Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure

Xi-li Wu; Wan-sen Sun; Wang-gang Zhang; Cheng-lin Qiao; Run-xia Liu

doi:10.1007/s11655-008-0098-0

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Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure

Updated：2021-08-27

- Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure
- Chinese Journal of Integrative Medicine Vol. 14, Issue 2, Pages: 98-102(2008)
- Affiliations：
  
  1. Department of the Integrated Chinese and Western Medicine, Shaanxi Province Traditional Chinese Medical Key Department of Nephrology, Second Affiliated Hospital, Medical School of Xi’an Jiaotong University,Xi’an,China
  2. Department of Hematology, Second Affiliated Hospital, Medical School of Xi’an Jiaotong University,Xi’an,China
- Author bio：
- Funds：
- DOI：10.1007/s11655-008-0098-0
  CLC：
- Published：2008，
  
  Published Online：6 August 2008，
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Wu, Xl., Sun, Ws., Zhang, Wg. et al. Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure., Chin. J. Integr. Med. 14, 98–102 (2008). https://doi.org/10.1007/s11655-008-0098-0

Xi-li Wu, Wan-sen Sun, Wang-gang Zhang, et al. Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure. [J]. Chinese Journal of Integrative Medicine 14(2):98-102(2008)
Wu, Xl., Sun, Ws., Zhang, Wg. et al. Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure., Chin. J. Integr. Med. 14, 98–102 (2008). https://doi.org/10.1007/s11655-008-0098-0 DOI：

Xi-li Wu, Wan-sen Sun, Wang-gang Zhang, et al. Clinical study of trilogy detoxicating therapy combined with routine Western medicine on patients with chronic renal failure. [J]. Chinese Journal of Integrative Medicine 14(2):98-102(2008) DOI： 10.1007/s11655-008-0098-0.

摘要

To investigate the mechanism of Trilogy Detoxicating Therapy in treating patients with chronic renal failure (CRF). A total of 142 patients were assigned to the Trilogy Detoxicating Therapy group (the treatment group

82 patients) and the Western medicine treatment group (the control group

60 patients). All of the patients were treated with NovoNorm 1 mg and metformin hydrochloride tablets 0.15 g thrice per day for lowering the blood glucose

as well as Perindopril 4 mg twice daily for lowering blood pressure

recombinant human erythropoietin 2 000 U and a hypodermic injection thrice a week for rectifying anemia

30 days as one course of treatment

and all patients were treated for two courses. Patients in the treatment group were treated with the Trilogy Detoxicating Therapy [dispersing the five-zang (脏) organs

expelling toxins through colonic dialysis and skin dialysis fumigation] in addition to the aforementioned drugs. Parameters observed and recorded in the study included renal function [serum creatinine (SCr)

blood urea nitrogen (BUN)]

blood lipids [triglyceride (TG)

total cholesterol (TC)

low-density lipoprotein C (LDL-C)

high-density lipoprotein C (HDL-C)]

plasma total protein (TP)

hemoglobin (Hb)

serum interleukin-6 (IL-6)

and tumor necrosis factor-α (TNF-α) before and after the treatment. After two courses of treatment

the levels of SCr

BUN

LDL-C

serum IL-6 and TNF-α decreased significantly

meanwhile HDL-C increased in the treatment group (P<0.05 or P<0.01). In contrast

no obvious changes of the above mentioned items occurred in the control group. In both groups

the levels of TP and Hb were significantly elevated (P<0.05 or P<0.01)

but the changes were more obvious in the treatment group (P<0.01). Trilogy Detoxicating Therapy played a therapeutic role on patients with CRF possibly through lowering the levels of blood lipids

serum IL-6 and TNF-α.

Abstract

82 patients) and the Western medicine treatment group (the control group

60 patients). All of the patients were treated with NovoNorm 1 mg and metformin hydrochloride tablets 0.15 g thrice per day for lowering the blood glucose

as well as Perindopril 4 mg twice daily for lowering blood pressure

recombinant human erythropoietin 2 000 U and a hypodermic injection thrice a week for rectifying anemia

30 days as one course of treatment

and all patients were treated for two courses. Patients in the treatment group were treated with the Trilogy Detoxicating Therapy [dispersing the five-zang (脏) organs

blood urea nitrogen (BUN)]

blood lipids [triglyceride (TG)

total cholesterol (TC)

low-density lipoprotein C (LDL-C)

high-density lipoprotein C (HDL-C)]

plasma total protein (TP)

hemoglobin (Hb)

serum interleukin-6 (IL-6)

and tumor necrosis factor-α (TNF-α) before and after the treatment. After two courses of treatment

the levels of SCr

BUN

LDL-C

serum IL-6 and TNF-α decreased significantly

meanwhile HDL-C increased in the treatment group (P<0.05 or P<0.01). In contrast

no obvious changes of the above mentioned items occurred in the control group. In both groups

the levels of TP and Hb were significantly elevated (P<0.05 or P<0.01)

but the changes were more obvious in the treatment group (P<0.01). Trilogy Detoxicating Therapy played a therapeutic role on patients with CRF possibly through lowering the levels of blood lipids

serum IL-6 and TNF-α.

关键词

Trilogy Detoxicating Therapychronic renal failureinterleukin-6tumor necrosis factor-α

Keywords

Trilogy Detoxicating Therapychronic renal failureinterleukin-6tumor necrosis factor-α

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Beijing Institute of Traditional Chinese Medicine

Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University

Department of Traditional Chinese Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University

Department of Hepatology, Zhejiang Hospital of Traditional Chinese Medicine

Department Emergency of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

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