Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment

Wei Ling; Tan Jie

doi:10.1007/BF02835745

Your Location：

Home >

Browse articles >

Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment

OriginalPaper | Updated：2021-08-27

- Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment
- Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment
- 中国结合医学杂志（英文版） 2005年11卷第1期页码：31-33
- Affiliations：
  
  Department of Gerontology, The Fifth Hospital Affiliated to Sun Yat-sen University,Guangdong Province
- Author bio：
- Funds：
- DOI：10.1007/BF02835745
  中图分类号：
- 纸质出版日期：2005，
Scan for full text
Ling, W., Jie, T. Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment., Chin. J. Integr. Med. 11, 31–33 (2005). https://doi.org/10.1007/BF02835745

Wei Ling, Tan Jie. Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment[J]. Chinese Journal of Integrative Medicine, 2005,11(1):31-33.
Ling, W., Jie, T. Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment., Chin. J. Integr. Med. 11, 31–33 (2005). https://doi.org/10.1007/BF02835745 DOI：

Wei Ling, Tan Jie. Clinical observation on Breviscapine in treating hypertension patients complicated with micro-albuminuria of renal impairment[J]. Chinese Journal of Integrative Medicine, 2005,11(1):31-33. DOI： 10.1007/BF02835745.

摘要

Objective: To evaluate the efficacy of Breviscapine on essential hypertension (EH) patients complicated with micro-albuminuria of renal impairment.Methods: Seventy-six EH patients were randomly assigned to the control group and the treated group

the former was given amlodipine

captopril/uropidil and the latter was given in addition Breviscapine intravenously dripped for 2 treatment courses. The indexes of serum creatinine (Cr)

blood urea nitrogen (BUN)

blood and urinary β2-microglobulin (β2-MG)

and quantitative determination of 24 hrs urinary protein were evaluated before and after treatment.Results: In the control group

compared with before treatment

the quantitative determination of 24 hrs urinary protein got reduced significantly (P<0.05)

while in the treated group

both urinary β2-MG and quantitative determination of 24 hrs urinary protein got lowered significantly (P<0.05 andP<0.01). But after treatment

compared with the control group

urinary β2-MG and quantitative determination of 24 hrs urinary protein in the treated group were obviously reduced (P<0.05).Conclusion: Besides lowering blood pressure effectively

Breviscapine could improve the renal function significantly and reduce the urinary micro-albuminuria

hence showing promising effect on renal protection.

Abstract

the former was given amlodipine

captopril/uropidil and the latter was given in addition Breviscapine intravenously dripped for 2 treatment courses. The indexes of serum creatinine (Cr)

blood urea nitrogen (BUN)

blood and urinary β2-microglobulin (β2-MG)

and quantitative determination of 24 hrs urinary protein were evaluated before and after treatment.Results: In the control group

compared with before treatment

the quantitative determination of 24 hrs urinary protein got reduced significantly (P<0.05)

while in the treated group

both urinary β2-MG and quantitative determination of 24 hrs urinary protein got lowered significantly (P<0.05 andP<0.01). But after treatment

compared with the control group

urinary β2-MG and quantitative determination of 24 hrs urinary protein in the treated group were obviously reduced (P<0.05).Conclusion: Besides lowering blood pressure effectively

Breviscapine could improve the renal function significantly and reduce the urinary micro-albuminuria

hence showing promising effect on renal protection.

关键词

BreviscapineEssential Hypertensionmicro-albuminuriarenal impairment

Keywords

BreviscapineEssential Hypertensionmicro-albuminuriarenal impairment

references

Xu DL, Ren H. Diagnosis, prevention and treatment of essential hypertension renal impairment. Chin J Cardiovasc 2004;32(2): 190–191.

Tang Z, Ji DX, Li LS. Effect of anti-hypertension treatment on rats’ chronic renal failure. J Nephr Dialys Kid Transpl 1995;8(4): 324.

Jiang XF, Qi XQ, Sun XH, et al. Clinical study on hypertension patients with early renal tubule impairment. Prac Med J 1999;15(10): 775–776.

Jia Q. The renal protective effect of angiotensin invertase inhibitor and angiotensin II receptor antagonist combined application. Chin Compreh Clin 2004;19(8): 677–678.

He MC. Clinical efficacy observation of Yunnan Breviscapine injection. Chin J Hemorheol 1999;9(3): 191–192.

FULL TEXT LINK

More>

浏览量

420

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Effect of chinese herbal medicine for calming Gan (肝) and suppressing hyperactive yang on arterial elasticity function and circadian rhythm of blood pressure in patients with essential hypertension

Effects of Xuezhikang (血脂康) and pravastatin on circulating endothelial progenitor cells in patients with essential hypertension

Study on insulin resistance and genetic polymorphisms in essential hypertension patients of two different kinds of TCM constitution

Clinical study on zhenjian granule in improving essential hypertension and insulin resistance

Effect of theo-polyphenols on oxygen free radicals and hemorheology in patients with essential hypertension