Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction

Kang Yi; Lin Xiu-zhen

doi:10.1007/BF02836359

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Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction

OriginalPaper | Updated：2021-08-27

- Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction
- Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction
- 中国结合医学杂志（英文版） 2003年9卷第1期页码：57-59
- Affiliations：
  
  Department of Pharmacology, Tianjin Medical University,Tianjin
- Author bio：
- Funds：
  
  This project was supported by the State’s Key Projects of the Tenth Five-year Plan (No. 969030105)
- DOI：10.1007/BF02836359
  中图分类号：
- 纸质出版日期：2003，
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Yi, K., Xiu-zhen, L. Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction., Chin. J. Integr. Med. 9, 57–59 (2003). https://doi.org/10.1007/BF02836359

Kang Yi, Lin Xiu-zhen. Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction[J]. Chinese Journal of Integrative Medicine, 2003,9(1):57-59.
Yi, K., Xiu-zhen, L. Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction., Chin. J. Integr. Med. 9, 57–59 (2003). https://doi.org/10.1007/BF02836359 DOI：

Kang Yi, Lin Xiu-zhen. Effect of Dachengqi Tang granule on proliferation of intestinal epithelial cells in rats with experimental intestinal obstruction[J]. Chinese Journal of Integrative Medicine, 2003,9(1):57-59. DOI： 10.1007/BF02836359.

摘要

Objective: To study the effects of Dachengqi Tang (DCQT) granule on the proliferation of the intestinal epithelial cells in rats with experimental intestinal obstruction.Methods: Experimental intestinal obstruction models were established in rats and autoradiography with3 H-TdR was used to determine3H-TdR labeling counts of intestinal epithelial cells in rats.Results: DCQT granule had no effects on3H-TdR labeling counts of intestinal epithelial cells in normal rats. DCQT granule obviously increases the rate of renovation in intestinal epithelial cells of the intestinal obstruction rats.Conclusion: DCQT granule could reinforce the intestinal mucosa’s defensive function by means of increasing the proliferation of intestinal epithelial cells.

Abstract

关键词

Dachengqi Tang granuleIntestinal Epithelial CellDefensive Functionproliferation

Keywords

Dachengqi Tang granuleIntestinal Epithelial CellDefensive Functionproliferation

references

ZHOU JH, WANG JH. The protective effects of Dachengqi decoction with effect of removing stasis by purgation on intestinal barrier function. Advances of pharmacological and clinical study of TCM. Beijing: Military Medical Publishing House, 1995: 254–261.

GUO SD, KANG Y, WU XZ. Effects of each single ingredient of Dachengqi decoction on45 Ca influx of isolated colon smooth muscles from the experimental colon obstruction in rats. Chin J Integr Tradi West Med (Chin) 1991;11(supl): 277–279.

KANG Y, GUO SD, WU XZ. Effects of Dachengqi decoction on lipidperoxidation. Chin J Integr Tradi West Med (Chin) 1991;11(supl): 371–372.

KANG Y, GUO SD, LIN XZ. Study of Dachengqi decoction on45 Ca content of the isolated colon smooth muscle from experimental colon obstruction rats. Chin J Integr Tradi West Med (Chin) 1991;11(supl): 107–109.

GAO FM and JIANG HY. Studies on kinetics of the intestinal epithelium in mice by autoradiography. Acta Zoologica Sinica 1982;28(1): 1–7.

ZHOU JH. Prospect on integrated traditional Chinese and western medicine and pharmacology in the 21st century. CMJ 1999;112(4): 242–246.

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