Effects of Quyu Xiaoban Capsule on vascular endothelial function in patients with atherosclerosis

Liu Yun-fang; Zhao Yu-xia; Yu Hui-ming

doi:10.1007/BF02836516

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Effects of Quyu Xiaoban Capsule on vascular endothelial function in patients with atherosclerosis

Updated：2021-08-27

- Effects of Quyu Xiaoban Capsule on vascular endothelial function in patients with atherosclerosis
- Chinese Journal of Integrative Medicine Vol. 12, Issue 3, Pages: 171-174(2006)
- Affiliations：
  
  1. Department of Diagnosis, School of Medicine, Shandong University,Jinan
  2. Department of Traditional Chinese Medicine, Qilu Hospital, Shandong University,China
- Author bio：
- Funds：
  
  Supported by the 9th 5-year Key Project of Shandong Provincial Ministry of Health (No. 9711)
- DOI：10.1007/BF02836516
  CLC：
- Published：2006，
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Yun-fang, L., Yu-xia, Z. & Hui-ming, Y. Effects of Quyu Xiaoban Capsule on vascular endothelial function in patients with atherosclerosis., Chin. J. Integr. Med. 12, 171–174 (2006). https://doi.org/10.1007/BF02836516

Liu Yun-fang, Zhao Yu-xia, Yu Hui-ming. Effects of Quyu Xiaoban Capsule on vascular endothelial function in patients with atherosclerosis. [J]. Chinese Journal of Integrative Medicine 12(3):171-174(2006)
Yun-fang, L., Yu-xia, Z. & Hui-ming, Y. Effects of Quyu Xiaoban Capsule on vascular endothelial function in patients with atherosclerosis., Chin. J. Integr. Med. 12, 171–174 (2006). https://doi.org/10.1007/BF02836516 DOI：

Liu Yun-fang, Zhao Yu-xia, Yu Hui-ming. Effects of Quyu Xiaoban Capsule on vascular endothelial function in patients with atherosclerosis. [J]. Chinese Journal of Integrative Medicine 12(3):171-174(2006) DOI： 10.1007/BF02836516.

摘要

Objective: To evaluate the therapeutic effects of Quyu Xiaoban Capsule

(QYXBC) on endothelial dependent vascular relaxation (EDVR) function in patients with atherosclerosis (AS) with ultrasonic technique.Methods: Tested were the endothelial function and blood lipids of 42 patients with AS in the treated group and 30 healthy volunteers in the control group. And re-examination of these parameters was carried out on the AS patients after they had been treated with QYXBC for 10 months.Results: Before treatment

the reactive hyperemia induced changes in artery diameter in the treated group was significantly lower than that in the control group (P < 0.01)

while insignificant difference was found between the two groups in response to nitroglycerin. In the treated group after treatment

with D%-R improved significantly (P < 0.01)

total cholesterol (TC)

triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) decreased by 16.3%

5.6%

10.2% respectively and high-density lipoprotein cholesterol (HDL-C) increased by 7.5%. EDVR was correlated negatively with the serum TC

LDL-C concentrations and the baseline brachial diameter (D0 (r = -0.41

-0.66

-0.59

respectively

allP < 0.01)

but correlated positively with HDL-C (r = 0.62

P < 0.05). The ameliorative extent of EDVR was correlated positively to the decreased magnitude of TC and LDL-C concentrations (r = 0.67

0.59

bothP < 0.01).Conclusion: QYXBC can lower the level of blood lipids and improve significantly EDVR function.

Abstract

Objective: To evaluate the therapeutic effects of Quyu Xiaoban Capsule

the reactive hyperemia induced changes in artery diameter in the treated group was significantly lower than that in the control group (P < 0.01)

while insignificant difference was found between the two groups in response to nitroglycerin. In the treated group after treatment

with D%-R improved significantly (P < 0.01)

total cholesterol (TC)

triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) decreased by 16.3%

5.6%

10.2% respectively and high-density lipoprotein cholesterol (HDL-C) increased by 7.5%. EDVR was correlated negatively with the serum TC

LDL-C concentrations and the baseline brachial diameter (D0 (r = -0.41

-0.66

-0.59

respectively

allP < 0.01)

but correlated positively with HDL-C (r = 0.62

P < 0.05). The ameliorative extent of EDVR was correlated positively to the decreased magnitude of TC and LDL-C concentrations (r = 0.67

0.59

bothP < 0.01).Conclusion: QYXBC can lower the level of blood lipids and improve significantly EDVR function.

关键词

Quyu Xiaoban Capsuleatherosclerosisendothelial function

Keywords

Quyu Xiaoban Capsuleatherosclerosisendothelial function

references

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Department of Traditional Chinese Medicine, Shanghai No. 6 People’s Hospital, Affiliated to Shanghai Jiaotong University

Lab, First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou

Department of Cardiology, First Affiliated Hospital of Zhejiang Chinese Medical University

Zhujiang Hospital, Southern Medical University

Integrative Hospital, College of Chinese Medicine, Southern Medical University

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