Objective: To explore the clinical efficacy of Xuefu Zhuyu

XFZY) oral liquid combined with western medicine (WM) in reversing left ventricle remodeling (LVR) after acute myocardial infarction (AMI) in patients and its therapeutic mechanism.Methods: Sixty patients conforming to criteria were divided into the treated group and WM control group with randomly stratified method. Thirty cases were assigned to each group

they were given XFZY + WM + general treatment and WM + general treatment respectively. Color Doppler ultrasonography was used to study the changes of LVR before and after treatment. Results: In both groups

before and after treatment theP value of such parameters as the changes of their left diastolic volume (LDV)

left systolic volume (LSV)

left ventricle ejection fraction (EF) was <0.05

suggesting that the difference of various parameters was significantly different; but when compared with the results of the 12th week after medications

the change of LDV

LSV

EF showed that the LDV

LSV of the treated group were lower than that of the control group

the EF of the treated group was higher than that of the control group

and theP value of various groups was all <0.05

suggesting that the different data of various groups showed significant difference.Conclusion: Conventional WM treatment and XFZY combined with WM could both

in treating AMI

effectively reverse the patients’ LVR; yet the use of integrative Chinese and western medicine on reversing patient’s LVR showed even better results than that of simple WM treatment.