The state of insulin resistance in patients with nonalcoholic fatty liver and the intervention with Gankangyin

Deng Yin-quan; Fan Xiao-fen; Li Jian-ping

doi:10.1007/BF02836467

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The state of insulin resistance in patients with nonalcoholic fatty liver and the intervention with Gankangyin

Updated：2021-08-27

- The state of insulin resistance in patients with nonalcoholic fatty liver and the intervention with Gankangyin
- Chinese Journal of Integrative Medicine Vol. 11, Issue 2, Pages: 117-122(2005)
- Affiliations：
  
  First Affiliated Hospital, Medical College of Zhejiang University,Hangzhou
- Author bio：
- Funds：
- DOI：10.1007/BF02836467
  CLC：
- Published：2005，
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Yin-quan, D., Xiao-fen, F. & Jian-ping, L. The state of insulin resistance in patients with nonalcoholic fatty liver and the intervention with Gankangyin., Chin. J. Integr. Med. 11, 117–122 (2005). https://doi.org/10.1007/BF02836467

Deng Yin-quan, Fan Xiao-fen, Li Jian-ping. The state of insulin resistance in patients with nonalcoholic fatty liver and the intervention with Gankangyin. [J]. Chinese Journal of Integrative Medicine 11(2):117-122(2005)
Yin-quan, D., Xiao-fen, F. & Jian-ping, L. The state of insulin resistance in patients with nonalcoholic fatty liver and the intervention with Gankangyin., Chin. J. Integr. Med. 11, 117–122 (2005). https://doi.org/10.1007/BF02836467 DOI：

Deng Yin-quan, Fan Xiao-fen, Li Jian-ping. The state of insulin resistance in patients with nonalcoholic fatty liver and the intervention with Gankangyin. [J]. Chinese Journal of Integrative Medicine 11(2):117-122(2005) DOI： 10.1007/BF02836467.

摘要

Objective: To explore the correlation of nonalcoholic fatty liver (NAFL) with insulin resistance and the intervention of it by Gankangyin(GKY).Methods: Ninety-six patients with NAFL were randomly assigned into the treated group and the control group. They were treated with GKY and Silymarin for 3 months respectively. Oral glucose tolerance test (OGTT) and insulin release test (IRT) were conducted and insulin sensitivity indexes were determined before and after treatment. And 32 healthy nonalcoholic persons were enrolled and used as the healthy control group.Results: Before treatment

the levels of blood glucose and insulin at different time points in OGTT test

and the insulin resistance index (IRI) were significantly higher (P<0.05 orP<0.01) while insulin sensitivity index (ISI) and insulin active index (IAI) were lower (P<0.05 orP<0.01) in the NAFL patients than those in the healthy persons. After treatment

the above-mentioned raised criteria were significantly lowered (P<0.05

P<0.01) and the lowered criteria were significantly increased (P<0.01) in the treated group

while in the control group all the criteria were insignificantly changed (P>0. 05).Conclusion: Evident insulin resistance exists in NAFL patients. GKY could’increase the insulin sensitivity

thus improving the state of insulin resistance in NAFL patients.

Abstract

the levels of blood glucose and insulin at different time points in OGTT test

the above-mentioned raised criteria were significantly lowered (P<0.05

P<0.01) and the lowered criteria were significantly increased (P<0.01) in the treated group

while in the control group all the criteria were insignificantly changed (P>0. 05).Conclusion: Evident insulin resistance exists in NAFL patients. GKY could’increase the insulin sensitivity

thus improving the state of insulin resistance in NAFL patients.

关键词

nonalcoholic fatty liverinsulin resistanceGankangyin

Keywords

nonalcoholic fatty liverinsulin resistanceGankangyin

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