Effect of Xuesaitong soft capsule on hemorrheology and in auxiliarily treating patients with acute cerebral infarction

Zhong Shang-qian; Sun Li-jing; Yan Yu-zhen; Sun Yan-qin; Zhong Yin-yuan

doi:10.1007/BF02836469

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Effect of Xuesaitong soft capsule on hemorrheology and in auxiliarily treating patients with acute cerebral infarction

Updated：2021-08-27

- Effect of Xuesaitong soft capsule on hemorrheology and in auxiliarily treating patients with acute cerebral infarction
- Chinese Journal of Integrative Medicine Vol. 11, Issue 2, Pages: 128-131(2005)
- Affiliations：
  
  The Second People’s Hospital of Liaocheng,Shandong
- Author bio：
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- DOI：10.1007/BF02836469
  CLC：
- Published：2005，
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Shang-qian, Z., Li-jing, S., Yu-zhen, Y. et al. Effect of Xuesaitong soft capsule on hemorrheology and in auxiliarily treating patients with acute cerebral infarction., Chin. J. Integr. Med. 11, 128–131 (2005). https://doi.org/10.1007/BF02836469

Zhong Shang-qian, Sun Li-jing, Yan Yu-zhen, et al. Effect of Xuesaitong soft capsule on hemorrheology and in auxiliarily treating patients with acute cerebral infarction. [J]. Chinese Journal of Integrative Medicine 11(2):128-131(2005)
Shang-qian, Z., Li-jing, S., Yu-zhen, Y. et al. Effect of Xuesaitong soft capsule on hemorrheology and in auxiliarily treating patients with acute cerebral infarction., Chin. J. Integr. Med. 11, 128–131 (2005). https://doi.org/10.1007/BF02836469 DOI：

Zhong Shang-qian, Sun Li-jing, Yan Yu-zhen, et al. Effect of Xuesaitong soft capsule on hemorrheology and in auxiliarily treating patients with acute cerebral infarction. [J]. Chinese Journal of Integrative Medicine 11(2):128-131(2005) DOI： 10.1007/BF02836469.

摘要

Objective: To observe the therapeutic effect of Xuesaitong soft capsule (XST and its effect on platelet counts

coagulation factor 1 (CF1) as well as hemorrheologic indexes in treating patients with acute cerebral infarction (ACI).Methods: Two hundred and four patients with ACI were assigned into two groups

the control group (n = 96) and the treated group (n = 108). They were all treated with conventional Western medicines

including mannitol

troxerutin

citicoline

piracetam and aspirin

while to the treated group

XST was given additionally through oral intake

twice a day

2 capsules each time for 8 successive weeks. The clinical efficacy was evaluated according to the nerve function deficits scoring and the changes of platelet count. CF1 and hemorrheological indexes were measured before and after treatment.Results: The total effective rate was 87.0% in the treated group

and 87. 5% in the control group

respectively

showing insignificant difference between them. But the markedly effective rate in the treated group (66.7%) was significantly higher than that in the control group (27.1%

P<0. 01). The count of platelet was not changed significantly in both groups after treatment

while CF1 in them evidently lowered at the end of the 4th and 8th weeks of treatment

but showed insignificant difference between the two groups. The hematocrit

whole blood viscosity and plasma viscosity in both groups were all improved significantly after treatment

but also showed insignificant difference in comparison of the two groups.Conclusion: XST has good efficacy in auxiliary treatment of patients with ACI

though its mechanism remains to be further explored.

Abstract

Objective: To observe the therapeutic effect of Xuesaitong soft capsule (XST and its effect on platelet counts

coagulation factor 1 (CF1) as well as hemorrheologic indexes in treating patients with acute cerebral infarction (ACI).Methods: Two hundred and four patients with ACI were assigned into two groups

the control group (n = 96) and the treated group (n = 108). They were all treated with conventional Western medicines

including mannitol

troxerutin

citicoline

piracetam and aspirin

while to the treated group

XST was given additionally through oral intake

twice a day

and 87. 5% in the control group

respectively

showing insignificant difference between them. But the markedly effective rate in the treated group (66.7%) was significantly higher than that in the control group (27.1%

P<0. 01). The count of platelet was not changed significantly in both groups after treatment

while CF1 in them evidently lowered at the end of the 4th and 8th weeks of treatment

but showed insignificant difference between the two groups. The hematocrit

whole blood viscosity and plasma viscosity in both groups were all improved significantly after treatment

but also showed insignificant difference in comparison of the two groups.Conclusion: XST has good efficacy in auxiliary treatment of patients with ACI

though its mechanism remains to be further explored.

关键词

Xuesaitong soft capsulenerve function deficits scoringhemorrheologic indexesacute cerebral infarction

Keywords

Xuesaitong soft capsulenerve function deficits scoringhemorrheologic indexesacute cerebral infarction

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The First Hospital Affiliated to Medical College of Zhejiang University

Neurology Department, Hospital Affiliated to Nanjing University of TCM

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The Second Affiliated Hospital of Nanjing Medical University

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