Effect of Xin’ anning Nasal Drop (心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris

Wang  Zhong-liang; Qian Shi-ming; Zhang Han-mei

doi:10.1007/s11655-001-0301-z

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Effect of Xin’ anning Nasal Drop (心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris

Updated：2021-08-27

- Effect of Xin’ anning Nasal Drop (心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris
- Chinese Journal of Integrative Medicine Vol. 12, Issue 4, Pages: 301-305(2006)
- Affiliations：
  
  1. Department of Cardiopathy, TCM Hospital of Xuzhou City,Jiangsu,China
  2. Nanjing University of TCM,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-001-0301-z
  CLC：
- Published：2006，
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Wang, Zl., Qian, Sm. & Zhang, Hm. Effect of Xin’ anning Nasal Drop (心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris., Chin. J Integ. Med. 12, 301–305 (2006). https://doi.org/10.1007/s11655-001-0301-z

Wang Zhong-liang, Qian Shi-ming, Zhang Han-mei. Effect of Xin’ anning Nasal Drop (心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris. [J]. Chinese Journal of Integrative Medicine 12(4):301-305(2006)
Wang, Zl., Qian, Sm. & Zhang, Hm. Effect of Xin’ anning Nasal Drop (心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris., Chin. J Integ. Med. 12, 301–305 (2006). https://doi.org/10.1007/s11655-001-0301-z DOI：

Wang Zhong-liang, Qian Shi-ming, Zhang Han-mei. Effect of Xin’ anning Nasal Drop (心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris. [J]. Chinese Journal of Integrative Medicine 12(4):301-305(2006) DOI： 10.1007/s11655-001-0301-z.

摘要

To observe the clinical efficacy of Xin’ anning Nasal Drop (XAND

心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris (CHD-UAP). Sixty patients with CHD-UAP were assigned

according to the randomizing number table

to two groups

the control group treated with conventional Western medicine

and the treated group treated with conventional Western medicine plus XAND. The clinical efficacy and the changes of S-T segment in resting EKG and total ischemia burden (TIB) in 24-h dynamic EKG were observed. The clinical efficacy

including the effect of angina alleviation

its initiation

and the effect of TCM syndrome score reduction

were significantly superior in the treated group to those in the control group (P<0.05 or P<0.01). The degree and extent of myocardial ischemia were significantly improved in both groups (P<0.01)

but the improvement in the treated group was better than that in the control group (P<0.05). Moreover

it was worth mentioning that the immediate effect in the treated group was better than that in the control group

and the reduction of TIB

the improvement in heart rate and myocardial oxygen consumption (immediately after the first administration or by the end of the therapeutic course)

and systolic blood pressure after treatment in the former were all superior to those in the latter

showing significant difference (P<0.05 or P<0.01). XAND has a quick effect in alleviating angina in patients with CHD-UAP

and it is worthy of furtherstudies and spreading in clinical practice.

Abstract

To observe the clinical efficacy of Xin’ anning Nasal Drop (XAND

心安宁滴鼻剂) in treating coronary heart disease with unstable angina pectoris (CHD-UAP). Sixty patients with CHD-UAP were assigned

according to the randomizing number table

to two groups

the control group treated with conventional Western medicine

including the effect of angina alleviation

its initiation

and the effect of TCM syndrome score reduction

were significantly superior in the treated group to those in the control group (P<0.05 or P<0.01). The degree and extent of myocardial ischemia were significantly improved in both groups (P<0.01)

but the improvement in the treated group was better than that in the control group (P<0.05). Moreover

it was worth mentioning that the immediate effect in the treated group was better than that in the control group

and the reduction of TIB

the improvement in heart rate and myocardial oxygen consumption (immediately after the first administration or by the end of the therapeutic course)

and systolic blood pressure after treatment in the former were all superior to those in the latter

showing significant difference (P<0.05 or P<0.01). XAND has a quick effect in alleviating angina in patients with CHD-UAP

and it is worthy of furtherstudies and spreading in clinical practice.

关键词

unstable angina pectorisXin’ anning Nasal DropClinical Study

Keywords

unstable angina pectorisXin’ anning Nasal DropClinical Study

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