Follow-up efficacy of integrative Chinese and Western drugs on localized scleroderma with vitamine B6 and Xuefu Zhuyu Decoction

Wang Wen-ling; Su You-ming; Yang Rong-ya; Zhang Jie; Xu Yang

doi:10.1007/BF02835746

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Follow-up efficacy of integrative Chinese and Western drugs on localized scleroderma with vitamine B6 and Xuefu Zhuyu Decoction

Updated：2021-08-27

- Follow-up efficacy of integrative Chinese and Western drugs on localized scleroderma with vitamine B6 and Xuefu Zhuyu Decoction
- Chinese Journal of Integrative Medicine Vol. 11, Issue 1, Pages: 34-36(2005)
- Affiliations：
  
  Department of Dermatology, General Hospital of Beijing Military Region,Beijing
- Author bio：
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- DOI：10.1007/BF02835746
  CLC：
- Published：2005，
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Wen-ling, W., You-ming, S., Rong-ya, Y. et al. Follow-up efficacy of integrative Chinese and Western drugs on localized scleroderma with vitamine B6 and Xuefu Zhuyu Decoction., Chin. J. Integr. Med. 11, 34–36 (2005). https://doi.org/10.1007/BF02835746

Wang Wen-ling, Su You-ming, Yang Rong-ya, et al. Follow-up efficacy of integrative Chinese and Western drugs on localized scleroderma with vitamine B6 and Xuefu Zhuyu Decoction. [J]. Chinese Journal of Integrative Medicine 11(1):34-36(2005)
Wen-ling, W., You-ming, S., Rong-ya, Y. et al. Follow-up efficacy of integrative Chinese and Western drugs on localized scleroderma with vitamine B6 and Xuefu Zhuyu Decoction., Chin. J. Integr. Med. 11, 34–36 (2005). https://doi.org/10.1007/BF02835746 DOI：

Wang Wen-ling, Su You-ming, Yang Rong-ya, et al. Follow-up efficacy of integrative Chinese and Western drugs on localized scleroderma with vitamine B6 and Xuefu Zhuyu Decoction. [J]. Chinese Journal of Integrative Medicine 11(1):34-36(2005) DOI： 10.1007/BF02835746.

摘要

Objective: To investigate the therapeutic effects of vitamine B6 (Vit B6) and Xuefu Zhuyu Decoction (XFZY

for activating blood circulation to remove stasis) in patients with localized scleroderma(LSD).Methods: Thirty-three patients were treated with XFZY and Vit B6

with 15 cases taking orally prednisone acetate and 20 healthy volunteers as the control. Their level of soluble interleukin-2 receptor (sIL-2R) and tumor necrosis factor-α (TNF-α) in the patients with LSD before and after treatment were observed.Results: The level of sIL-2R and TNF-α in the serum from the patients with LSD were higher than those of healthy volunteers (P<0.01). After treatment with Vit B6 and XFZY

the level of sIL-2R and TNF-α from the patients with LSD decreased significantly (P<0.01)

but there were no difference between the group taking Vit B6 plus XFZY and the group given prednisone.Conclusion: The activating blood circulation to remove stasis approach in treating LSD with integrative Chinese and Western drugs got better results

and metabolic disorder of tryptophan might be correlated with the etiology of LSD.

Abstract

Objective: To investigate the therapeutic effects of vitamine B6 (Vit B6) and Xuefu Zhuyu Decoction (XFZY

for activating blood circulation to remove stasis) in patients with localized scleroderma(LSD).Methods: Thirty-three patients were treated with XFZY and Vit B6

the level of sIL-2R and TNF-α from the patients with LSD decreased significantly (P<0.01)

and metabolic disorder of tryptophan might be correlated with the etiology of LSD.

关键词

localized sclerodermaintegrative Chinese and Western drugsfollow-up of efficacy

Keywords

localized sclerodermaintegrative Chinese and Western drugsfollow-up of efficacy

references

Zhao B editor. Clinical dermatology. 2nd ed. Nanjing: Jiangsu Science and Technology Press, 1989: 587.

Peng XB. An index of LSD, sIL-2R level. For Med: Derm STD Fasc 1995;21(4): 241.

Zhang W. The pathogenic and clinical significance of tryptophan. For Med: Derm STD Fasc 1993;19(2): 81–88.

Sun CX editor. Diagnostic standard of cured and improvement of clinical diseases. 2nd ed. Beijing: People’s Military Medical Press, 1987: 296.

Su YM, Yu M, Yan F, et al. sIL-2R, TNF-α level and lymphocyte subset determination in LSD. Clin J Dermatol 1998: 22(1): 5.

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