Relationship of adrenocortical function and TCM Syndrome typing in elderly patients with severe sepsis

Wu Hai-yun; Wei Cheng-yun; Zhu Guang-qing; Xu Qiang; Zhang Jian; Wang Shi-wen

doi:10.1007/BF02836374

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Relationship of adrenocortical function and TCM Syndrome typing in elderly patients with severe sepsis

OriginalPaper | Updated：2021-08-27

- Relationship of adrenocortical function and TCM Syndrome typing in elderly patients with severe sepsis
- Relationship of adrenocortical function and TCM Syndrome typing in elderly patients with severe sepsis
- 中国结合医学杂志（英文版） 2004年10卷第2期页码：91-95
- Affiliations：
  
  1. Institute of Geriatric Cardiology, General Hospital of PLA,Beijing
  2. Beijing Municipal Hospital of Integrated Traditional and Western Medicine attached to Beijing University of TCM,China
  3. General Hospital of the Air Force,PLA,China
- Author bio：
- Funds：
  
  This study was supported by the National “973” Project of China (No. G2000057004)
- DOI：10.1007/BF02836374
  中图分类号：
- 纸质出版日期：2004，
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Hai-yun, W., Cheng-yun, W., Guang-qing, Z. et al. Relationship of adrenocortical function and TCM Syndrome typing in elderly patients with severe sepsis., Chin. J. Integr. Med. 10, 91–95 (2004). https://doi.org/10.1007/BF02836374

Wu Hai-yun, Wei Cheng-yun, Zhu Guang-qing, et al. Relationship of adrenocortical function and TCM Syndrome typing in elderly patients with severe sepsis[J]. Chinese Journal of Integrative Medicine, 2004,10(2):91-95.
Hai-yun, W., Cheng-yun, W., Guang-qing, Z. et al. Relationship of adrenocortical function and TCM Syndrome typing in elderly patients with severe sepsis., Chin. J. Integr. Med. 10, 91–95 (2004). https://doi.org/10.1007/BF02836374 DOI：

Wu Hai-yun, Wei Cheng-yun, Zhu Guang-qing, et al. Relationship of adrenocortical function and TCM Syndrome typing in elderly patients with severe sepsis[J]. Chinese Journal of Integrative Medicine, 2004,10(2):91-95. DOI： 10.1007/BF02836374.

摘要

Objective: To explore the relationship between TCM Syndrome typing and adrenocortical function in elderly patients with severe sepsis

and to see whether TCM Syndrome Differentiation can provide clinical clues in identifying relative adrenal insufficiency (RAI) in patients with severe sepsis.Methods: Sixty-one old patients with severe sepsis were classified into four types according to TCM Syndrome Differentiation: The severe invasion of toxic-heat type (Type SITH

n = 21); the Qi stagnation and blood stasis type (Type QSBS

n = 11); the sudden depletion of Yang-Qi type (Type SDYQ

n = 16); and the exhaustion of Qi-Yin type (Type EOQY

n = 13). The base-line level of plasma cortisol in patients of different types and their response to corticotropin stimulation were compared

which were also compared with those of 12 healthy elderly persons synchronously.Results: The base-line level of plasma cortisol was not significantly different between patients of different Syndrome types (P>0.05)

but they were all sgnificantly higher than that in the healthy persons (P<0.05). Compared with Type QSBS and Type EOQY

Type SITH and Type SDYQ showed less cortisol concentration increment after corticotropin stimulation (P<0.05). RAI was more prevalent in patients of Type SITH and Type SDYQ than in patients of Type QSBS and Type EOQY (57% vs 25%

P<0.01).Conclusion: In old patients with severe sepsis

different TCM Syndrome types are associated with different adrenocortical function status. TCM Syndrome differentiation can provide clinical clues in identifying old patients with severe sepsis who have also RAI.

Abstract

Objective: To explore the relationship between TCM Syndrome typing and adrenocortical function in elderly patients with severe sepsis

n = 21); the Qi stagnation and blood stasis type (Type QSBS

n = 11); the sudden depletion of Yang-Qi type (Type SDYQ

n = 16); and the exhaustion of Qi-Yin type (Type EOQY

n = 13). The base-line level of plasma cortisol in patients of different types and their response to corticotropin stimulation were compared

but they were all sgnificantly higher than that in the healthy persons (P<0.05). Compared with Type QSBS and Type EOQY

P<0.01).Conclusion: In old patients with severe sepsis

关键词

adrenal functioncortisolsepsisTraditional Chinese MedicineSyndrome Type

Keywords

adrenal functioncortisolsepsisTraditional Chinese MedicineSyndrome Type

references

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Cooper MS, Stewart PM. Corticosteroid insufficiency in acutely ill patients. N Engl J Med 2003; 348: 727–734.

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Cronin L, Cook DJ, Carlet J, et al. Corticosteroid treatment for sepsis: A critical appraisal and meta-analysis of the literature. Crit Care Med 1995; 23: 1430–1439.

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