Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property

Shi Hong-zhi; Gao Nan-nan; Li Yong-zhi; Yu Jing-guang; Fan Quan-chun; Bai Gui-e; Xin Bing-mu

doi:10.1007/BF02836470

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Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property

Updated：2021-08-27

- Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property
- Chinese Journal of Integrative Medicine Vol. 11, Issue 2, Pages: 132-135(2005)
- Affiliations：
  
  1. Institute of Space Medico-Engineering,Beijing
  2. Institute of Medicinal Plant Development, China Academy of Medical Science,China
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China (No. 39770899)
- DOI：10.1007/BF02836470
  CLC：
- Published：2005，
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Hong-zhi, S., Nan-nan, G., Yong-zhi, L. et al. Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property., Chin. J. Integr. Med. 11, 132–135 (2005). https://doi.org/10.1007/BF02836470

Shi Hong-zhi, Gao Nan-nan, Li Yong-zhi, et al. Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property. [J]. Chinese Journal of Integrative Medicine 11(2):132-135(2005)
Hong-zhi, S., Nan-nan, G., Yong-zhi, L. et al. Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property., Chin. J. Integr. Med. 11, 132–135 (2005). https://doi.org/10.1007/BF02836470 DOI：

Shi Hong-zhi, Gao Nan-nan, Li Yong-zhi, et al. Effects of L. F04, the active fraction ofLycopus lucidus, on erythrocytes rheological property. [J]. Chinese Journal of Integrative Medicine 11(2):132-135(2005) DOI： 10.1007/BF02836470.

摘要

Objective: To study the effects of L. F04

the active fraction ofLycopus lucidus

on erythrocytes rheological property so as to investigate its mechanism in promoting blood circulation and removing blood stasis.Method: The effects of L. F04 (used for treatment for 10 days in different dosages) on deformability

aggregation and membrane liquidity of erythrocytes (MLE) as well as whole blood apparent viscosity (ηb) were examined on the basis of rat model of blood-stasis syndrome induced by venous injection of high molecular weight dextran.Result: As compared with the normal control group

the model group’s RBC deformability and MLE were lower

and the aggregation of erythrocytes and ηb were higher. Compared with the model group

both L. F04 0. 612g/kg and 0.306g/kg showed significant effect in improving deformability and inhibiting aggregation of red blood cells (RBC) and reducing blood viscosity. The trend of improving MLE was also shown.Conclusion: L. F04 could significantly improve the abnormal rheological property of erythrocytes.

Abstract

Objective: To study the effects of L. F04

the active fraction ofLycopus lucidus

the model group’s RBC deformability and MLE were lower

and the aggregation of erythrocytes and ηb were higher. Compared with the model group

关键词

Lycopus lucidusblood-stasisdeformability of erythrocytesaggregation of erythrocytesmembrane liquidity of erythrocyteswhole blood apparent viscosityL. F04

Keywords

Lycopus lucidusblood-stasisdeformability of erythrocytesaggregation of erythrocytesmembrane liquidity of erythrocyteswhole blood apparent viscosityL. F04

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