Study of Qingre Liyan Decoction (清热利咽汤) in treating and preventing acute radioactive oral mucositis

Wu Min-hui; Yuan Bin; Liu Qiu-fang; Wang Qian

doi:10.1007/s11655-007-0280-9

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Study of Qingre Liyan Decoction (清热利咽汤) in treating and preventing acute radioactive oral mucositis

Updated：2021-08-27

- Study of Qingre Liyan Decoction (清热利咽汤) in treating and preventing acute radioactive oral mucositis
- Chinese Journal of Integrative Medicine Vol. 13, Issue 4, Pages: 280-284(2007)
- Affiliations：
  
  Department of Integrative Medicine, Shaanxi Province Oncology Hospital,Xi’an,China
- Author bio：
- Funds：
  
  Supported by the Foundation Item of Shaanxi Provincial Administration of Traditional Chinese Medicine (No.0331)
- DOI：10.1007/s11655-007-0280-9
  CLC：
- Published：2007，
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Wu, Mh., Yuan, B., Liu, Qf. et al. Study of Qingre Liyan Decoction (清热利咽汤) in treating and preventing acute radioactive oral mucositis., Chin. J. Integr. Med. 13, 280–284 (2007). https://doi.org/10.1007/s11655-007-0280-9

Wu Min-hui, Yuan Bin, Liu Qiu-fang, et al. Study of Qingre Liyan Decoction (清热利咽汤) in treating and preventing acute radioactive oral mucositis. [J]. Chinese Journal of Integrative Medicine 13(4):280-284(2007)
Wu, Mh., Yuan, B., Liu, Qf. et al. Study of Qingre Liyan Decoction (清热利咽汤) in treating and preventing acute radioactive oral mucositis., Chin. J. Integr. Med. 13, 280–284 (2007). https://doi.org/10.1007/s11655-007-0280-9 DOI：

Wu Min-hui, Yuan Bin, Liu Qiu-fang, et al. Study of Qingre Liyan Decoction (清热利咽汤) in treating and preventing acute radioactive oral mucositis. [J]. Chinese Journal of Integrative Medicine 13(4):280-284(2007) DOI： 10.1007/s11655-007-0280-9.

摘要

To study the effect of Qingre Liyan Decoction (清热利咽汤

QRLYD) in the prevention and treatment of acute radiative oral mucositis (AROM)

and to explore the mechanism of QRLYD by detecting epidermal growth factor (EGF) and T lymphocytes (CD3

CD4

and CD8). Sixty patients conforming with the standard were randomly assigned to two groups

30 patients in each group. Patients in the trial group were treated with QRLYD

and those in the control group were treated with Dobell’s solution

both groups receiving conventional radiation treatment. The treatment course for both groups was 6 weeks on average. Blood routine test

CD3

CD4

and CD8 in the peripheral blood and EGF in the saliva were detected one day before and on the 14th and 28th day of radio-therapy. Patients in the trial group were in good condition with normal spirits and intake of food and drinks. The incidence of AROM is lower and the effect in preventing AROM is higher in the trial group than those in the control group (P<0.05). The EGF in saliva

and CD4 and CD8 in the blood of patients in the trial group were higher than those in the control group (P<0.05). QRLYD can cure and prevent AROM. The mechanism may be related with its effects in enhancing body immunity and promoting salivary EGF.

Abstract

To study the effect of Qingre Liyan Decoction (清热利咽汤

QRLYD) in the prevention and treatment of acute radiative oral mucositis (AROM)

and to explore the mechanism of QRLYD by detecting epidermal growth factor (EGF) and T lymphocytes (CD3

CD4

and CD8). Sixty patients conforming with the standard were randomly assigned to two groups

30 patients in each group. Patients in the trial group were treated with QRLYD

and those in the control group were treated with Dobell’s solution

both groups receiving conventional radiation treatment. The treatment course for both groups was 6 weeks on average. Blood routine test

CD3

CD4

关键词

Qingre Liyan Decoctionacute radiative oral mucositisepidermal growth factorT lymphocytes

Keywords

Qingre Liyan Decoctionacute radiative oral mucositisepidermal growth factorT lymphocytes

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Fujian Medical University

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Department of Digestive Medicine, The Second Affiliated Hospital of Medical College, Xi’an Jiaotong University

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Institute of Nephrology, Jinling Hospital

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