Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome

Yu Su-ping; Ye Hui; Ha Nan-lin; Ding Shu-qing; Chen Gao

doi:10.1007/BF02835744

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Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome

OriginalPaper | Updated：2021-08-27

- Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome
- Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome
- 中国结合医学杂志（英文版） 2005年11卷第1期页码：27-30
- Affiliations：
  
  Anorectal Department, Nanjing Municipal TCM Hospital,Nanjing
- Author bio：
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- DOI：10.1007/BF02835744
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- 纸质出版日期：2005，
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Su-ping, Y., Hui, Y., Nan-lin, H. et al. Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome., Chin. J. Integr. Med. 11, 27–30 (2005). https://doi.org/10.1007/BF02835744

Yu Su-ping, Ye Hui, Ha Nan-lin, et al. Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome[J]. Chinese Journal of Integrative Medicine, 2005,11(1):27-30.
Su-ping, Y., Hui, Y., Nan-lin, H. et al. Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome., Chin. J. Integr. Med. 11, 27–30 (2005). https://doi.org/10.1007/BF02835744 DOI：

Yu Su-ping, Ye Hui, Ha Nan-lin, et al. Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome[J]. Chinese Journal of Integrative Medicine, 2005,11(1):27-30. DOI： 10.1007/BF02835744.

摘要

Objective: To explore the mechanism in patients with irritable bowel syndrome (IBS) of the constipation predominant type and observe the therapeutic effects of Sinisan (SNS).Methods: Forty-seven IBS patients with the constipation predominant type were randomly divided into the treated group (n = 24) and the control group (n = 23). Another group of 22 healthy subjects was set up for healthy control. The treated group was treated with modified SNS

and the control group was treated with Cisapride

the therapeutic course for both groups was 8 weeks. The changes of symptom scoring and anorectal manometry (the anorectal resting pressure

anal tract systolic pressure

anal tract diastolic pressure

rectal threshold feeling

maximal tolerance volume of rectum

and rectum compliance) of these two groups were recorded respectively and compared with each other.Results: Compared with the healthy control group

the rectal threshold feeling

maximal tolerance volume of rectum and rectal compliance of the treated groups got reduced significantly before treatment (P<0.05). After treatment

the symptom scoring

rectal threshold feeling and maximal tolerance volume of rectum were improved in both groups (P<0.05)

and the improvement of the treated group was more significant than that of the control group(P<0. 01). The total effective rate and recurrence rate of the treated group were superior to those of the control group significantly (P<0.05

P<0.01).Conclusion: SNS has good effect on IBS of the constipation predominant type.

Abstract

and the control group was treated with Cisapride

the therapeutic course for both groups was 8 weeks. The changes of symptom scoring and anorectal manometry (the anorectal resting pressure

anal tract systolic pressure

anal tract diastolic pressure

rectal threshold feeling

maximal tolerance volume of rectum

and rectum compliance) of these two groups were recorded respectively and compared with each other.Results: Compared with the healthy control group

the rectal threshold feeling

maximal tolerance volume of rectum and rectal compliance of the treated groups got reduced significantly before treatment (P<0.05). After treatment

the symptom scoring

rectal threshold feeling and maximal tolerance volume of rectum were improved in both groups (P<0.05)

P<0.01).Conclusion: SNS has good effect on IBS of the constipation predominant type.

关键词

Irritable Bowel Syndromeconstipation-predominant typeAnorectal ManometrySinisan

Keywords

Irritable Bowel Syndromeconstipation-predominant typeAnorectal ManometrySinisan

references

Thompson WG. The Road to Rome. Gut 1999; 45 (Supl II): II 80.

Wei BH. TCM syndrome differentiation and treatment of GI motility disturbances disorder. Chin J CWM Diges 2003;11(5): 259.

Camilleri M, Prsather CM. The irritable bowel syndrome: mechanisms and a practical approach to management. Ann Intern Med 1992;116(12): 1001.

Shen YJ. Chinese drugs pharmacology. Beijing: People’s Medical Publishing House, 2000: 547,632,1072.

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