Clinical observation of Gingko biloba extract injection in treating early diabetic nephropathy

Lu Jie; He Hai

doi:10.1007/BF02836510

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Clinical observation of Gingko biloba extract injection in treating early diabetic nephropathy

Updated：2021-08-27

- Clinical observation of Gingko biloba extract injection in treating early diabetic nephropathy
- Chinese Journal of Integrative Medicine Vol. 11, Issue 3, Pages: 226-228(2005)
- Affiliations：
  
  1. Department of Nephrology, Affiliated Hospital of Guangdong Medical College,Zhanjiang
  2. The First Central Hospital of Tianjin,China
- Author bio：
- Funds：
- DOI：10.1007/BF02836510
  CLC：
- Published：2005，
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Jie, L., Hai, H. Clinical observation of Gingko biloba extract injection in treating early diabetic nephropathy., Chin. J. Integr. Med. 11, 226–228 (2005). https://doi.org/10.1007/BF02836510

Lu Jie, He Hai. Clinical observation of Gingko biloba extract injection in treating early diabetic nephropathy. [J]. Chinese Journal of Integrative Medicine 11(3):226-228(2005)
Jie, L., Hai, H. Clinical observation of Gingko biloba extract injection in treating early diabetic nephropathy., Chin. J. Integr. Med. 11, 226–228 (2005). https://doi.org/10.1007/BF02836510 DOI：

Lu Jie, He Hai. Clinical observation of Gingko biloba extract injection in treating early diabetic nephropathy. [J]. Chinese Journal of Integrative Medicine 11(3):226-228(2005) DOI： 10.1007/BF02836510.

摘要

Objective: To observe the effect of Ginkgo biloba extract injection (GB) in treating early diabetic nephropathy (DN).Methods: Sixty DN patients were divided into two groups

the treated group were treated by GB and Western medicine

and the control group were given Western medicine alone. The study lasted for 4 weeks. Fasting plasma glucose (FPG)

blood pressure

24 h urinary albumin excretion (UAE)

endogenous creatinine clearance rate (Ccr)

blood lipids and hemorheology indices were examined before and after the study. Results: Compared with the control group

UAE were significantly decreased (P<0. 01); Ccr

blood lipids and hemorheology indices were all improved after treatment in the treated group (P< 0.05 orP<0.01). But in FPG and blood pressure there was no significant change between the treated group and the control group (P>0.05).Conclusion: GB is effective in treating early DN through decreasing urinary albumin excretion rate

regulating blood lipids

improving renal function and hemorheology.

Abstract

Objective: To observe the effect of Ginkgo biloba extract injection (GB) in treating early diabetic nephropathy (DN).Methods: Sixty DN patients were divided into two groups

the treated group were treated by GB and Western medicine

and the control group were given Western medicine alone. The study lasted for 4 weeks. Fasting plasma glucose (FPG)

blood pressure

24 h urinary albumin excretion (UAE)

endogenous creatinine clearance rate (Ccr)

blood lipids and hemorheology indices were examined before and after the study. Results: Compared with the control group

UAE were significantly decreased (P<0. 01); Ccr

regulating blood lipids

improving renal function and hemorheology.

关键词

Ginkgo biloba extract injectiondiabetic nephropathyClinical Observation

Keywords

Ginkgo biloba extract injectiondiabetic nephropathyClinical Observation

references

Pan CY, Jin WS. Strengthening the screening of trace albuminuria, to elevate the level of preventing and treating diabetic nephropathy. Chin J Intern Med 2004; 43 (3): 161–162.

Wolf G. Cell cycle regulation in diabetic nephropathy. Kidney Int 2000; 58(suppl 77): 59–68.

Kang H, Huang M. Ginkgo biloba leaf extract pharmacologic study survey. J Pharm Practice 2002; 20 (6): 334–338.

Liao P, Wang SQ, Liao XS, et al. Experimental study of Ginkgo biloba leaf extract on DM rats’ nephroprotection. Chin Pharmacy 2000; 11 (3): 114–115.

Tang JH, Xu QR, Liu TL, et al. Experimental study on Ginkgo biloba leaf preventing and treating glomerulosclerosis and tubulo-interstitial injury. Chin J Nephrol 1998; 14 (3): 174–176.

Zhao J, Wang JJ, Liu YF. Effect of Ginkgo biloba preparation on geriatric cerebral infarction accompanied DM patients hemorheology. Chin Microcirc 2002; 6 (4): 218–219.

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Department of Pharmacy, College of Chemical and Chemistry Engineering, Hu’nan University

Department of Basic Guiyang College of Traditional Chinese Medicine

Department of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology

Zhejiang University of Traditional Chinese Medicine

Dongzhimen Hospital, Beijing University of Chinese Medicine

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