Study of interference treatment by Xuesaitong soft capsule on patients of nephrosis syndrome with Qi deficiency and blood stasis during dose reducing stage of corticosteroid

Lu Yong; Wang Yi-ping; Zhang Li

doi:10.1007/BF02836408

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Study of interference treatment by Xuesaitong soft capsule on patients of nephrosis syndrome with Qi deficiency and blood stasis during dose reducing stage of corticosteroid

Updated：2021-08-27

- Study of interference treatment by Xuesaitong soft capsule on patients of nephrosis syndrome with Qi deficiency and blood stasis during dose reducing stage of corticosteroid
- Chinese Journal of Integrative Medicine Vol. 10, Issue 3, Pages: 203-207(2004)
- Affiliations：
  
  Nephropathy Department, The First Affiliated Hospital to Anhui College of TCM,Hefei,China
- Author bio：
- Funds：
- DOI：10.1007/BF02836408
  CLC：
- Published：2004，
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Yong, L., Yi-ping, W. & Li, Z. Study of interference treatment by Xuesaitong soft capsule on patients of nephrosis syndrome with Qi deficiency and blood stasis during dose reducing stage of corticosteroid., Chin. J. Integr. Med. 10, 203–207 (2004). https://doi.org/10.1007/BF02836408

Lu Yong, Wang Yi-ping, Zhang Li. Study of interference treatment by Xuesaitong soft capsule on patients of nephrosis syndrome with Qi deficiency and blood stasis during dose reducing stage of corticosteroid. [J]. Chinese Journal of Integrative Medicine 10(3):203-207(2004)
Yong, L., Yi-ping, W. & Li, Z. Study of interference treatment by Xuesaitong soft capsule on patients of nephrosis syndrome with Qi deficiency and blood stasis during dose reducing stage of corticosteroid., Chin. J. Integr. Med. 10, 203–207 (2004). https://doi.org/10.1007/BF02836408 DOI：

Lu Yong, Wang Yi-ping, Zhang Li. Study of interference treatment by Xuesaitong soft capsule on patients of nephrosis syndrome with Qi deficiency and blood stasis during dose reducing stage of corticosteroid. [J]. Chinese Journal of Integrative Medicine 10(3):203-207(2004) DOI： 10.1007/BF02836408.

摘要

Objective: To observe the effect of Xuesaitong (XST) soft capsule in interference treatment on patients of nephrosis syndrome (NS) during corticosteroid (CS) dose reducing stage.Methods: Seventy-one NS patients applying prednisone and initiating dose reducing stage were randomized into trial group and control group. On the basis of conventional prednisone dose reduction of both groups

the trial group was given additionally XST

and the treatment course ended with the reduction to maintenance dose. In the course of observation

those who did not comply with the criteria of observation were excluded. Before and after the dose reduction

TCM syndrome scoring

24 hrs urinary protein amount

blood β2-microglobulin (β2-MG)

urinary β2-MG

blood fibrinogen (Fbg)

plasma prothrombin time (PT)

blood lipid

etc. were observed.Results: The trial group of XST could obviously lower their urinary protein amount and blood lipid level (P<0.05 orP<0.01)

markedly improve the blood coagulation parameters (P<0.01)

improve the TCM syndrome and CS induced adverse reaction (P<0.05 orP<0.01)

also obviously reduced the recurrence rate of NS (P<0.05).Conclusion: XST could obviously improve the clinical symptoms and renal impairment parameters in NS patients during CS dose reduction stage

improve the CS induced adverse reaction and prevent the recurrence of NS.

Abstract

the trial group was given additionally XST

and the treatment course ended with the reduction to maintenance dose. In the course of observation

those who did not comply with the criteria of observation were excluded. Before and after the dose reduction

TCM syndrome scoring

24 hrs urinary protein amount

blood β2-microglobulin (β2-MG)

urinary β2-MG

blood fibrinogen (Fbg)

plasma prothrombin time (PT)

blood lipid

etc. were observed.Results: The trial group of XST could obviously lower their urinary protein amount and blood lipid level (P<0.05 orP<0.01)

markedly improve the blood coagulation parameters (P<0.01)

improve the TCM syndrome and CS induced adverse reaction (P<0.05 orP<0.01)

also obviously reduced the recurrence rate of NS (P<0.05).Conclusion: XST could obviously improve the clinical symptoms and renal impairment parameters in NS patients during CS dose reduction stage

improve the CS induced adverse reaction and prevent the recurrence of NS.

关键词

nephrosis syndromecorticosteroidQi deficiency and blood stasisXuesaitong soft capsule

Keywords

nephrosis syndromecorticosteroidQi deficiency and blood stasisXuesaitong soft capsule

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