Extracts of monascusus purpureus beyond statins —Profile of efficacy and safety of the use of extracts of monascus purpureus

Bianchi Antonio

doi:10.1007/BF02835797

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Extracts of monascusus purpureus beyond statins —Profile of efficacy and safety of the use of extracts of monascus purpureus

Updated：2021-08-27

- Extracts of monascusus purpureus beyond statins —Profile of efficacy and safety of the use of extracts of monascus purpureus
- Chinese Journal of Integrative Medicine Vol. 11, Issue 4, Pages: 309-313(2005)
- Affiliations：
  
  .NA.., Crocetta del Montello (TV),CO,RE,Italy
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- DOI：10.1007/BF02835797
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- Published：2005，
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Antonio, B. Extracts of monascusus purpureus beyond statins —Profile of efficacy and safety of the use of extracts of monascus purpureus., Chin. J. Integr. Med. 11, 309–313 (2005). https://doi.org/10.1007/BF02835797

Bianchi Antonio. Extracts of monascusus purpureus beyond statins —Profile of efficacy and safety of the use of extracts of monascus purpureus. [J]. Chinese Journal of Integrative Medicine 11(4):309-313(2005)
Antonio, B. Extracts of monascusus purpureus beyond statins —Profile of efficacy and safety of the use of extracts of monascus purpureus., Chin. J. Integr. Med. 11, 309–313 (2005). https://doi.org/10.1007/BF02835797 DOI：

Bianchi Antonio. Extracts of monascusus purpureus beyond statins —Profile of efficacy and safety of the use of extracts of monascus purpureus. [J]. Chinese Journal of Integrative Medicine 11(4):309-313(2005) DOI： 10.1007/BF02835797.

摘要

Extracts of Monascus purpureus have always been considered a natural source of lovastatin

the precursor of the world’s largest selling class of drugs. In actual fact

the fungus contains many other substances (flavonoids

polyunsaturated fats

pyrrolinic compounds etc.) with a wide variety of other actions. The most recent studies have shown that it has an action on the glycemic metabolism

and on the mechanisms of adipogenesis

also an effects on the endothelium and on postprandial vasodilation. These effects are more extensive and complex than those of statins alone. And new strains of Monascus purpureus have recently been patented where the presence of statins is only one of the therapeutic components of the fungus. In particular

the increase in secondary components

such as flavonoids

which coincides with a more complex therapeutic action

probably making the new extracts of Monascus purpureus

the ideal candidate for the treatment of the metabolic syndrome.

Abstract

Extracts of Monascus purpureus have always been considered a natural source of lovastatin

the precursor of the world’s largest selling class of drugs. In actual fact

the fungus contains many other substances (flavonoids

polyunsaturated fats

pyrrolinic compounds etc.) with a wide variety of other actions. The most recent studies have shown that it has an action on the glycemic metabolism

and on the mechanisms of adipogenesis

the increase in secondary components

such as flavonoids

which coincides with a more complex therapeutic action

probably making the new extracts of Monascus purpureus

the ideal candidate for the treatment of the metabolic syndrome.

关键词

Monascus purpureuscholesterolmetabolic syndrome

Keywords

Monascus purpureuscholesterolmetabolic syndrome

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Integration of Chinese and Western Medicine Laboratory of the First Hospital, Graduate School of Integration of Chinese and Western Medicine, Beijing Medical University

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University

School of Traditional Chinese Materia Medicine, Shenyang Pharmaceutical University

Fujian Institute of Traditional Chinese Medicine

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