Thermodynamic study on antibacterial effect of different extracts from Radix Isatis

Zhao Yan-ling; Qu Fen; Xiao Xiao-he; Liao Qing-wen; Wang Jia-bo; Ma Yong-gang; Sun Yu-qi

doi:10.1007/BF02857429

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Thermodynamic study on antibacterial effect of different extracts from Radix Isatis

Updated：2021-08-27

- Thermodynamic study on antibacterial effect of different extracts from Radix Isatis
- Chinese Journal of Integrative Medicine Vol. 12, Issue 1, Pages: 42-45(2006)
- Affiliations：
  
  1. Institute of Chinese Materia Medica, The Hospital of PLA,Beijing,302
  2. Academy of Military Medical Science,China
  3. Clinical Laboratory, the Hospital of PLA,China,302
- Author bio：
- Funds：
  
  Supported by Foundation of State Administration of Traditional Chinese Medicine (No. 04-05ZP70)
- DOI：10.1007/BF02857429
  CLC：
- Published：2006，
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Yan-ling, Z., Fen, Q., Xiao-he, X. et al. Thermodynamic study on antibacterial effect of different extracts from Radix Isatis., Chin. J. Integr. Med. 12, 42–45 (2006). https://doi.org/10.1007/BF02857429

Zhao Yan-ling, Qu Fen, Xiao Xiao-he, et al. Thermodynamic study on antibacterial effect of different extracts from Radix Isatis. [J]. Chinese Journal of Integrative Medicine 12(1):42-45(2006)
Yan-ling, Z., Fen, Q., Xiao-he, X. et al. Thermodynamic study on antibacterial effect of different extracts from Radix Isatis., Chin. J. Integr. Med. 12, 42–45 (2006). https://doi.org/10.1007/BF02857429 DOI：

Zhao Yan-ling, Qu Fen, Xiao Xiao-he, et al. Thermodynamic study on antibacterial effect of different extracts from Radix Isatis. [J]. Chinese Journal of Integrative Medicine 12(1):42-45(2006) DOI： 10.1007/BF02857429.

摘要

Objective: To study and analyze the antibacterial effects of different extracts from Radix Isatis.Methods: Staphylococcus aureus was used as the studied object in the experiment. Antibacterial effects of extracts from Radix Isatis were observed by thermocalrimetry on Staphylococcus aureus

together with common pharmacological experiments.Results: The total extract

ethyl acetate (EtOAc) extract

n-butylalcohol (nBuOH) extract

chloroform (CHCl3) extract and petroleum (P.E.) extract had antiviral effects to some extent while the residue after extracting had no antibacterial activity. The potency of antiviral activity among them was as follows: nBuOH extract > EtOAc extract > CHCl3 extract> total extract >P. E. extract.Conclusion: The antibacteriall effects of Radix Isatis were not limited to any active portion

showing that Radix Isatis exerts its antibacterial effects by cooperation of different active fractions in varied ways.

Abstract

together with common pharmacological experiments.Results: The total extract

ethyl acetate (EtOAc) extract

n-butylalcohol (nBuOH) extract

showing that Radix Isatis exerts its antibacterial effects by cooperation of different active fractions in varied ways.

关键词

Radix Isatisthermodynamicsantibacterial effect

Keywords

Radix Isatisthermodynamicsantibacterial effect

references

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Yang Y, Liu Y, Zhu J, et al. Microcalorimetric study on the transcription start site mutagenesis. J Thermal Analysis Calorimetry 2004; 75(3): 293–300.

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Yan CG, Xie XY, Liu Y, et al. Survey of thermochemistry on characteristics of bacteria metabolism. Acta Hubei Agriculture Coll 1997; 17(3): 229–232.

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