood circulation rebuildingmyocardial perfusionDoppler’s ultrasonic acoustic photography

references

Tanaka A, Kawarabayashi T, Nishibori Y, Sano T, Nishida Y, Fukuda D, et al. No-reflow phenomenon and lesion morphology in patients with acute myocardial infarction. Circulation 2002;105:2148–2152.

Lee KW, Norell MS. Management of ‘no-refl ow’ complicating reperfusion therapy. Acute Card Care 2008;10:5–14.

Chinese Society of Cardiovascular Diseases, Chinese Medical Association and the Editorial Committee of Chinese Journal of Cardiology. Guidance on diagnosis and treatment of acute myocardial infarction. Chin J Cardiol (Chin) 2001;29: 705–720.

Cooperation Group of Xiongbi and emergency. Norm for emergent diagnosis and treatment of Xiongbi and Xinjue (coronary artery disease and myocardial infarction). J Emerg Tradit Chin Med (Chin) 1995;4:183–185.

Editorial Committee of Chinese Journal of Cardiology. Reference proposal of thrombolytic therapy on acute myocardial infarction. Chin J Cardiol (Chin) 1996;24:328–329.

Zhou YC, Guo WL, eds. Ultrasonic medicine. 5th ed. Beijing: Scientific and Technical Documents Publishing House; 2006:401–402.

Brosh D, Assali AR, Mager A, Porter A, Hasdai D, Teplitsky I, et al. Effect of no-reflow during primary percutaneous coronary intervention for acute myocardial infarction on sixmonth mortality. Am J Cardiol 2007;99:442–445.

Stone GW, Webb J, Cox DA, Brodie BR, Qureshi M, Kalynych A, et al. Distal microcirculatory protection during percutaneous coronary intervention in acute ST-segment elevation myocardial infarction: a randomized controlled trial. JAMA 2005;293:1063–1072.

Chen KJ, Shi DZ. Thinking and methods of traditional Chinese medicine for treatment and prevention of restenosis after coronary artery stenting. Chin J Inform Tradit Chin Med (Chin) 1996;5:35.

Zhang MZ, Wang L. Deng tie-tao’s TCM syndrome differentiation for patients of coronary heart disease after coronary artery bypass graft. J Tradit Chin Med (Chin) 2006;5:32–33.

Xiyuan Hospital, China Academy of Chinese Medicine. Efficacy analysis of Kangxingeng Mixture on the treatment of 118 patients with acute Myocardial infarction. Chin J Intern Med (Chin) 1976;4:212–215.

Wang CL, Shi DZ, Yin HJ, Chen KJ. Effect of Panax quinquefolius saponin on angiogenesis and expressions of VEGF and bFGF in myocardium of rats with acute myocardial infarction. Chin J Integr Tradit West Med (Chin) 2007;27:331–334.

Ji HG, Si L, Si XC, Zhang Q. Progress on protection of salvia miltiorrhiza on cardiac ischemia-reperfusion injuries. Guangming Tradit Chin Med (Chin) 2006;21:52–53.

Wang H, Huang L, Jin J, Song YM, Gen ZH, Yu XJ, et al. Comparing evaluative methods on myocardial reperfusion after percutaneous coronary intervention. Chin J Intervent Cardiol (Chin) 2006;14:327–330.

Guo SZ, Shu XH, Pan CZ, Li YL, Ge JB, Chen HZ. Relationship between myocardial perfusion and contractile function by use of dobutamine stressing realtime myocardial contrast echocardiography. Chin J Ultrasonography (Chin) 2005;14:485–489.

Baskot B, Obradovic S, Ristic-Angelkov A, Orozovic V, Ristic-Angelkov A, Romanovic R, et al. Myocardial damage size assessment in the zone of infarction for indicating rescue percutaneous coronary intervention. Vojnosanit Pregl 2008;65:61–63.

FULL TEXT LINK

More>

Views

341

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Protective effect of Chinese herbs for supplementing qi, nourishing yin and activating blood circulation on heart function of patients with acute coronary syndrome after percutaneous coronary intervention

Clinical efficacy of traditional chinese medicine on acute myocardial infarction—A prospective cohort study

Effects of Tongguan Capsule (通冠胶囊) on post-myocardial infarction ventricular remodeling and cardiac function in rats

Combined therapy with Chinese medicine and percutaneous transradial coronary intervention for a centenarian patient with acute myocardial infarction

Shi Da-zhuo (史大卓) —An outstanding cardiologist of integrative medicine

Related Author

No data

Related Institution

Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University

Xiyuan Hospital, China Academy of Chinese Medical Sciences

Cardiovascular Diseases Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences

Division of Emergency, the Second Clinical College of Guangzhou University of Traditional Chinese Medicine

Heart Center, Guangdong Provincial Hospital of Chinese Medicine

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰