Study on clinical effect and mechanism of Jianpi Qingre Huayu Recipe (健脾清热化瘀方) in treating patients with gastric ulcer

Zhou  Fu-sheng; Hu Li-Juan; Wang Ru-jun; Huang Zhi-xin; Luo Qi

doi:10.1007/s11655-007-0022-z

Your Location：

Home >

Browse articles >

Study on clinical effect and mechanism of Jianpi Qingre Huayu Recipe (健脾清热化瘀方) in treating patients with gastric ulcer

Updated：2021-08-27

- Study on clinical effect and mechanism of Jianpi Qingre Huayu Recipe (健脾清热化瘀方) in treating patients with gastric ulcer
- Chinese Journal of Integrative Medicine Vol. 13, Issue 1, Pages: 22-26(2007)
- Affiliations：
  
  1. wei Institute of Guangzhou University of Traditional Chinese Medicine, Guangzhou,Pi,China
  2. Guangzhou University of Traditional Chinese Medicine,China
- Author bio：
- Funds：
  
  Supported by Guangdong Provincial Committee of Science and Technology, Project number 6
- DOI：10.1007/s11655-007-0022-z
  CLC：
- Published：2007，
Scan for full text
Zhou, Fs., Hu, LJ., Wang, Rj. et al. Study on clinical effect and mechanism of Jianpi Qingre Huayu Recipe (健脾清热化瘀方) in treating patients with gastric ulcer., Chin. J Integ. Med. 13, 22–26 (2007). https://doi.org/10.1007/s11655-007-0022-z

Zhou Fu-sheng, Hu Li-Juan, Wang Ru-jun, et al. Study on clinical effect and mechanism of Jianpi Qingre Huayu Recipe (健脾清热化瘀方) in treating patients with gastric ulcer. [J]. Chinese Journal of Integrative Medicine 13(1):22-26(2007)
Zhou, Fs., Hu, LJ., Wang, Rj. et al. Study on clinical effect and mechanism of Jianpi Qingre Huayu Recipe (健脾清热化瘀方) in treating patients with gastric ulcer., Chin. J Integ. Med. 13, 22–26 (2007). https://doi.org/10.1007/s11655-007-0022-z DOI：

Zhou Fu-sheng, Hu Li-Juan, Wang Ru-jun, et al. Study on clinical effect and mechanism of Jianpi Qingre Huayu Recipe (健脾清热化瘀方) in treating patients with gastric ulcer. [J]. Chinese Journal of Integrative Medicine 13(1):22-26(2007) DOI： 10.1007/s11655-007-0022-z.

摘要

To study the effects of Jianpi Qingre Huayu Recipe (健脾清热化瘀方

JQH) in curing gastric ulcer and to preliminarily probe into its pathogenic mechanism. Fifty patients with gastric ulcer of Pi (脾)-insufficiency and stasis-heat syndrome type were assigned to the treated group (30 patients) and the control group (20 patients). They were treated respectively with JQH and Ranitidine. At the same time

another group consisting of 20 healthy persons was set up for normal control. The clinical effect on gastroscopic figure and traditional Chinese medicine (TCM) syndrome were observed. Changes of T-cell subsets and interleukin-8 (IL-8) in serum as well as IL-8 in mucosa around the gastric ulcer were determined before and after treatment by flow cytometry and ELISA. Comparison of the total effective rate on gastroscopic figure in the treated group and the control group (86.7% vs 80.0%) showed insignificant difference

but the cure rate and markedly effective rate in the former (50.0% and 20.0%) was higher than that in the latter (40.0% and 15.0%) respectively. Comparison of the total effective rate on TCM syndrome in the treated group and in the control group (96.7% vs 70.0%) showed insignificant difference

but the cure rate and markedly effective rate in the former (63.3% and 23.3%) was higher than that in the latter (50.0% and 20.0%) respectively. Serum levels of CD3 +

CD4 +

CD8 + got restored to normal range in the treated group after treatment but it was not so in the control group. IL-8 level in gastric mucosa was improved in both groups but the improvement in the treated group was better. JQH could effectively treat gastric ulcer and partly reduce its recurrence through improving patients’ immune function.

Abstract

To study the effects of Jianpi Qingre Huayu Recipe (健脾清热化瘀方

but the cure rate and markedly effective rate in the former (63.3% and 23.3%) was higher than that in the latter (50.0% and 20.0%) respectively. Serum levels of CD3 +

CD4 +

关键词

Jianpi Qingre Huayu RecipeT-cell subsetsinterleukin-8

Keywords

Jianpi Qingre Huayu RecipeT-cell subsetsinterleukin-8

references

Wang ZT, Dong GL, Wang WZ. The effects of Kang Lai-te on apoptosis and proliferation of advanced gastric cancer patients. Chin J Cell Mol Immun 2002;18(5):463–465.

Committee of New Drug of Traditional Chinese Drugs Clinical Study Instruction Principle. New drug of traditional Chinese clinical study instruction principle. Beijing: People’s Medical Publishing House, 2002:123–125.

Guangxi Medical Science Information Institute. Standard of diseases diagnosis and treatment. Nanning: Guangxi People’s Medical Publishing House, 1993:606.

Xu GM, Li ZS. Training textbook of endoscope. Shanghai: Shanghai Sience and Technology Publishing Company, 2002:115–118.

Zheng QJ, Cai ZJ, Yu SQ, et al. Effect of FK506 combinated with resveratrol on T-cell subsets and its ummune function following homologous heart transplantation. China J Mordern Med 2005;15(20):3099–3101.

Gao SP, Tang HJ, Jia XH, et al. The effect of immunity of Prescription Runing II to breast cance surgery patients and mouse with cancer. Chin J Tradit Med Sci Technol 2003;10(5):261–262.

Zhang XN. Treatment method of replenishment Pi to prevent “easy to suffer from a disease”. Liaoning J Tradit Chin Med 1993;4(1):29.

Huang SG, Zhou FS, Wang RJ, et al. A study of traditional Chinese medicine pathogen of gastric ulcer and recurrence. New J Tradit Chin Med 2005;37(3):6–7.

Wu XC, Du SL, Cheng HS. Study and application of Dandelion herb. J Pharm Practice 2002;20(4):246–248.

Wang GM, Ma XQ. Clinic application of Red sage root. China’s Naturopathy 2003;11(12):51–52.

Zhou FS, Hu L, Cui QZ, et al. A mechanic study of traditional Chinese medicine in treating ulcer recurrence. Chin J Integr Tradit West Med 2001;21(3):231–234.

FULL TEXT LINK

More>

Views

326

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

A randomized controlled trial comparing total glucosides of paeony capsule and compound glycyrrhizin tablet for alopecia areata

Effect of puerarin on the release of interleukin-8 in co-culture of human bronchial epithelial cells and neutrophils

Tumor interstitial fluid and postoperative recurrence of tumors: An experimental study for verifying hypothesis of “tumor-phlegm microenvironment”

Effect of Tanreqing Injection (痰热清注射液) on treatment of acute exacerbation of chronic obstructive pulmonary disease with Chinese medicine syndrome of retention of phlegm and heat in Fei (肺)

Effect of Yufeining on induced sputum interleukin-8 in patients with chronic obstructive pulmonary disease at the stable phase

Related Author

No data

Related Institution

Department of Dermatology, China-Japan Friendship Hospital

Department of Clinical Laboratory Medicine, Affiliate Hospital of Logistical College of Chinese People’s Armed Police Forces

Department of Clinical Laboratory Medicine, Chinese People’s Liberation Army General Hospital and Postgraduate Medical School

Department of Pathology, Shanghai Changzheng Hospital, the Second Military Medical University

Department of Laboratory Digniostics, Shanghai Changzheng Hospital, the Second Military Medical University

Address：1 Caochang, xiyuan, Beijing, People's Republic of China Postal code：100091
Tel：010-62886827, 62877592 Fax：010-62874291
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05067934号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰