穴位埋线疗法的安全性系统评价

Jia-jia HUANG; Jun-quan LIANG; Xiao-kang XU; Yun-xiang XU; Gui-zhen CHEN

doi:10.1007/s11655-021-3443-1

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穴位埋线疗法的安全性系统评价

Evidence-Based Integrative Medicine | Updated：2021-11-29

- 穴位埋线疗法的安全性系统评价
- Safety of Thread Embedding Acupuncture Therapy:A Systematic Review^*
- Chinese Journal of Integrative Medicine 2021年27卷第12期页码：947-955
- Affiliations：
  
  1.Clinical Medical School of Acupuncture, Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine,Guangzhou (510405), China
  2.Shenzhen Bao'an Traditional Chinese Medicine Hospital, The Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Shenzhen, Guangdong Province (518101), China
- Author bio：
  
  Dr. XU Yun-xiang, E-mail: xuyx1968@163.com;
  Dr. CHEN Gui-zhen, E-mail: cgzhen2000@163.com
- Funds：
  
  the National Natural Science Foundation of China(81574064;81473755);Shenzhen Science and Technology Planning Project(JCYJ20170306152650625);Shenzhen Bao'an Traditional Chinese Medicine Hospital Research Program(BAZYY20200609)
- DOI：10.1007/s11655-021-3443-1
  中图分类号：
- 纸质出版日期：2021-11-15，
  
  网络出版日期：2021-04-24，
  
  录用日期：2020-12-25
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Jia-jia HUANG, Jun-quan LIANG, Xiao-kang XU, 等. 穴位埋线疗法的安全性系统评价[J]. Chinese Journal of Integrative Medicine, 2021,27(12):947-955.

Jia-jia HUANG, Jun-quan LIANG, Xiao-kang XU, et al. Safety of Thread Embedding Acupuncture Therapy:A Systematic Review^*[J]. Chinese Journal of Integrative Medicine, 2021,27(12):947-955.
Jia-jia HUANG, Jun-quan LIANG, Xiao-kang XU, 等. 穴位埋线疗法的安全性系统评价[J]. Chinese Journal of Integrative Medicine, 2021,27(12):947-955. DOI： 10.1007/s11655-021-3443-1.

Jia-jia HUANG, Jun-quan LIANG, Xiao-kang XU, et al. Safety of Thread Embedding Acupuncture Therapy:A Systematic Review^*[J]. Chinese Journal of Integrative Medicine, 2021,27(12):947-955. DOI： 10.1007/s11655-021-3443-1.

摘要

目的:

评价穴位埋线疗法 (TEAT) 的安全性并讨论不良事件 (AEs) 的预防和治疗.

方法:

检索中国知网 (CNKI) 、CBMdisc、万方、VIP

以及PubMed、MEDLINE、EMBASE和Web of Science 上报告AE的TEAT相关随机对照试验 (RCTs) 和病例报告

检索时间为从建库开始至 2020年1月. 采用Cochrane Collaboration 工具和 RevMan V.5.3.3 软件评估研究质量.

结果:

共纳入中国和韩国发表的61项研究

总结了28种AEs

最常见的 AE 包括硬结、出血和瘀斑、红肿、发烧

以及疼痛

占报告总数的75.35% (425/564)

多为轻度. 罕见的AE 包括癫痫、月经不调、皮肤溃疡、线吸收不良和脂肪液化

各 1 例

但并非均与 TEAT 有明确因果关系. 大多数AE为局部反应

发生率为9.83% (480/4

882)

全身反应仅占1.27% (62/4

882). 虽然纳入的研究显示AEs非常常见 (11.09%)

但2013年至2017年仅有5例 (0.1%) 使用肠线的研究报告了严重AEs

随着新型可吸收手术缝合线的广泛使用

现已很少见. 所有严重AE经对症治疗后均痊愈

无后遗症.

结论:

证据表明 TEAT 是一种相对安全和方便的治疗方法

尤其在新型可吸收手术缝线的广泛应用后. 提高操作者技能、规范操作、关注患者病情可以降低AE发生率

提高TEAT的安全性.

Abstract

Objective:

To evaluate the safety of thread embedding acupuncture therapy (TEAT) and discuss the prevention and treatment of some adverse events (AEs).

Methods:

Review of databases

including China National Knowledge Infrastructure (CNKI)

CBMdisc

Wanfang

VIP databases and English literature published in PubMed

MEDLINE

EMBASE and Web of Science

were searched from their inception to January 2020

randomized controlled trials (RCTs) and case reports in which AEs with TEAT were included. Cochrane Collaboration's tool and RevMan V.5.3.3 software were used to evaluate the quality of the studies.

Results:

A total of 61 studies (45 RCTs and 16 case reports) with 620 cases of AEs were included in this review. These studies were published in two countries: China and South Korea. Twenty eight kinds of AEs were summarized. The most common AEs were induration

bleeding and ecchymosis

redness and swelling

fever

and pain. They were accounted for 75.35% (425/564) in the review

and most of them were mild. The rarest AEs were epilepsy

irregular menstruation

skin ulcer

thread malabsorption

and fat liquefaction

with 1 case each. But not all of them had clear causal relationship with TEAT. Most of the AEs were local reactions [with incidence of 9.83% (480/4

882) ] and systemic reactions accounted for only 1.27% (62/4

882). Although the included studies showed that AEs were very commonly encountered (11.09%)

only 5 cases of severe AEs reported from 2013 to 2017 (0.1%) by using catgut thread

which are rarely seen nowdays with the wide use of new absorbable surgical suture. All of the severe AEs were recovered after symptomatic treatment with no sequelae.

Conclusions:

The evidence showed that TEAT is a relatively safe and convenient therapy especially since application of new absorbable surgical suture. Improving practitioner skills

regulating operations

and paying attention to the patients' conditions may reduce the incidence of AEs and improve safety of TEAT.

关键词

Keywords

thread embedding acupuncturesystematic reviewsafetyadverse eventsChinese Medicine

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