Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction

Zhang Jin-guo; Gao Dong-sheng; Yang Na; Liu Li-xin; He Hua; Dong Hai-xin; Liu Xue-ling; Chen Ting; Wang Xue-zhong; Liu Ya-jie

doi:10.1007/BF02838559

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Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction

Updated：2021-08-27

- Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction
- Chinese Journal of Integrative Medicine Vol. 9, Issue 2, Pages: 104-107(2003)
- Affiliations：
  
  1. Affiliated Hospital of Jining Medical College,Shandong
  2. Hebei Provincial People’s Hospital,Shijiazhuang
  3. Jining Medical College,Shandong
- Author bio：
- Funds：
- DOI：10.1007/BF02838559
  CLC：
- Published：2003，
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Jin-guo, Z., Dong-sheng, G., Na, Y. et al. Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction., Chin. J. Integr. Med. 9, 104–107 (2003). https://doi.org/10.1007/BF02838559

Zhang Jin-guo, Gao Dong-sheng, Yang Na, et al. Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction. [J]. Chinese Journal of Integrative Medicine 9(2):104-107(2003)
Jin-guo, Z., Dong-sheng, G., Na, Y. et al. Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction., Chin. J. Integr. Med. 9, 104–107 (2003). https://doi.org/10.1007/BF02838559 DOI：

Zhang Jin-guo, Gao Dong-sheng, Yang Na, et al. Effect of Astragalus Injection on left ventricular remodeling in aged patients with acute early-stage myocardial infarction. [J]. Chinese Journal of Integrative Medicine 9(2):104-107(2003) DOI： 10.1007/BF02838559.

摘要

Objective: To observe the effect of Astragalus Injection (AI) on left ventricular remodeling in aged patients with acute myocardial infarction (AMI).Methods: Patients with AMI were randomly divided into the AI group (46 cases) treated with AI and the control group (46 cases) treated conventionally. Left ventricular end-diastolic volume index (LVEDVI)

left ventricular end-systolic volume index (LVESVI)

anterior endocardial segmental length (ASL) and posterior endocardial segmental length (PSL) were all assessed by echocardiogram after 1 week and 4 weeks treatment. The cardiac systolic and diastolic functions were detected by nuclide gating cardiac blood pool imaging at the 4th week.Results: After four weeks’ treatment

no obvious change of LVEDVI

LVESVI and ASL in the AI group was found

but these indexes increased significantly in the control group

with significant difference shown between the two groups (P<0.05). As compared with the control group

the left ventricular ejection fraction (LVEF)

left ventricular peak ejecting rate (LVPER) and left ventricular peak filling rate (LVPFR) were heightened

the time for peak filling rate (LVTPFR) in the left ventricle was shortened in the AI group.Conclusion: AI is one of the effective drugs in reversing left ventricular remodeling in aged patients with AMI.

Abstract

left ventricular end-systolic volume index (LVESVI)

no obvious change of LVEDVI

LVESVI and ASL in the AI group was found

but these indexes increased significantly in the control group

with significant difference shown between the two groups (P<0.05). As compared with the control group

the left ventricular ejection fraction (LVEF)

left ventricular peak ejecting rate (LVPER) and left ventricular peak filling rate (LVPFR) were heightened

关键词

myocardial infarctionthe agedleft ventricular remodelingAstragalus Injection

Keywords

myocardial infarctionthe agedleft ventricular remodelingAstragalus Injection

references

Report of the Joint International Society and Federation of Cardiology/World Health Organization Task Force on Standardization of Clinical Nomenclature. Nomenclature and criteria for diagnosis of ischemic heart disease. Circulation 1979; 59(3): 607–609s.

ZENG Y, ZHU WL, NI C, et al. Effect of thrombolytic therapy in improving left ventricular function in patients with acute myocardial infarction. Chin J Cardiol 1997; 25(3): 192–194.

Editorial Board of Chinese Journal of Cardiology. Reference scheme of thrombolytic therapy conducted in acute myocardial infarction patients. Chin J Cardiol 1996; 24 (5): 328–340.

LIU JG, XU FM, DU WM, et al. Protective effect of Astragalus Injection on anesthetic dog with acute myocardial infarction. Chinese Traditional Patent Medicine 2001; 23(5): 351–353.

LUO HM, DAI RH, LI Y, et al. Nuclear cardiologic study on effective ingredients of Astragalus membraraceus in treating congestive heart failure. Chin J Integr Tradi &. West Med (Chin) 1995; 15(12): 707–709.

CHENG GR, YI SZ. Experimental study on rat’s myocardium protective effect pretreated with Astragalus membraraceus. Chin J Hypertension 2001; 9(4): 316–318.

WANG YS, DENG WL, XUE CS, edit. Pharmacology and Application of Chinese Materia Medica. Second edition. Beijing: People’s Publishing House of Health, 1998: 988–990.

REN P, CHENG ZH, MA YT, etal. Short-term effect of Astragalus Injection on hemodynamics in patients with congestive heart failure. Chin J Integr Tradi & West Med (Chin) 1998; 18(8): 460.

CHEN JC, LI SY, MIAO LJ, et al. Protective effect of Astragalus membraraceus on ultrastructure of in vitro cultured myocardial cells with ischemic, hypoxic, glucose deficit injury. New J TCM 1990; 22(3): 52–53.

HONG Y, XU SZ, ZENG DY, et al. Study of the inhibitory effect of Astragalus Injection on experimental cardiac hypertrophy in rats. Chin Tradi Patient Med 2002; 24(7): 525–529.

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Department of Cardiology, People’s Hospital of Hebei Province, Shijiazhang

Department of Cardiology, Affiliated Hospital of Jining Medical College

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Department of Cardiac Surgery, the First Affiliated Hospital, China Medical University

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