Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization

Yong-qiang Li; Mei Jin; Sheng-lei Qiu; Pei-li Wang; Tian-gang Zhu; Cheng-long Wang; Tian-chang Li; Hong-xu Liu; Hong Bian; Li-fang Yao; Da-zhuo Shi

doi:10.1007/s11655-009-0019-7

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Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization

OriginalPaper | Updated：2021-08-27

- Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization
- Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization
- 中国结合医学杂志（英文版） 2009年15卷第1期页码：19-25
- Affiliations：
  
  1. Cardiovascular Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Department of Internal Cardiac Medicine, Beijing Hospital of Traditional Chinese Medicine Affiliated to the Capital Medical University,Beijing,China
  3. Department of Internal Cardiac Medicine, the People’s Hospital of Peking University,Beijing,China
  4. Department of Internal Cardiac Medicine, Tongren Hospital Affiliated to the Capital Medical University,Beijing,China
- Author bio：
- Funds：
  
  Supported by the National Key Technologies Research and Development Program of China during the 10th Five-Year Plan Period (No. 2003BA712A11)
- DOI：10.1007/s11655-009-0019-7
  中图分类号：
- 纸质出版日期：2009，
  
  网络出版日期：2009-3-7，
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Li, Yq., Jin, M., Qiu, Sl. et al. Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization., Chin. J. Integr. Med. 15, 19–25 (2009). https://doi.org/10.1007/s11655-009-0019-7

Yong-qiang Li, Mei Jin, Sheng-lei Qiu, et al. Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization[J]. Chinese Journal of Integrative Medicine, 2009,15(1):19-25.
Li, Yq., Jin, M., Qiu, Sl. et al. Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization., Chin. J. Integr. Med. 15, 19–25 (2009). https://doi.org/10.1007/s11655-009-0019-7 DOI：

Yong-qiang Li, Mei Jin, Sheng-lei Qiu, et al. Effect of Chinese drugs for supplementing qi, Nourishing Yin and activating blood circulation on myocardial perfusion in patients with acute myocardial infarction after revascularization[J]. Chinese Journal of Integrative Medicine, 2009,15(1):19-25. DOI： 10.1007/s11655-009-0019-7.

摘要

To observe the effects of Chinese drugs for supplementing qi

nourishing yin and activating blood circulation on the myocardial perfusion in acute myocardial infarction (AMI) patients after revascularization. Eighty patients with anterior or inferior ventricular wall AMI

who had received revascularization by intravenous thrombolysis or coronary bypass

were randomized into the treated group and the control group equally

both treated with conventional Western medical treatment

but combined

respectively

with Xinyue Capsule (心悦胶囊

XYC) plus Composite Salvia Tablet (CST) and placebo for 3 months. Dobutamine stress echocardiography (DSE) was performed 14 days and 3 months after revascularization

respectively on every patient to observe blood perfusion extent (b value)

myocardial perfusion velocity (k value) and local blood fl ow volume (k × b) in left ventricular infarction-related vascular segments under stressed state. With 5 cases dropping out in the observation period (3 in the treated group and 2 in the control group)

the trial was completed in 75 patients in total. The 14-day DSE shows that the b value and k × b value of left anterior ventricular wall mid segment and apex segment

and the k value of apex segment in patients with anterior wall AMI

as well as the b value and k × b of basal segment in patients with inferior wall AMI in the treated group were significantly higher than those in the control group (P<0.05 or P<0.01). The 3-month DSE shows that the b value of apex segment

k × b value of basal segment

mid segment and apex segment of left anterior ventricular wall in patients with anterior wall AMI as well as the b value and k × b value of basal segment of left inferior ventricular wall in patients with inferior wall AMI were all higher in the treated group than those in the control group

respectively (P<0.05). The comparison between 14-day DSE and 3-month DSE in the treated group showed that the b value of apex segment of left anterior ventricular wall in patients with anterior wall AMI and the k × b value of apex segment and mid segment of left inferior ventricular wall in patients with inferior wall AMI significantly increased along with the on-going treatment (P<0.05). Therapy with Chinese drugs for supplementing qi

nourishing yin and activating blood circulation in combination with conventional Western medical treatment could obviously improve the blood perfusion at the myocardial tissue level in infarction-related vascular segments.

Abstract

To observe the effects of Chinese drugs for supplementing qi

who had received revascularization by intravenous thrombolysis or coronary bypass

were randomized into the treated group and the control group equally

both treated with conventional Western medical treatment

but combined

respectively

with Xinyue Capsule (心悦胶囊

XYC) plus Composite Salvia Tablet (CST) and placebo for 3 months. Dobutamine stress echocardiography (DSE) was performed 14 days and 3 months after revascularization

respectively on every patient to observe blood perfusion extent (b value)

the trial was completed in 75 patients in total. The 14-day DSE shows that the b value and k × b value of left anterior ventricular wall mid segment and apex segment

and the k value of apex segment in patients with anterior wall AMI

k × b value of basal segment

关键词

Chinese drugs for supplementing qinourishing yin and activating blood circulationacute myocardial infarctionblood circulation rebuildingmyocardial perfusionDoppler’s ultrasonic acoustic photography

Keywords

Chinese drugs for supplementing qinourishing yin and activating blood circulationacute myocardial infarctionblood circulation rebuildingmyocardial perfusionDoppler’s ultrasonic acoustic photography

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