Serum low-density lipoprotein and heart rate related to the effectiveness in the treatment of angina pectoris with two similar Chinese medicine herbal formulae

Shi-yan Yan; Chen Yao; Xiao-rong Ding; Miao Jiang; Ai-ping Lu

doi:10.1007/s11655-011-0933-6

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Serum low-density lipoprotein and heart rate related to the effectiveness in the treatment of angina pectoris with two similar Chinese medicine herbal formulae

Updated：2021-08-27

- Serum low-density lipoprotein and heart rate related to the effectiveness in the treatment of angina pectoris with two similar Chinese medicine herbal formulae
- Chinese Journal of Integrative Medicine Vol. 17, Issue 12, Pages: 903-907(2011)
- Affiliations：
  
  1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences,Beijing,China
  2. Peking University First Hospital,Beijing,China
  3. Institute of Shanghai Municipal Education Commission, Shanghai University of Traditional Chinese Medicine, Shanghai,E,China
- Author bio：
- Funds：
  
  Supported in Part by Projects from National Science Foundation of China (No. 90209002 and 30825047), and E-Institutes of Shanghai Municipal Education Commission (No. E03008)
- DOI：10.1007/s11655-011-0933-6
  CLC：
- Published：2011，
  
  Published Online：3 December 2011，
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Yan, Sy., Yao, C., Ding, Xr. et al. Serum low-density lipoprotein and heart rate related to the effectiveness in the treatment of angina pectoris with two similar Chinese medicine herbal formulae., Chin. J. Integr. Med. 17, 903–907 (2011). https://doi.org/10.1007/s11655-011-0933-6

Shi-yan Yan, Chen Yao, Xiao-rong Ding, et al. Serum low-density lipoprotein and heart rate related to the effectiveness in the treatment of angina pectoris with two similar Chinese medicine herbal formulae. [J]. Chinese Journal of Integrative Medicine 17(12):903-907(2011)
Yan, Sy., Yao, C., Ding, Xr. et al. Serum low-density lipoprotein and heart rate related to the effectiveness in the treatment of angina pectoris with two similar Chinese medicine herbal formulae., Chin. J. Integr. Med. 17, 903–907 (2011). https://doi.org/10.1007/s11655-011-0933-6 DOI：

Shi-yan Yan, Chen Yao, Xiao-rong Ding, et al. Serum low-density lipoprotein and heart rate related to the effectiveness in the treatment of angina pectoris with two similar Chinese medicine herbal formulae. [J]. Chinese Journal of Integrative Medicine 17(12):903-907(2011) DOI： 10.1007/s11655-011-0933-6.

摘要

To explore the effectiveness related indicators which might help identify the indications of Tongxinluo Capsule (通心络胶囊) and Kangxin Capsule (康欣胶囊) targeting on qi deficiency and blood stasis pattern in Chinese medicine (CM) in the treatment of angina pectoris. The data from a multicenter

randomized and double-blinded study conducted at 5 centers in China were obtained for the analysis. A total of 239 patients with angina pectoris and CM syndrome of qi deficiency and blood stasis were randomly assigned in a 1:1 ratio to Tongxinluo Capsule group (119 cases) and Kangxin Capsule group (120 cases). Angina effectiveness and electrocardiogram (ECG) improvement were selected as the therapeutic outcomes. After a 4-week treatment

the effective rates of Tongxinluo Capsule and Kangxin Capsule were 43.70% and 25.00%

respectively (P <0.05). Serum low-density lipoprotein (LDL) level was found to influence the effectiveness of Tongxinluo Capsule which had higher effective rate in the patients with lower level of LDL. Heart rate was found to influence the effectiveness in the patients treated with Kangxin Capsule which had higher effective rate in the patients with heart rate ⩽80 beats/min. LDL level and heart rate were the indicators which help indentify the indications of Tongxinluo Capsule and Kangxin Capsule

respectively

in the treatment of angina pectoris with CM syndrome of qi deficiency and blood stasis.

Abstract

the effective rates of Tongxinluo Capsule and Kangxin Capsule were 43.70% and 25.00%

respectively

in the treatment of angina pectoris with CM syndrome of qi deficiency and blood stasis.

关键词

angina pectorisqi deficiency and blood stasis syndromeChinese Medicinelow-density lipoproteinHeart Rate

Keywords

angina pectorisqi deficiency and blood stasis syndromeChinese Medicinelow-density lipoproteinHeart Rate

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