Supported by the National Natural Science Foundation of China (Nos. 81874380 and 82022075, 81730108 and 81973635), and Zhejiang Province Science and Technology Project of TCM (No. 2021ZQ058),Author Contributions,Yu SX was responsible for writing the manuscript; Liang ZM designed the thesis framework. Yu SX and Liang ZM made equal contributions to this work. Wu QB, Shou L, Huang XX, Zhu QR, Xie H, Mei RY, Zhang RN and Zhai XY collected materials; Xie T and Sui XB guided the manuscript.