Study of the effect of leeching on plasma endothelin and soluble interleukin-2 receptor in patients with systemic lupus erythematosus

Cheng Shi-ping; Liu Jia-lin; Yuan Jing

doi:10.1007/BF02835754

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Study of the effect of leeching on plasma endothelin and soluble interleukin-2 receptor in patients with systemic lupus erythematosus

Updated：2021-08-27

- Study of the effect of leeching on plasma endothelin and soluble interleukin-2 receptor in patients with systemic lupus erythematosus
- Chinese Journal of Integrative Medicine Vol. 11, Issue 1, Pages: 65-68(2005)
- Affiliations：
  
  Nephrology Department, People’s Hospital of Guizhou Province,Guiyang
- Author bio：
- Funds：
- DOI：10.1007/BF02835754
  CLC：
- Published：2005，
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Shi-ping, C., Jia-lin, L. & Jing, Y. Study of the effect of leeching on plasma endothelin and soluble interleukin-2 receptor in patients with systemic lupus erythematosus., Chin. J. Integr. Med. 11, 65–68 (2005). https://doi.org/10.1007/BF02835754

Cheng Shi-ping, Liu Jia-lin, Yuan Jing. Study of the effect of leeching on plasma endothelin and soluble interleukin-2 receptor in patients with systemic lupus erythematosus. [J]. Chinese Journal of Integrative Medicine 11(1):65-68(2005)
Shi-ping, C., Jia-lin, L. & Jing, Y. Study of the effect of leeching on plasma endothelin and soluble interleukin-2 receptor in patients with systemic lupus erythematosus., Chin. J. Integr. Med. 11, 65–68 (2005). https://doi.org/10.1007/BF02835754 DOI：

Cheng Shi-ping, Liu Jia-lin, Yuan Jing. Study of the effect of leeching on plasma endothelin and soluble interleukin-2 receptor in patients with systemic lupus erythematosus. [J]. Chinese Journal of Integrative Medicine 11(1):65-68(2005) DOI： 10.1007/BF02835754.

摘要

Objective: to explore the mechanism of leeching in treating systemic lupus erythematosus (SLE).Methods: Forty-four patients with SLE were randomly divided into conventional corticosteroid treated group (control group

n = 20) and conventional treatment group with leeching intervention added (leeching group

n = 24). Before and after treatment the concentration of plasma endothelin (ET) and soluble interleukin-2 receptor (sIL-2R) were determined.Results: Before treatment the level of plasma ET and sIL-2R in the SLE patients were all higher than those in the normal healthy group

(P<0.01). But after treatment the level of these in both groups were significantly improved than those of before treatment (P<0.05)

and comparison between these two treated groups showed that the difference between them was significant (P<0.05).Conclusion: Leeching added to conventional treatment of SLE could be more effective in improving the level of plasma ET and sIL-2R

and ameliorating the impairment of renal tissues.

Abstract

n = 20) and conventional treatment group with leeching intervention added (leeching group

(P<0.01). But after treatment the level of these in both groups were significantly improved than those of before treatment (P<0.05)

and ameliorating the impairment of renal tissues.

关键词

systemic lupus erythematosusendothelinsoluble interleukin-2 receptorleech

Keywords

systemic lupus erythematosusendothelinsoluble interleukin-2 receptorleech

references

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Burns Institute, First Hospital Affiliated to the Chinese PLA General Hospital

Chinese Center for Disease Control and Prevention

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Departement of Rheumatology, Immunology and Nephropathy, Zhejiang Provincial Hospital of Integrated Chinese and Western Medicine, Hanghzhou

Department of Rheumatology and Immunology, Hospital of Integrative Chinese and Western Medicine

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