Objective:In comparison with chemotherapy

to evaluate therapeutic effects on advanced pancreatic cancer treated by integrative Chinese and western medicine (ICWM) therapies.Methods: Based on the retrospective study of 56 patients with advanced pancreatic cancer

life table was applied to the analysis of patients’ survival rate and χ2 test to the comparison of therapeutic response between ICWM and chemotherapy groups.Results: The results showed that 1-year survival rate in the ICWM group was 55. 37%±3.24%; 2-year survival rate 34. 61%±16. 31%; 3-year survival rate 25. 96%±24. 64%; 5-year survival rate 2596%±24.64%; and median survival period 16.3 months. However 1-year survival rate in the chemotherapy group was 21. 95%±27. 54%; 2-year survival rate 7. 31%±27. 54%; 3-year survival rate 0%; and median survival period 7. 5 months. The therapeutic effects between two groups were significantly different (P=0. 004). Further analysis suggested that the reduction of cancer mass in the ICWM group was more than that in chemotherapy group (P=0.049) and the improvement of advanced pancreatic cancer related-symptoms better than that of chemotherapy group (P = 0. 002).Conclusion: The ICWM comprehensive therapy is of important value in the treatment of advanced pancreatic cancer.