Effectiveness of Bufei Yishen Granule (补肺益肾颗粒) combined with acupoint sticking therapy on quality of life in patients with stable chronic obstructive pulmonary disease

Yang Xie; Jian-sheng Li; Xue-qing Yu; Su-yun Li; Nian-zhi Zhang; Ze-geng Li; Su-ju Shao; Lian-xiang Guo; Lin Zhu; Yi-jie Zhang

doi:10.1007/s11655-013-1438-2

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Effectiveness of Bufei Yishen Granule (补肺益肾颗粒) combined with acupoint sticking therapy on quality of life in patients with stable chronic obstructive pulmonary disease

Updated：2021-08-27

- Effectiveness of Bufei Yishen Granule (补肺益肾颗粒) combined with acupoint sticking therapy on quality of life in patients with stable chronic obstructive pulmonary disease
- Chinese Journal of Integrative Medicine Vol. 19, Issue 4, Pages: 260-268(2013)
- Affiliations：
  
  1. Dongzhimen Hospital, Beijing University of Chinese Medicine,Beijing,China
  2. The Geriatric Department, Henan University of Traditional Chinese Medicine,Zhengzhou,China
  3. Department of Respiratory, the First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou,China
  4. Department of Respiratory, the First Affiliated Hospital of Anhui College of Traditional Chinese Medicine,Hefei,China
  5. Department of Acupuncture and Moxibustion, the Third Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou,China
  6. Department of Respiratory, the Second People’s Hospital of Jiaozuo City,Henan,Jiaozuo,China
  7. Department of Respiratory, Kaifeng Hospital of Traditional Chinese Medicine,Henan,Kaifeng,China
  8. Department of Respiratory, Huaihe Hospital of Henan University,Henan,Kaifeng,China
- Author bio：
- Funds：
  
  Supported by the Specific Research in Traditional Chinese Medicine Industry of State Administration of Traditional Chinese Medicine (No. 200707018)
- DOI：10.1007/s11655-013-1438-2
  CLC：
- Published：2013，
  
  Published Online：2 April 2013，
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Xie, Y., Li, Js., Yu, Xq. et al. Effectiveness of Bufei Yishen Granule (补肺益肾颗粒) combined with acupoint sticking therapy on quality of life in patients with stable chronic obstructive pulmonary disease., Chin. J. Integr. Med. 19, 260–268 (2013). https://doi.org/10.1007/s11655-013-1438-2

Yang Xie, Jian-sheng Li, Xue-qing Yu, et al. Effectiveness of Bufei Yishen Granule (补肺益肾颗粒) combined with acupoint sticking therapy on quality of life in patients with stable chronic obstructive pulmonary disease. [J]. Chinese Journal of Integrative Medicine 19(4):260-268(2013)
Xie, Y., Li, Js., Yu, Xq. et al. Effectiveness of Bufei Yishen Granule (补肺益肾颗粒) combined with acupoint sticking therapy on quality of life in patients with stable chronic obstructive pulmonary disease., Chin. J. Integr. Med. 19, 260–268 (2013). https://doi.org/10.1007/s11655-013-1438-2 DOI：

Yang Xie, Jian-sheng Li, Xue-qing Yu, et al. Effectiveness of Bufei Yishen Granule (补肺益肾颗粒) combined with acupoint sticking therapy on quality of life in patients with stable chronic obstructive pulmonary disease. [J]. Chinese Journal of Integrative Medicine 19(4):260-268(2013) DOI： 10.1007/s11655-013-1438-2.

摘要

To evaluate the efficacy of Bufei Yishen Granule (补肺益肾颗粒

BFYSG) combined with Shufei Tie (舒肺贴) acupoint sticking therapy on quality of life of patients with stable chronic obstructive pulmonary disease (COPD). A multi-center

double-blinded

double-dummy and randomized controlled method was adopted in this trial. A total of 244 patients were randomly assigned to a trial group and a control group according to the random number

each with 122 patients; treatment allocation occurred when the participants met the inclusion criteria and signed the informed consent form. In the trial group

patients were treated with BFYSG combined with “Shufei Tie” acupoint sticking therapy and sustained-release theophylline dummy

and in the control group patients were treated with oral sustained-release theophylline and BFYSG dummy combined with “Shufei Tie” acupoint sticking therapy dummy. The therapeutic course for two groups was 4 months and the follow-up was 6 months. The frequency and duration of acute exacerbation calculated by adding up each frequency and duration of acute exacerbation in treatment and follow-up time respectively

the quality of life measured by the World Health Organization Quality of Life (WHOQOL)-BREF scale and adult COPD quality of life (COPD-QOL) scale were observed. Among the 244 enrolled patients

234 were screened for full analysis set (FAS); 221 were screened for per-protocol analysis set (PPS). After 4-month treatment and 6-month follow-up there were differences between the trial group and the control group in frequency of acute exacerbation (FAS: P=0.013; PPS: P=0.046); duration of acute exacerbation (FAS: P=0.005; PPS: P=0.006); scores of physiological

psychological and environment aspects of the WHOQOL-BREF questionnaire (FAS: P=0.002

P=0.006

P=0.000; PPS: P=0.00

P=0.001

P=0.000); scores of daily living ability

social activity

depression symptoms aspects of the COPD-QOL questionnaire (FAS: P=0.000

P=0.000

P=0.006; PPS: P=0.002

P=0.001

P=0.001). BFYSG combined with acupoint sticking therapy could improve the quality of life of patients with stable COPD.

Abstract

To evaluate the efficacy of Bufei Yishen Granule (补肺益肾颗粒

BFYSG) combined with Shufei Tie (舒肺贴) acupoint sticking therapy on quality of life of patients with stable chronic obstructive pulmonary disease (COPD). A multi-center

double-blinded

double-dummy and randomized controlled method was adopted in this trial. A total of 244 patients were randomly assigned to a trial group and a control group according to the random number

each with 122 patients; treatment allocation occurred when the participants met the inclusion criteria and signed the informed consent form. In the trial group

patients were treated with BFYSG combined with “Shufei Tie” acupoint sticking therapy and sustained-release theophylline dummy

the quality of life measured by the World Health Organization Quality of Life (WHOQOL)-BREF scale and adult COPD quality of life (COPD-QOL) scale were observed. Among the 244 enrolled patients

psychological and environment aspects of the WHOQOL-BREF questionnaire (FAS: P=0.002

P=0.006

P=0.000; PPS: P=0.00

P=0.001

P=0.000); scores of daily living ability

social activity

depression symptoms aspects of the COPD-QOL questionnaire (FAS: P=0.000

P=0.000

P=0.006; PPS: P=0.002

P=0.001

P=0.001). BFYSG combined with acupoint sticking therapy could improve the quality of life of patients with stable COPD.

关键词

Chinese MedicineChronic Obstructive Pulmonary DiseaseBufei Yishen Granuleacupoint sticking therapyquality of life

Keywords

Chinese MedicineChronic Obstructive Pulmonary DiseaseBufei Yishen Granuleacupoint sticking therapyquality of life

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