Effects of Kanlijian on exercise tolerance, quality of life, and frequency of heart failure aggravation in patients with chronic heart failure

Jiang Mei-xian; Ruan Xiao-fen; Xu Yan

doi:10.1007/BF02857353

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Effects of Kanlijian on exercise tolerance, quality of life, and frequency of heart failure aggravation in patients with chronic heart failure

Updated：2021-08-27

- Effects of Kanlijian on exercise tolerance, quality of life, and frequency of heart failure aggravation in patients with chronic heart failure
- Chinese Journal of Integrative Medicine Vol. 12, Issue 2, Pages: 94-100(2006)
- Affiliations：
  
  Department of Cardiovascular Diseases, Shuguang Hospital Affiliated to Shanghai University of TCM,Shanghai
- Author bio：
- Funds：
  
  Supported by the Item of Shanghai Municipal Ministry of Health on Standard for Quality Controling of Single Disease
- DOI：10.1007/BF02857353
  CLC：
- Published：2006，
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Mei-xian, J., Xiao-fen, R. & Yan, X. Effects of Kanlijian on exercise tolerance, quality of life, and frequency of heart failure aggravation in patients with chronic heart failure., Chin. J. Integr. Med. 12, 94–100 (2006). https://doi.org/10.1007/BF02857353

Jiang Mei-xian, Ruan Xiao-fen, Xu Yan. Effects of Kanlijian on exercise tolerance, quality of life, and frequency of heart failure aggravation in patients with chronic heart failure. [J]. Chinese Journal of Integrative Medicine 12(2):94-100(2006)
Mei-xian, J., Xiao-fen, R. & Yan, X. Effects of Kanlijian on exercise tolerance, quality of life, and frequency of heart failure aggravation in patients with chronic heart failure., Chin. J. Integr. Med. 12, 94–100 (2006). https://doi.org/10.1007/BF02857353 DOI：

Jiang Mei-xian, Ruan Xiao-fen, Xu Yan. Effects of Kanlijian on exercise tolerance, quality of life, and frequency of heart failure aggravation in patients with chronic heart failure. [J]. Chinese Journal of Integrative Medicine 12(2):94-100(2006) DOI： 10.1007/BF02857353.

摘要

Objective: To observe the effects of conventional therapy combined with Kanlijian (KLJ) on exercise tolerance

quality of life and frequency of heart failure aggravation in patients with chronic heart failure(CHF).Methods: Sixty CHF patients differentiated as sufferring from the syndrome of Xin-Shen Yang deficiency were included in the study and randomly assigned at the ratio of 2: 1 into the KLJ group (n = 39) and the control group(n = 21). All the patients were treated with conventional therapy of Western medicine

but to those in the KLJ group

KLJ was medicated additionally one dose daily with 24 wks as one therapeutic course. The efficacy on TCM syndrome and changes of scores on TCM syndrome were observed after treatment. The indexes

including 6-minute walking distance (6MWD)

quality of life (QOL

accessed by LHFQ scoring)

NYHA grade

hemodynamic indexes and reducing/withdrawal rate of diuretic and digoxin before and after treatment were recorded and compared. Also the frequency of re-admission due to aggravation of heart failure in one year’s time were observed.Results: (1) The efficacy on TCM syndrome

improvement on scores of TCM syndrome

therapeutic effects on 6MWD

QOL

and NYHA grade in the KLJ group were superior to those in the control group. (2) Hemodynamic indexes after treatment

left ventricular fractional shortening (LVFS) and E peak/A peak (E/A)

between the two groups had no significant difference

while left ventricular ejection fraction (LVEF) was increased significantly in the KLJ group

but with no obvious change in the control group. (3) The reducing/withdrawal rate of diuretic and digoxin in the KLJ group was significantly higher than that in the control group. (4) The 1-year frequency of re-admission significantly decreased in the KLJ group.Conclusion: The adjuvant treatment of KLJ on the basis of Western conventional therapy can significantly improve CHF patients’ exercise tolerance

quality of life and cardiac function

reduce the dosage of diuretic and digoxin needed

and decrease the re-admission frequency due to aggravation of heart failure.

Abstract

Objective: To observe the effects of conventional therapy combined with Kanlijian (KLJ) on exercise tolerance

but to those in the KLJ group

KLJ was medicated additionally one dose daily with 24 wks as one therapeutic course. The efficacy on TCM syndrome and changes of scores on TCM syndrome were observed after treatment. The indexes

including 6-minute walking distance (6MWD)

quality of life (QOL

accessed by LHFQ scoring)

NYHA grade

improvement on scores of TCM syndrome

therapeutic effects on 6MWD

QOL

and NYHA grade in the KLJ group were superior to those in the control group. (2) Hemodynamic indexes after treatment

left ventricular fractional shortening (LVFS) and E peak/A peak (E/A)

between the two groups had no significant difference

while left ventricular ejection fraction (LVEF) was increased significantly in the KLJ group

quality of life and cardiac function

reduce the dosage of diuretic and digoxin needed

and decrease the re-admission frequency due to aggravation of heart failure.

关键词

Kanlijianchronic heart failureexercise tolerancequality of lifeaggravation of heart failure

Keywords

Kanlijianchronic heart failureexercise tolerancequality of lifeaggravation of heart failure

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