Clinical and experimental study on treatment of Psoriasis Maculata by Leyin

Hong-pu Yang; Ren-jie Hu; Yun Qi; Li-min Xu; Shu-fang Qiao

doi:10.1007/BF02934398

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Clinical and experimental study on treatment of Psoriasis Maculata by Leyin

Updated：2021-08-27

- Clinical and experimental study on treatment of Psoriasis Maculata by Leyin
- Chinese Journal of Integrative Medicine Vol. 8, Issue 4, Pages: 256-261(2002)
- Affiliations：
  
  1. Department of Skin Diseases, Changzheng Hospital,Tianjin
  2. Tianjin Municipal Institute of Medical Sciences,Tianjin
- Author bio：
- Funds：
  
  This article is supported by the fund of Integrated Chinese Traditional and Western Medicine from Health Bureau of Tianjin City (No. 98012)
- DOI：10.1007/BF02934398
  CLC：
- Published：2002，
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Yang, Hp., Hu, Rj., Qi, Y. et al. Clinical and experimental study on treatment of Psoriasis Maculata by Leyin., CJIM 8, 256–261 (2002). https://doi.org/10.1007/BF02934398

Hong-pu Yang, Ren-jie Hu, Yun Qi, et al. Clinical and experimental study on treatment of Psoriasis Maculata by Leyin. [J]. Chinese Journal of Integrative Medicine 8(4):256-261(2002)
Yang, Hp., Hu, Rj., Qi, Y. et al. Clinical and experimental study on treatment of Psoriasis Maculata by Leyin., CJIM 8, 256–261 (2002). https://doi.org/10.1007/BF02934398 DOI：

Hong-pu Yang, Ren-jie Hu, Yun Qi, et al. Clinical and experimental study on treatment of Psoriasis Maculata by Leyin. [J]. Chinese Journal of Integrative Medicine 8(4):256-261(2002) DOI： 10.1007/BF02934398.

摘要

To observe the therapeutic effect of Leyin (

LY) in treating psoriasis maculata (PM) and its effects on cellular immunity and vaginal epithelial cell mitosis in experimental mice. In this clinical study

260 out-patients of PM were randomly divided into the observed group (n =160) and the control group (n=100)

who were treated with oral intake of LY and Yinxieling granule (YXL

) respectively to observe the therapeutic effect and the adverse reaction. And a follow-up study was also conducted on them. In the experimental study

delayed allergic model mice were treated with immunosuppressor (cyclophosphamide) and LY separately to observe the effects on their immune function and inhibition of vaginal epithelial cell proliferation. In the observed group

8 patients (5%) were cured

32 (20%) basically cured

48 (30%) markedly improved

48 (30%) improved and 24 (15%) unchanged

the total effective rate being 85%

while in the control group

the corresponding numbers were 4

36 and 64% respectively

with the comparison of the total effective rate between the two groups showing significant difference(P<0. 01) . Adverse reactions were not found in the study. Experimental study showed that LY could enhance the immune function of mice and had a certain inhibitory effect on vaginal epithelial cell proliferation. LY could treat PM effectively and shows immune enhancing and anti-mitosis effect in mice.

Abstract

To observe the therapeutic effect of Leyin (

LY) in treating psoriasis maculata (PM) and its effects on cellular immunity and vaginal epithelial cell mitosis in experimental mice. In this clinical study

260 out-patients of PM were randomly divided into the observed group (n =160) and the control group (n=100)

who were treated with oral intake of LY and Yinxieling granule (YXL

) respectively to observe the therapeutic effect and the adverse reaction. And a follow-up study was also conducted on them. In the experimental study

8 patients (5%) were cured

32 (20%) basically cured

48 (30%) markedly improved

48 (30%) improved and 24 (15%) unchanged

the total effective rate being 85%

while in the control group

the corresponding numbers were 4

36 and 64% respectively

关键词

Leyinmacular psoriasiscellular immunitymice

Keywords

Leyinmacular psoriasiscellular immunitymice

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