Effect of mica monomer powder on chief and parietal cells as well as G and D cells in gastric mucosa of chronic atrophic gastritis in rats

Fang-shi Zhu; Jian-min Si; Liang-jing Wang; Dong-fei Wang; Ping Cheng

doi:10.1007/s11655-007-9003-5

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Effect of mica monomer powder on chief and parietal cells as well as G and D cells in gastric mucosa of chronic atrophic gastritis in rats

Updated：2021-08-27

- Effect of mica monomer powder on chief and parietal cells as well as G and D cells in gastric mucosa of chronic atrophic gastritis in rats
- Chinese Journal of Integrative Medicine Vol. 14, Issue 2, Pages: 111-116(2008)
- Affiliations：
  
  1. Academy of Traditional Chinese Medicine of Jiangsu Province,Nanjing,China
  2. Sir Run Run Shaw Clinical Medical Institute, Zheijiang University, Zheijiang,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-007-9003-5
  CLC：
- Published：2008，
  
  Published Online：6 August 2008，
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Zhu, Fs., Si, Jm., Wang, Lj. et al. Effect of mica monomer powder on chief and parietal cells as well as G and D cells in gastric mucosa of chronic atrophic gastritis in rats., Chin. J. Integr. Med. 14, 111–116 (2008). https://doi.org/10.1007/s11655-007-9003-5

Fang-shi Zhu, Jian-min Si, Liang-jing Wang, et al. Effect of mica monomer powder on chief and parietal cells as well as G and D cells in gastric mucosa of chronic atrophic gastritis in rats. [J]. Chinese Journal of Integrative Medicine 14(2):111-116(2008)
Zhu, Fs., Si, Jm., Wang, Lj. et al. Effect of mica monomer powder on chief and parietal cells as well as G and D cells in gastric mucosa of chronic atrophic gastritis in rats., Chin. J. Integr. Med. 14, 111–116 (2008). https://doi.org/10.1007/s11655-007-9003-5 DOI：

Fang-shi Zhu, Jian-min Si, Liang-jing Wang, et al. Effect of mica monomer powder on chief and parietal cells as well as G and D cells in gastric mucosa of chronic atrophic gastritis in rats. [J]. Chinese Journal of Integrative Medicine 14(2):111-116(2008) DOI： 10.1007/s11655-007-9003-5.

摘要

To study the regulative action of mica monomer powder preparation on the chief and parietal cells as well as G and D cells in the gastric mucosa of the experimental atrophic gastritis (CAG) rats. Intervention therapy was given to the experimental CAG rats at three different doses of mica monomer powder preparation to evaluate the changes of chief and parietal cells as well as G and D cells in the gastric mucosa and the histopathological changes of gastric mucosa. Mica monomer powder preparation at three different doses could increase the amount of chief and parietal cells as well as G and D cells in gastric mucosa of the experimental CAG rats and alleviate and control the inflammation of gastric mucosa and the atrophy of gastric mucosa glands. Especially

better effects were shown in the mid and high dose groups. Mica has the pharmacological action of protecting the gastric mucosa

promoting the regeneration of gastric glands

enhancing blood flow of the gastric mucosa

and consequently improving the inflammatory responses of the gastric mucosa. One of the mechanisms is associated with promoting the secretion of gastric acid and gastric pepsin and regulating the neuroendocrine mechanism including gut hormone secretion (gastrin and somatostatin) by increasing the number of chief and parietal cells as well as G and D cells.

Abstract

better effects were shown in the mid and high dose groups. Mica has the pharmacological action of protecting the gastric mucosa

promoting the regeneration of gastric glands

enhancing blood flow of the gastric mucosa

关键词

micaChronic Atrophic Gastritischief cellparietal cellG cellD cell

Keywords

micaChronic Atrophic Gastritischief cellparietal cellG cellD cell

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Institute of Digestive Diseases, Jiangsu Provincial Hospital of Traditional Chinese Medicine

Department of Pathology, Jiangsu Provincial Hospital of TCM

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