Feng, G., Xiu-fen, H. Analysis of the therapeutic effect of sodium copper chlorophyllin tablet in treating 60 cases of leukopenia., Chin. J. Integr. Med. 11, 279–282 (2005). https://doi.org/10.1007/BF02835789
Gao Feng, Hu Xiu-fen. Analysis of the therapeutic effect of sodium copper chlorophyllin tablet in treating 60 cases of leukopenia. [J]. Chinese Journal of Integrative Medicine 11(4):279-282(2005)
Feng, G., Xiu-fen, H. Analysis of the therapeutic effect of sodium copper chlorophyllin tablet in treating 60 cases of leukopenia., Chin. J. Integr. Med. 11, 279–282 (2005). https://doi.org/10.1007/BF02835789DOI:
Gao Feng, Hu Xiu-fen. Analysis of the therapeutic effect of sodium copper chlorophyllin tablet in treating 60 cases of leukopenia. [J]. Chinese Journal of Integrative Medicine 11(4):279-282(2005) DOI: 10.1007/BF02835789.
Analysis of the therapeutic effect of sodium copper chlorophyllin tablet in treating 60 cases of leukopenia
摘要
Objective: To evaluate the efficacy and safety of sodium copper chlorophyllin (trademarked as “Yebaike Tablet which is abbreviated as YBK in treating leukopenia.Methods: One hundred and five patients with leukopenia caused by various factors were randomized into 3 groups. The 60 patients in the YBK group took orally YBK Tablets at the dose of 40 mg
three times per day
the 30 patients in the leucogen group were treated with Leucogen Tablets at the dose of 20 mg
three times per day
and the 15 patients in the placebo group were administered with vitamin C tablets 100 mg
three times per day. All the subjects were treated for 1 month. The change of peripheral leucocytes count after treatment and adverse drug reaction that occurred in patients were studied.Results: In the 60 patients treated with YBK
the treatment proved to be markedly effective in 34 cases
effective in 17 and ineffective in 9
the total effective rate being 85%
which was significantly higher than that in the placebo group (26.7%
P<0.01) and similar to that in the leucogen group (83. 3%
P>0.05). No adverse reaction was found in the treatment course.Conclusion: YBK can be used in the treatment of leukopenia caused by various factors
satisfactory in efficacy and safe in use.
Abstract
Objective: To evaluate the efficacy and safety of sodium copper chlorophyllin (trademarked as “Yebaike Tablet which is abbreviated as YBK in treating leukopenia.Methods: One hundred and five patients with leukopenia caused by various factors were randomized into 3 groups. The 60 patients in the YBK group took orally YBK Tablets at the dose of 40 mg
three times per day
the 30 patients in the leucogen group were treated with Leucogen Tablets at the dose of 20 mg
three times per day
and the 15 patients in the placebo group were administered with vitamin C tablets 100 mg
three times per day. All the subjects were treated for 1 month. The change of peripheral leucocytes count after treatment and adverse drug reaction that occurred in patients were studied.Results: In the 60 patients treated with YBK
the treatment proved to be markedly effective in 34 cases
effective in 17 and ineffective in 9
the total effective rate being 85%
which was significantly higher than that in the placebo group (26.7%
P<0.01) and similar to that in the leucogen group (83. 3%
P>0.05). No adverse reaction was found in the treatment course.Conclusion: YBK can be used in the treatment of leukopenia caused by various factors
satisfactory in efficacy and safe in use.
关键词
leukopeniasodium copper chlorophyllin
Keywords
leukopeniasodium copper chlorophyllin
references
Hao JP, Yan WS. Effect of sodium copper chlorophyllin tablet in treating leukopenia induced by anti-thyroid drugs. J Pract Med 2004; 20(2): 205.
He XL. Clinical observation of sodium copper chlorophyllin tablet in treating 54 cases of neutropenia in children. J Chin Phys 2004; 6(2): 272.
Fang GQ, Zhu AP, Xu Y. Effect of sodium copper chlorophyllin in treating leukopenia. Anhui Med J 2001;22(5): 58–59.
Zhang ZN, editor. Criteria for the diagnosis and efficacy evaluation of hematologic diseases. 2nd ed. Beijing: Science Press, 1998: 174–176.
Luo SK, Hong WD, editors. Hematopathy and diseases of hematopoietic system. Beijing: Scientific and Technologic Literature Publishing House, 1999: 66–68.
Wang ZY, Gao ZT, Liu SQ. New progress on application of sodium copper chlorophyllin and its derivative in medicine and pharmacy. Chongqing J Chin Tradit Herb Drugs 1999; 40(10): 167–172.
Su GL, Shi L. Pharmadynamic study and clinical observation of quickly released gastric drug sodium copper chlorophyllin tablets. Lishizhen Med Meteria Medica Res 2001: 12(7): 623–624.
Zhu LQ, Shen NC. Experimental study of sodium copper chlorophyllin in protecting liver from acute and chronic injury. Chin J Pharm 1990; 21(10): 442–445.