Objective: To explore the relationship between Shen deficiency and blood stasis.Methods: Using consecutive intramuscular injection of hydrocortisone to build Shen-yang deficiency model rats

and detect their hemorheological and biochemical parameters.Results: Comparison between the model group and control group showed that the in vitro thrombus significantly lengthened in the model group (P<0.05)

the dry weight increased (P<0.01)

hematocrit and whole blood viscosity under high sheared change lowered (P<0.05)

blood glucose elevated (P<0.01)

and RBC infiltration index

aggregation index increased (P close to 0.05).Conclusion: Under the condition of Shen-yang deficiency

although blood does not show such properties of blood stasis as being “viscous

concentrated

coagulated and aggregated”

partial change of hemorheology occurs

and it is liable to form thrombus

which proves that the Shen deficiency status is accompanied with the tendency of blood stasis.