Study on syndrome element characteristics and its correlation with coronary angiography in 324 patients with coronary heart disease

Jie Wang; Fu-yong Chu; Jun Li; Kui-wu Yao; Jing-bai Zhong; Ke-hua Zhou; Qing-yong He; Xiao-wei Sun

doi:10.1007/s11655-008-0274-2

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Study on syndrome element characteristics and its correlation with coronary angiography in 324 patients with coronary heart disease

Updated：2021-08-27

- Study on syndrome element characteristics and its correlation with coronary angiography in 324 patients with coronary heart disease
- Chinese Journal of Integrative Medicine Vol. 14, Issue 4, Pages: 274-280(2008)
- Affiliations：
  
  1. Guang ’anmen Hospital, China Academy of Chinese Medical Sciences,Beijing,China
  2. Anzhen Hospital, China Capital University of Medical Science,Beijing,China
  3. Xiyuan Hospital, China Acdemy of Chinese Medical Sciences,Beijing,China
- Author bio：
- Funds：
  
  Supported by Grants from 973 Program of China (No. 2003CB517103)
- DOI：10.1007/s11655-008-0274-2
  CLC：
- Published：2008，
  
  Published Online：12 December 2008，
Scan for full text
Wang, J., Chu, Fy., Li, J. et al. Study on syndrome element characteristics and its correlation with coronary angiography in 324 patients with coronary heart disease., Chin. J. Integr. Med. 14, 274–280 (2008). https://doi.org/10.1007/s11655-008-0274-2

Jie Wang, Fu-yong Chu, Jun Li, et al. Study on syndrome element characteristics and its correlation with coronary angiography in 324 patients with coronary heart disease. [J]. Chinese Journal of Integrative Medicine 14(4):274-280(2008)
Wang, J., Chu, Fy., Li, J. et al. Study on syndrome element characteristics and its correlation with coronary angiography in 324 patients with coronary heart disease., Chin. J. Integr. Med. 14, 274–280 (2008). https://doi.org/10.1007/s11655-008-0274-2 DOI：

Jie Wang, Fu-yong Chu, Jun Li, et al. Study on syndrome element characteristics and its correlation with coronary angiography in 324 patients with coronary heart disease. [J]. Chinese Journal of Integrative Medicine 14(4):274-280(2008) DOI： 10.1007/s11655-008-0274-2.

摘要

Recently

a new traditional Chinese medicine differentiation theory “Syndrome Element (SE)” has been raised. In this study

the main syndrome element types and their correlations with the results of coronary angiography (CAG) in patients with coronary heart disease (CHD) were investigated. Epidemiology cross-sectional study method was employed and 324 patients with CHD were enrolled

and their syndrome element types as well as the CAG results were analyzed. The correlations among syndrome element types

Gensini score

and the number of abnormal branches were also analyzed based on the distribution characteristics of syndrome element and coronary angiography results in the 324 cases. According to their occurrence frequency in 324 CHD patients

the top eight major heart syndrome elements were Xin (心) blood stasis (85.8%)

Xin qi deficiency (79.6%)

Xin heat blockage (41.1%)

Xin phlegm with turbid fluid (38.0%)

Xin qi stagnation (24.7%)

Xin yang deficiency (18.9%)

Xin yin deficiency (17.5%) and Xin cold coagulation (4.4%)

respectively

which suggested that Xin blood stasis and Xin qi deficiency were the two most common syndrome elements. Also

as coronary artery Gensini score increased

the changing trend of the syndrome element was “Xin yang deficiency with blood stasis” to “Xin phlegm obstruction with heat blockage” to “Xin yin deficiency with blood stasis” to “Xin qi deficiency with blood stasis” to “Xin cold coagulation with phlegm and turbid fluid

“Xin cold coagulation with blood stasis” to “Xin deficiency of qi

yin and yang”. As the number of abnormal branches increased

the syndrome element changing trend was “simultaneous occurrence of cold and heat syndrome” to “Xin qi and yang deficiency with blood stasis” to “Xin retention of phlegm with turbid fluid” to “Xin cold coagulation in the heart meridian”

“Xin deficiency of both qi and yin”. The result of this study shows that Xin qi deficiency and Xin blood stasis were the major syndrome elements in patients with CHD. As the severity and extent of coronary artery lesion increased

there were some apparent correlations among syndrome elements

Gensini score and number of abnormal coronary artery branches.

Abstract

Recently

a new traditional Chinese medicine differentiation theory “Syndrome Element (SE)” has been raised. In this study

and their syndrome element types as well as the CAG results were analyzed. The correlations among syndrome element types

Gensini score

the top eight major heart syndrome elements were Xin (心) blood stasis (85.8%)

Xin qi deficiency (79.6%)

Xin heat blockage (41.1%)

Xin phlegm with turbid fluid (38.0%)

Xin qi stagnation (24.7%)

Xin yang deficiency (18.9%)

Xin yin deficiency (17.5%) and Xin cold coagulation (4.4%)

respectively

which suggested that Xin blood stasis and Xin qi deficiency were the two most common syndrome elements. Also

as coronary artery Gensini score increased

“Xin cold coagulation with blood stasis” to “Xin deficiency of qi

yin and yang”. As the number of abnormal branches increased

there were some apparent correlations among syndrome elements

Gensini score and number of abnormal coronary artery branches.

关键词

coronary artery diseasesyndrome elementcoronary angiographyGensini score

Keywords

coronary artery diseasesyndrome elementcoronary angiographyGensini score

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