Tanshinone IIA: a potent, natural anti-carcinogenic agent for the management of systemic malignancies

Shailendra Kapoor

doi:10.1007/s11655-009-0153-5

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Tanshinone IIA: a potent, natural anti-carcinogenic agent for the management of systemic malignancies

OriginalPaper | Updated：2021-08-27

- Tanshinone IIA: a potent, natural anti-carcinogenic agent for the management of systemic malignancies
- Tanshinone IIA: a potent, natural anti-carcinogenic agent for the management of systemic malignancies
- 中国结合医学杂志（英文版） 2009年15卷第2期页码：153
- Affiliations：
  
  University of Illinois at Chicago,Chicago,USA
- Author bio：
- Funds：
- DOI：10.1007/s11655-009-0153-5
  中图分类号：
- 纸质出版日期：2009，
  
  网络出版日期：2009-4-29，
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Kapoor, S. Tanshinone IIA: a potent, natural anti-carcinogenic agent for the management of systemic malignancies., Chin. J. Integr. Med. 15, 153 (2009). https://doi.org/10.1007/s11655-009-0153-5

Shailendra Kapoor. Tanshinone IIA: a potent, natural anti-carcinogenic agent for the management of systemic malignancies[J]. Chinese Journal of Integrative Medicine, 2009,15(2):153.
Kapoor, S. Tanshinone IIA: a potent, natural anti-carcinogenic agent for the management of systemic malignancies., Chin. J. Integr. Med. 15, 153 (2009). https://doi.org/10.1007/s11655-009-0153-5 DOI：

Shailendra Kapoor. Tanshinone IIA: a potent, natural anti-carcinogenic agent for the management of systemic malignancies[J]. Chinese Journal of Integrative Medicine, 2009,15(2):153. DOI： 10.1007/s11655-009-0153-5.

摘要

Abstract

关键词

Acute Promyelocytic LeukemiaGinsenosideTanshinoneAcute Promyelocytic Leukemia CellHuman Gastric Carcinoma Cell

Keywords

Acute Promyelocytic LeukemiaGinsenosideTanshinoneAcute Promyelocytic Leukemia CellHuman Gastric Carcinoma Cell

references

Li SS, Feng J, Zheng Z, Liang QS. Effect of sodium tanshinone IIA sulfonate on phosphorylation of extracellular signalregulated kinase 1/2 in angiotensin II-induced hypertrophy of myocardial cells. Chin J Integr Med 2008;14:123–127.

Wang X, Wei Y, Yuan S, Liu G, Lu Y, Zhang J, et al. Potential anticancer activity of tanshinone IIA against human breast cancer. Int J Cancer 2005;116:799–807.

Dong X, Dong J, Peng G. Growth-inhibiting and apoptosis-inducing effects of tanshinone IIA on human gastric carcinoma cells. J Huazhong Univ Sci Technol Med Sci (Chin) 2007;27:706–709.

Efferth T, Kahl S, Paulus K, Adams M, Rauh R, Boechzelt H, et al. Phytochemistry and pharmacogenomics of natural products derived from traditional Chinese medicine and Chinese materia medica with activity against tumor cells. Mol Cancer Ther 2008;7:152–161.

Liu JJ, Lin DJ, Liu PQ, Huang M, Li XD, Huang RW. Induction of apoptosis and inhibition of cell adhesive and invasive effects by tanshinone IIA in acute promyelocytic leukemia cells in vitro. J Biomed Sci 2006;13:813–823.

Zhang HH, Chen YC, Liang L, Zeng Z. Tanshinone II A inhibits in vitro cellular proliferation and migration of vascular smooth muscle cells of rabbits. J Sichuan Univ (Med Sci Edit, Chin) 2008;39:188–192.

Li QF, Shi SL, Liu QR, Tang J, Song J, Liang Y. Anticancer effects of ginsenoside Rg1, cinnamic acid, and tanshinone IIA in osteosarcoma MG-63 cells: nuclear matrix downregulation and cytoplasmic trafficking of nucleophosmin. Int J Biochem Cell Biol 2008;40:1918–1929.

Lee WY, Chiu LC, Yeung JH. Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation. Food Chem Toxicol 2008;46:328–338.

Zhong ZH, Chen WG, Liu YH, Li QX, Qiu Y. Inhibition of cell growth and induction of apoptosis in human hepatoma cell line HepG2 by tanshione IIA. J Central South Univ (Med Sci Edit, Chin) 2007;32:99–103.

Guo WQ, Xu WJ, Wang T, Chang JL, Chen MJ, He GY. Tanshinone II-A, a putative modulator can regulate pro-inflammatory and anti-inflammatory cytokines in inflammatory conditions in RAW264.7 cells. Biomedicine & Pharmacotherapy Available online 11 July 2008.

Xu Y, Feng D, Wang Y, Lin S, Xu L. Sodium tanshinone II, a sulfonate protects mice from ConA-induced hepatitis via inhibiting NF-kappaB and IFN-gamma/STAT1 pathways. J Clin Immunol 2008; 28:512–519.

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