Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome

Yu Su-ping; Ye Hui; Ha Nan-lin; Ding Shu-qing; Chen Gao

doi:10.1007/BF02835744

Your Location：

Home >

Browse articles >

Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome

Updated：2021-08-27

- Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome
- Chinese Journal of Integrative Medicine Vol. 11, Issue 1, Pages: 27-30(2005)
- Affiliations：
  
  Anorectal Department, Nanjing Municipal TCM Hospital,Nanjing
- Author bio：
- Funds：
- DOI：10.1007/BF02835744
  CLC：
- Published：2005，
Scan for full text
Su-ping, Y., Hui, Y., Nan-lin, H. et al. Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome., Chin. J. Integr. Med. 11, 27–30 (2005). https://doi.org/10.1007/BF02835744

Yu Su-ping, Ye Hui, Ha Nan-lin, et al. Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome. [J]. Chinese Journal of Integrative Medicine 11(1):27-30(2005)
Su-ping, Y., Hui, Y., Nan-lin, H. et al. Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome., Chin. J. Integr. Med. 11, 27–30 (2005). https://doi.org/10.1007/BF02835744 DOI：

Yu Su-ping, Ye Hui, Ha Nan-lin, et al. Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome. [J]. Chinese Journal of Integrative Medicine 11(1):27-30(2005) DOI： 10.1007/BF02835744.

摘要

Objective: To explore the mechanism in patients with irritable bowel syndrome (IBS) of the constipation predominant type and observe the therapeutic effects of Sinisan (SNS).Methods: Forty-seven IBS patients with the constipation predominant type were randomly divided into the treated group (n = 24) and the control group (n = 23). Another group of 22 healthy subjects was set up for healthy control. The treated group was treated with modified SNS

and the control group was treated with Cisapride

the therapeutic course for both groups was 8 weeks. The changes of symptom scoring and anorectal manometry (the anorectal resting pressure

anal tract systolic pressure

anal tract diastolic pressure

rectal threshold feeling

maximal tolerance volume of rectum

and rectum compliance) of these two groups were recorded respectively and compared with each other.Results: Compared with the healthy control group

the rectal threshold feeling

maximal tolerance volume of rectum and rectal compliance of the treated groups got reduced significantly before treatment (P<0.05). After treatment

the symptom scoring

rectal threshold feeling and maximal tolerance volume of rectum were improved in both groups (P<0.05)

and the improvement of the treated group was more significant than that of the control group(P<0. 01). The total effective rate and recurrence rate of the treated group were superior to those of the control group significantly (P<0.05

P<0.01).Conclusion: SNS has good effect on IBS of the constipation predominant type.

Abstract

and the control group was treated with Cisapride

the therapeutic course for both groups was 8 weeks. The changes of symptom scoring and anorectal manometry (the anorectal resting pressure

anal tract systolic pressure

anal tract diastolic pressure

rectal threshold feeling

maximal tolerance volume of rectum

and rectum compliance) of these two groups were recorded respectively and compared with each other.Results: Compared with the healthy control group

the rectal threshold feeling

maximal tolerance volume of rectum and rectal compliance of the treated groups got reduced significantly before treatment (P<0.05). After treatment

the symptom scoring

rectal threshold feeling and maximal tolerance volume of rectum were improved in both groups (P<0.05)

P<0.01).Conclusion: SNS has good effect on IBS of the constipation predominant type.

关键词

Irritable Bowel Syndromeconstipation-predominant typeAnorectal ManometrySinisan

Keywords

Irritable Bowel Syndromeconstipation-predominant typeAnorectal ManometrySinisan

references

Thompson WG. The Road to Rome. Gut 1999; 45 (Supl II): II 80.

Wei BH. TCM syndrome differentiation and treatment of GI motility disturbances disorder. Chin J CWM Diges 2003;11(5): 259.

Camilleri M, Prsather CM. The irritable bowel syndrome: mechanisms and a practical approach to management. Ann Intern Med 1992;116(12): 1001.

Shen YJ. Chinese drugs pharmacology. Beijing: People’s Medical Publishing House, 2000: 547,632,1072.

FULL TEXT LINK

More>

Views

364

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Irritable bowel syndrome: Common integrative medicine perspectives

Thinking and strategy on the diagnosis and treatment of functional gastrointestinal disorders with integrative medicine

Traditional Chinese medicine clinical experience of the treatment for irritable bowel syndrome

Effect of Shugan Jianpi Granule (舒肝健脾颗粒) on gut mucosal serotonin-positive cells in patients with irritable bowel syndrome of stagnated Gan-qi attacking Pi syndrome type

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Related Author

No data

Related Institution

Seekers Centre for Integrative Medicine

Digestive Disease Center, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University

Department of Gastroenterology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Institute of Digestive Disease, Shanghai University of Traditional Chinese Medicine

Department of Digestive Medicine, Dongfang Hospital Affiliated to Beijing University of Chinese Medicine

Department of Digestive Medicine, the Third Hospital Affiliated to Beijing University of Chinese Medicine

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰