Effects of Jiantaiye on estrogen receptor and mRNA expressions in uterus of mice with embryo implantation dysfunction

Liu Yan-juan; Huang Guang-ying; Yang Ming-wei; Gong ping; Zhang Ming-min; Lu Fu-er

doi:10.1007/BF02835748

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Effects of Jiantaiye on estrogen receptor and mRNA expressions in uterus of mice with embryo implantation dysfunction

Updated：2021-08-27

- Effects of Jiantaiye on estrogen receptor and mRNA expressions in uterus of mice with embryo implantation dysfunction
- Chinese Journal of Integrative Medicine Vol. 11, Issue 1, Pages: 41-44(2005)
- Affiliations：
  
  Department of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 30171193)
- DOI：10.1007/BF02835748
  CLC：
- Published：2005，
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Yan-juan, L., Guang-ying, H., Ming-wei, Y. et al. Effects of Jiantaiye on estrogen receptor and mRNA expressions in uterus of mice with embryo implantation dysfunction., Chin. J. Integr. Med. 11, 41–44 (2005). https://doi.org/10.1007/BF02835748

Liu Yan-juan, Huang Guang-ying, Yang Ming-wei, et al. Effects of Jiantaiye on estrogen receptor and mRNA expressions in uterus of mice with embryo implantation dysfunction. [J]. Chinese Journal of Integrative Medicine 11(1):41-44(2005)
Yan-juan, L., Guang-ying, H., Ming-wei, Y. et al. Effects of Jiantaiye on estrogen receptor and mRNA expressions in uterus of mice with embryo implantation dysfunction., Chin. J. Integr. Med. 11, 41–44 (2005). https://doi.org/10.1007/BF02835748 DOI：

Liu Yan-juan, Huang Guang-ying, Yang Ming-wei, et al. Effects of Jiantaiye on estrogen receptor and mRNA expressions in uterus of mice with embryo implantation dysfunction. [J]. Chinese Journal of Integrative Medicine 11(1):41-44(2005) DOI： 10.1007/BF02835748.

摘要

Objective: To explore the effect of Jiantaiye (JTY) on the expression of estrogen receptor (ER) and ER mRNA in uterus of mice with embryo implantation dysfunction.Methods: Embryo implantation dysfunction mouse models were induced with mifepristone and treated with JTY. All animals were sacrificed on day 8 of pregnancy. The endometrial ER and ER mRNA expressions were assessed by immunno-histochemical SP method and semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR).Results: Area ratio and absorbency of ER in the JTY treated group’s gland and stroma were higher than those of the model group

quite similar to those of the normal control’s

and ER mRNA expression in treated group’s uterus was significantly higher than that in the models

but it was not significantly different from the normal control.Conclusion: JTY improves the endometrial development by increasing ER and ER mRNA expressions of uterus of mice with embryo implantation dysfunction.

Abstract

quite similar to those of the normal control’s

and ER mRNA expression in treated group’s uterus was significantly higher than that in the models

关键词

Jiantaiyeembryo implantationestrogen receptor

Keywords

Jiantaiyeembryo implantationestrogen receptor

references

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Key Laboratory of Internal Medicine, Hunan University of Traditional Chinese Medicine

Department of Obstetrics and Gynecology, The First Hospital, Shanxi Medical University

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Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital Institute

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