Improvement of quality of life with Shenfu injection in non small cell lung cancer patients treated with gemcitabine plus cisplatin regimen

Wu Wan-yin; Long Shun-qin; Zhang Hai-bo; Chai Xiao-shu; Deng Hong; Xue Xiao-guang; Wang Bin; Luo Hai-ying; Liu Wei-sheng

doi:10.1007/BF02857431

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Improvement of quality of life with Shenfu injection in non small cell lung cancer patients treated with gemcitabine plus cisplatin regimen

Updated：2021-08-27

- Improvement of quality of life with Shenfu injection in non small cell lung cancer patients treated with gemcitabine plus cisplatin regimen
- Chinese Journal of Integrative Medicine Vol. 12, Issue 1, Pages: 50-54(2006)
- Affiliations：
  
  Department of Cancer, Guangdong Provincial Traditional Chinese Medicine Hospital,Guangzhou
- Author bio：
- Funds：
  
  Supported by the “999” Shenfu Injection Foundation sponsored by China National Health Ministry and Canadian Terry Fox Foundation for Cancer Research
- DOI：10.1007/BF02857431
  CLC：
- Published：2006，
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Wan-yin, W., Shun-qin, L., Hai-bo, Z. et al. Improvement of quality of life with Shenfu injection in non small cell lung cancer patients treated with gemcitabine plus cisplatin regimen., Chin. J. Integr. Med. 12, 50–54 (2006). https://doi.org/10.1007/BF02857431

Wu Wan-yin, Long Shun-qin, Zhang Hai-bo, et al. Improvement of quality of life with Shenfu injection in non small cell lung cancer patients treated with gemcitabine plus cisplatin regimen. [J]. Chinese Journal of Integrative Medicine 12(1):50-54(2006)
Wan-yin, W., Shun-qin, L., Hai-bo, Z. et al. Improvement of quality of life with Shenfu injection in non small cell lung cancer patients treated with gemcitabine plus cisplatin regimen., Chin. J. Integr. Med. 12, 50–54 (2006). https://doi.org/10.1007/BF02857431 DOI：

Wu Wan-yin, Long Shun-qin, Zhang Hai-bo, et al. Improvement of quality of life with Shenfu injection in non small cell lung cancer patients treated with gemcitabine plus cisplatin regimen. [J]. Chinese Journal of Integrative Medicine 12(1):50-54(2006) DOI： 10.1007/BF02857431.

摘要

Objective: To observe the effect of Shenfu injection (SFI) in treating non small cell lung cancer (NSCLC) patients on quality of life with gemcitabine (GEM) plus cisplatin (GP) regimen.Methods: Thirty-four patients were ready to receive GP regimen chemotherapy for treating NSCLC disease

according to lot-drawing

they were divided into SFI pre-treatment group (18 cases) and SFI post-treatment group (16 cases). SFI pre-treatment group: During the first treatment course

chemotherapy was begun with SFI 60 ml

intravenous dripping on the 3rd day

once daily

consecutively for 10 days; on the 1st day

GP regimen (GEM 1250 mg/m2

intravenous dripping

on the 1st and 8th day; cisplatin 70 mg/m2 on the 2nd day; 21 days as one cycle) was carried out; in the second treatment course GP regimen was merely given to serve as the self-control. SFI post-treatment group: the medicament sequence order was reversed from that of pre-treatment group. Using dual international quality of life (QOL) scores

the effect of SFI on the patients’ QOL was observed through randomized self preand postcrossover control.Results: The QOL in the 34 patients after being treated by SFI in combination with GP chemotherapy regimen in one group

and GP chemotherapy regimen alone in the other

was improved in different degrees

with significant difference (P< 0.01); comparision of SFI combined with GP chemotherapy regimen with GP chemotherapy alone showed that QOL in patients was significantly different (P<0.01).Conclusion: SFI could improve QOL in patients with NSCLC who were treated with GP regimen.

Abstract

according to lot-drawing

they were divided into SFI pre-treatment group (18 cases) and SFI post-treatment group (16 cases). SFI pre-treatment group: During the first treatment course

chemotherapy was begun with SFI 60 ml

intravenous dripping on the 3rd day

once daily

consecutively for 10 days; on the 1st day

GP regimen (GEM 1250 mg/m2

intravenous dripping

and GP chemotherapy regimen alone in the other

was improved in different degrees

关键词

Shenfu Injectionnon small cell lung cancergemcitabinecisplatinquality of life

Keywords

Shenfu Injectionnon small cell lung cancergemcitabinecisplatinquality of life

references

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