Effect of dachengqi granules on level of endotoxin in enterogenous endotoxemia in rats

Xiu-zhen Lin; Yao Zheng; De-lu Ma; Wen-li Xie; Shan Zhao; Xian-zhong Wu

doi:10.1007/BF02934413

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Effect of dachengqi granules on level of endotoxin in enterogenous endotoxemia in rats

Updated：2021-08-27

- Effect of dachengqi granules on level of endotoxin in enterogenous endotoxemia in rats
- Chinese Journal of Integrative Medicine Vol. 8, Issue 4, Pages: 299-301(2002)
- Affiliations：
  
  Department of Pharmacology, Tianjin Medical University,Tianjin,China
- Author bio：
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- DOI：10.1007/BF02934413
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- Published：2002，
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Lin, Xz., Zheng, Y., Ma, Dl. et al. Effect of dachengqi granules on level of endotoxin in enterogenous endotoxemia in rats., CJIM 8, 299 (2002). https://doi.org/10.1007/BF02934413

Xiu-zhen Lin, Yao Zheng, De-lu Ma, et al. Effect of dachengqi granules on level of endotoxin in enterogenous endotoxemia in rats. [J]. Chinese Journal of Integrative Medicine 8(4):299-301(2002)
Lin, Xz., Zheng, Y., Ma, Dl. et al. Effect of dachengqi granules on level of endotoxin in enterogenous endotoxemia in rats., CJIM 8, 299 (2002). https://doi.org/10.1007/BF02934413 DOI：

Xiu-zhen Lin, Yao Zheng, De-lu Ma, et al. Effect of dachengqi granules on level of endotoxin in enterogenous endotoxemia in rats. [J]. Chinese Journal of Integrative Medicine 8(4):299-301(2002) DOI： 10.1007/BF02934413.

摘要

To study the effect of Dachengqi Granule (DCQG) on endotoxin level in rats of enterogenous endotoxemia. Enterogenous endotoxemia model of rats was made by peritoneal injection of E. coli. In the treated groups

the rats were treated with different doses of DCQG

cefaclor and DCQG plus cefaclor respectively

starting from 3 days before to 1 day after modeling. Endotoxin levels in plasma

urine and stool were determined and compared. Except for the cefaclor group

the plasma and urine endotoxin levels in the treated groups were lower significantly (P<0.05)

while the endotoxin level in stool was obviously higher than that in the untreated model group. DCQG has the intestinal barrier protective effect including anti-bacteria

anti-inflammation and clearing endotoxin.

Abstract

the rats were treated with different doses of DCQG

cefaclor and DCQG plus cefaclor respectively

starting from 3 days before to 1 day after modeling. Endotoxin levels in plasma

urine and stool were determined and compared. Except for the cefaclor group

the plasma and urine endotoxin levels in the treated groups were lower significantly (P<0.05)

while the endotoxin level in stool was obviously higher than that in the untreated model group. DCQG has the intestinal barrier protective effect including anti-bacteria

anti-inflammation and clearing endotoxin.

关键词

Dachengqi Granuleenterogenous endotoxemiaendotoxinrat

Keywords

Dachengqi Granuleenterogenous endotoxemiaendotoxinrat

references

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